Výsledky vyhledávání - "T D Kierstead"

Adding an Rb-binding site to an N-terminally truncated simian virus 40 T antigen restores growth to high cell density, and the T common region in trans provides anchorage-independent growth and rapid growth in low serum concentrations

Autor: Mary J. Tevethia, Holly A. Lacko, D L Thompson, T D Kierstead

Publikováno v: Journal of Virology. 71:1888-1896

The simian virus 40 large T antigen is sufficient to confer on cells multiple transformed cell growth characteristics, including growth to a high cell density, rapid growth in medium containing low serum concentrations, and anchorage-independent grow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a3e1774cb2727b71b235aa643871b9
https://doi.org/10.1128/jvi.71.3.1888-1896.1997

Zobrazit plný text záznamu

Association of p53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 T-antigen mutants bearing internal overlapping deletion mutations

Autor: Mary J. Tevethia, T D Kierstead

To more precisely map the immortalization and p53 binding domains of T antigen, a large series of overlapping deletion mutations were created between codons 251 to 651 by utilizing a combination of Bal 31 deletion and oligonucleotide-directed mutagen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5f3f87f87cc237815485f473cf7143
https://europepmc.org/articles/PMC240236/

Zobrazit plný text záznamu

Akademický článek

Optogenetically engineered Septin-7 enhances immune cell infiltration of tumor spheroids.

Autor: Jiaxing Chen, Hnath, Brianna, Sha, Congzhou M., Beidler, Lynne, Schell, Todd D., Dokholyan, Nikolay V.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; 10/29/2024, Vol. 121 Issue 44, p1-12, 31p

Zobrazit plný text záznamu

Periodical

Simian virus 40 large T antigen contains two independent activities that cooperate with a ras oncogene to transform rat embryo fibroblasts

Autor: Cavender, J F, Conn, A, Epler, M, Lacko, H, Tevethia, M J

Publikováno v: The Journal of Virology; February 1995, Vol. 69 Issue: 2 p923-934, 12p

Zobrazit plný text záznamu

Simian virus 40 large T antigen contains two independent activities that cooperate with a ras oncogene to transform rat embryo fibroblasts

Autor: Mary J. Tevethia, Melanie Epler, Holly A. Lacko, Ardell Conn, J F Cavender

Publikováno v: Journal of virology. 69(2)

The simian virus 40 large T antigen immortalizes growing primary cells in culture. In addition, this viral oncoprotein cooperates with an activated ras protein to produce dense foci on monolayers of rat embryo fibroblasts (REF). The relationship betw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4979ef5286c6a832f882f12b29fc9dab
https://pubmed.ncbi.nlm.nih.gov/7815561

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání