Výsledky vyhledávání - "T D Kierstead"

Adding an Rb-binding site to an N-terminally truncated simian virus 40 T antigen restores growth to high cell density, and the T common region in trans provides anchorage-independent growth and rapid growth in low serum concentrations

Autor: Mary J. Tevethia, Holly A. Lacko, D L Thompson, T D Kierstead

Publikováno v: Journal of Virology. 71:1888-1896

The simian virus 40 large T antigen is sufficient to confer on cells multiple transformed cell growth characteristics, including growth to a high cell density, rapid growth in medium containing low serum concentrations, and anchorage-independent grow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a3e1774cb2727b71b235aa643871b9
https://doi.org/10.1128/jvi.71.3.1888-1896.1997

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Association of p53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 T-antigen mutants bearing internal overlapping deletion mutations

Autor: Mary J. Tevethia, T D Kierstead

To more precisely map the immortalization and p53 binding domains of T antigen, a large series of overlapping deletion mutations were created between codons 251 to 651 by utilizing a combination of Bal 31 deletion and oligonucleotide-directed mutagen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5f3f87f87cc237815485f473cf7143
https://europepmc.org/articles/PMC240236/

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