Zobrazeno 1 - 10
of 34
pro vyhledávání: '"T E, Morgan"'
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract Microglia affect Alzheimer’s disease (AD) pathogenesis in opposing manners, by protecting against amyloid accumulation in early phases of the disease and promoting neuropathology in advanced stages. Recent research has identified specific
Externí odkaz:
https://doaj.org/article/ddeb950f09e042628e7f1608bd921f0a
Autor:
Caleb E Finch, T E Morgan
Publikováno v:
Frontiers in Aging Neuroscience, Vol 7 (2015)
In a perimenopausal model of middle aged rats, the astrocyte estrogen receptor-alpha (ERa): ER-beta (ERb) ratio increased with the onset of acyclicity (constant estrus, CE) in association with impaired neurotrophic responses to estradiol (E2). We rep
Externí odkaz:
https://doaj.org/article/e88b275a726144e5bf16693b59b7de1f
Publikováno v:
Experimental Mechanics. 58:125-135
Traumatic brain injury (TBI) is a form of acquired brain trauma in which sudden external mechanical insults damage brain structures and cells. With a wide range of severities, TBI induces inflammatory responses with neurodegeneration and dysfunction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d80ac87046c3eff7035fb7267bc1c4f
https://doi.org/10.1007/s11340-017-0338-3
https://doi.org/10.1007/s11340-017-0338-3
Publikováno v:
Journal of Endocrinology. 149:19-27
Transforming growth factor β1 (TGFβ1) has recently been shown to be produced in the prolactin (PRL)-secreting lactotropes of the pituitary gland. TGFβ1 inhibits lactotropic secretion and proliferation, and the production of TGFβ1 in lactotropes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de24916fe28fb4518fbf76805c2d8a16
https://doi.org/10.1677/joe.0.1490019
https://doi.org/10.1677/joe.0.1490019
Publikováno v:
The Journal of Cell Biology
Actin depolymerizing factor (ADF) is an 18.5-kD protein with pH-dependent reciprocal F-actin binding and severing/depolymerizing activities. We previously showed developing muscle down-regulates ADF (J. R. Bamburg and D. Bray. 1987. J. Cell Biol. 105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ffcdd9a09159f5fc402d7e806ef9b26
http://europepmc.org/articles/PMC2119666
http://europepmc.org/articles/PMC2119666
Publikováno v:
Interdisciplinary topics in gerontology. 35
Dietary restriction (DR) remains the most powerful and general environmental manipulation of aging processes in laboratory animals with strong beneficial effects on most age-related degenerative changes throughout the body. Underlying the beneficial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e76257e3021ed6838c9513ab9bc8053e
https://pubmed.ncbi.nlm.nih.gov/17063034
https://pubmed.ncbi.nlm.nih.gov/17063034
Autor:
M P, Lambert, K L, Viola, B A, Chromy, L, Chang, T E, Morgan, J, Yu, D L, Venton, G A, Krafft, C E, Finch, W L, Klein
Publikováno v:
Journal of neurochemistry. 79(3)
In recent studies of transgenic models of Alzheimer's disease (AD), it has been reported that antibodies to aged beta amyloid peptide 1-42 (Abeta(1-42)) solutions (mixtures of Abeta monomers, oligomers and amyloid fibrils) cause conspicuous reduction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9880cc20830fbfed15fb58f92f4f15c3
https://pubmed.ncbi.nlm.nih.gov/11701763
https://pubmed.ncbi.nlm.nih.gov/11701763
Publikováno v:
Neuroscience letters. 215(2)
During aging, rodent and human brains show progressive increases in the levels of glial fibrillary acidic protein (GFAP) mRNA and protein. The role of transcription was investigated by in situ hybridization, using an intron-containing cRNA probe as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5da590de538da6a59c723b6cb092b210
https://pubmed.ncbi.nlm.nih.gov/8888007
https://pubmed.ncbi.nlm.nih.gov/8888007