Zobrazeno 1 - 10
of 16
pro vyhledávání: '"T E, Kwasigroch"'
Publikováno v:
Progress in clinical and biological research.
Autor:
T. E. Kwasigroch, D. M. Kochhar
Publikováno v:
Anatomy and Embryology. 161:105-113
Maternal administration of a single dose of retinoic acid (vitamin A acid, 100 mg/kg) on either the 11 th, 11 1/2, 12th, 12 1/2, 13th or 13 1/2 day of gestation produced phocomelia or partial phocomelia in ICR/DUB fetuses. The results depended upon t
Autor:
T. E. KWASIGROCH, R. G. SKALKO
Publikováno v:
Toxicological Sciences. 5:1161-1173
Autor:
Richard G. Skalko, T. E. Kwasigroch
Publikováno v:
Toxicology Letters. 21:339-347
Caffeine and retinoic acid were examined for effects upon limb morphogenesis and upon creatine kinase (CK) as a measure of limb myogenesis. Caffeine at 200 mg/kg, i.p., on E11 produced a low level of forelimb (1.2%) and hindlimb (2.0%) defects. Retin
Autor:
T. E. Kwasigroch, D. M. Kochhar
Publikováno v:
Development. 59:325-339
Two techniques were used to examine the effect of vitamin A compounds (vitamin A acid = retinoic acid and vitamin A acetate) upon the relative strengths of adhesion among mouse limb-bud mesenchymal cells. Treatment with retinoic acid in vivo and with
Publikováno v:
The Anatomical Record. 206:341-344
Forty cross sections of a male cadaver were prepared for a Continuing Medical Education Seminar and have been used in teaching programs for the past 3 years. The sections are easy and inexpensive to construct and can be maintained with a minimal amou
Autor:
R G, Skalko, T E, Kwasigroch
Publikováno v:
Progress in clinical and biological research.
Publikováno v:
Teratogenesis, carcinogenesis, and mutagenesis. 4(3)
Retinoic acid, suspended in cottonseed oil, was administered via gavage to pregnant mice (ICR strain) on day 11 (E 11) of gestation at doses of either 20, 40, or 80 mg/kg. Fetuses were examined for external malformations on day 17 (E 17). Retinoic ac
Autor:
R G, Skalko, T E, Kwasigroch
Publikováno v:
Biological research in pregnancy and perinatology. 4(1)
The role of chemical interactions in the genesis of induced embryotoxicity in humans and in experimental animals is a point of current concern and interest. This review summarizes the current knowledge in this field and demonstrates that, under appro
Autor:
Diether Neubert, T. E. Kwasigroch
Publikováno v:
Teratogenesis, carcinogenesis, and mutagenesis. 1(2)
Forelimbs of mouse fetuses were examined for tissue-specific, drug-induced alterations in their biochemical composition. The activity of the enzyme creatine phospholinase (CPK; to estimate myogenesis) and the content of hydroxyproline (HP; to estimat