Zobrazeno 1 - 10
of 23
pro vyhledávání: '"T E Carew"'
Publikováno v:
Journal of Lipid Research, Vol 18, Iss 4, Pp 451-458 (1977)
Binding of 125I-low density lipoprotein (LDL) and 125I-high density lipoprotein (HDL) was determined in cultured human fibroblasts from a normal subject and two subjects with homozygous familial hypercholesterolemia (HFH). Binding was assayed at 0 °
Externí odkaz:
https://doaj.org/article/1bc0588ae2974eaa9cb6c3dd750d324d
Publikováno v:
Journal of Lipid Research, Vol 17, Iss 5, Pp 441-450 (1976)
Turnover of 125I-low density lipoprotein (LDL) and of 131I-high density lipoprotein (HDL) was determined before and after end-to-side portacaval shunt in eight swine. LDL (d 1.019–1.063) and HDL (d.1.09–1.21) were isolated by ultracentrifugation
Externí odkaz:
https://doaj.org/article/4d8b61b86da44bd29c4c2a22e68e9543
Publikováno v:
Journal of Lipid Research, Vol 26, Iss 1, Pp 92-103 (1985)
In previous animal studies, bile acid sequestrant resins have been shown to increase the fractional catabolic rate (FCR) of a low density lipoprotein (LDL) tracer isolated from a normal donor animal and to increase hepatic LDL-receptor activity. In a
Externí odkaz:
https://doaj.org/article/ed2087f9c2d64143b18abe28576cd777
Publikováno v:
Journal of Lipid Research, Vol 30, Iss 2, Pp 225-238 (1989)
We investigated the effect of the bile acid sequestrant, colestipol hydrochloride, on the composition and metabolism of human low density lipoprotein (LDL). Colestipol treatment produced a disproportionate decrease in LDL cholesterol compared to LDL
Externí odkaz:
https://doaj.org/article/45480750e8a6475ebadb358d6d47a1f0
Publikováno v:
Journal of Lipid Research, Vol 28, Iss 9, Pp 1098-1109 (1987)
Immunological mechanisms have been implicated in the atherogenic process since immunoglobulins are frequently found in the atherosclerotic aorta. We have previously shown that modifications of homologous low density lipoproteins (LDL) make it immunog
Externí odkaz:
https://doaj.org/article/ea8f865b75344e14951cb4a960449b91
Autor:
H A, Lehr, A M, Olofsson, T E, Carew, P, Vajkoczy, U H, von Andrian, C, Hübner, M C, Berndt, D, Steinberg, K, Messmer, K E, Arfors
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 71(3)
Oxidized low density lipoprotein (oxLDL) has been demonstrated to stimulate leukocyte/endothelium interaction, an early feature of atherogenesis. Using the skinfold chamber model for intravital microscopy in hamsters and mice, we have shown that oxLD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55b47f8ed11c232a5294504acae7d0d9
https://pubmed.ncbi.nlm.nih.gov/7523762
https://pubmed.ncbi.nlm.nih.gov/7523762
Publikováno v:
Biochemical Journal. 212:791-800
We recently developed a general method for determining tissue sites of degradation of plasma proteins in vivo that made use of covalently attached radioactive sucrose. On degradation of the protein, the sucrose remained trapped in the cells as a cumu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a5d50741a6f4cddeda32fb019dbabe
https://doi.org/10.1042/bj2120791
https://doi.org/10.1042/bj2120791
Publikováno v:
Journal of Biological Chemistry. 257:7994-8000
Low density lipoprotein (LDL) catabolism was studied using WHHL rabbits, an inbred strain deficient in LDL receptor activity and, thus, an animal model for homozygous familial hypercholesterolemia. WHHL and normal rabbits were injected with [14C]sucr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec5720bdd349867e7c77a6efb43a7dee
https://doi.org/10.1016/s0021-9258(18)34287-x
https://doi.org/10.1016/s0021-9258(18)34287-x
Publikováno v:
Journal of Biological Chemistry. 257:8001-8008
Low density lipoprotein (LDL) is catabolized by both receptor-dependent and receptor-independent pathways; methylated LDL (MeLDL) is catabolized only by receptor-independent mechanisms. Rats were injected with either LDL or MeLDL labeled with [14C]su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6783ec28c76c35fbef65fedfdf815b3e
https://doi.org/10.1016/s0021-9258(18)34288-1
https://doi.org/10.1016/s0021-9258(18)34288-1
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 244:E101-E107
The sites of albumin catabolism were determined in rabbits using [14C]sucrose-labeled rabbit albumin. The [14C]sucrose moiety is not degradable and accumulates in tissues degrading the protein. Albumin was labeled with [14C]sucrose, and the monomeric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a4e7e5f8b26e85e7dfbdce90c26d8b
https://doi.org/10.1152/ajpendo.1983.244.1.e101
https://doi.org/10.1152/ajpendo.1983.244.1.e101