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LIM domain-containing protein trip6 can act as a coactivator for the v-Rel transcription factor

Autor: M K, Zhao, Y, Wang, K, Murphy, J, Yi, M C, Beckerle, T D, Gilmore

Publikováno v: Gene expression. 8(4)

The retroviral oncoprotein v-Rel is a transcriptional activator in the Rel/NF-kappaB family of eukaryotic transcription factors. v-Rel malignantly transforms a variety of cell types in vitro and in vivo, and its transforming activity is dependent on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b58fd67c8286e15f1ba599896f817280
https://pubmed.ncbi.nlm.nih.gov/10794523

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Rel/NF-kappaB/IkappaB proteins and cancer

Autor: T D, Gilmore, M, Koedood, K A, Piffat, D W, White

Publikováno v: Oncogene. 13(7)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c907d325016b43b22b2782b78dbda7d0
https://pubmed.ncbi.nlm.nih.gov/8875974

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Bcl-2 and CrmA have different effects on transformation, apoptosis and the stability of I kappa B-alpha in chicken spleen cells transformed by temperature-sensitive v-Rel oncoproteins

Autor: D W, White, T D, Gilmore

Publikováno v: Oncogene. 13(5)

The retroviral oncoprotein v-Rel is a member of the Rel/ NF-kappa B family of transcription factors. We have previously characterized two v-Rel mutants (v-G37E and v-R273H) that are temperature-sensitive (ts) for transformation and immortalization of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d271b497e22e779cd53063b41b5bf9e5
https://pubmed.ncbi.nlm.nih.gov/8806678

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Interaction of the v-Rel oncoprotein with NF-kappaB and IkappaB proteins: heterodimers of a transformation-defective v-Rel mutant and NF-2 are functional in vitro and in vivo

Autor: D W, White, G A, Pitoc, T D, Gilmore

Publikováno v: Molecular and cellular biology. 16(3)

The v-Rel oncoprotein of the avian Rev-T retrovirus is a member of the Rel/NF-kappa B family of transcription factors. The mechanism by which v-Rel malignantly transforms chicken spleen cells is not precisely known. To gain a better understanding of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::77ded37d7b1a5ace73b756200744a4f9
https://pubmed.ncbi.nlm.nih.gov/8622661

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Genetic analysis of growth inhibition by GAL4-L kappa B-alpha in Saccharomyces cerevisiae

Autor: P J, Morin, J A, Downs, A M, Snodgrass, T D, Gilmore

Publikováno v: Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 6(7)

I kappa B proteins bind to and regulate Rel/NF- kappa B transcription factors. We showed previously that a fusion protein (GAL4-p40) containing the DNA-binding domain of GAL4 and sequences of chicken l kappa B-alpha (p40) inhibits growth in the yeast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ef6a33ada9e4b025cf77514a70f6a6a
https://pubmed.ncbi.nlm.nih.gov/7547500

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The v-Rel oncoprotein blocks apoptosis and proteolysis of I kappa B-alpha in transformed chicken spleen cells

Autor: D W, White, A, Roy, T D, Gilmore

Publikováno v: Oncogene. 10(5)

The v-Rel oncoprotein of the avian Rev-T retrovirus malignantly transforms chicken spleen cells in vivo and in vitro. We previously described two temperature-sensitive (ts) mutants of v-Rel (v-G37E and v-R273H) that show a ts ability to transform chi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::82aeb5b0711b7c905dc3b44c67cb447a
https://pubmed.ncbi.nlm.nih.gov/7898928

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The I kappa B proteins: members of a multifunctional family

Autor: T D, Gilmore, P J, Morin

Publikováno v: Trends in genetics : TIG. 9(12)

The I kappa B proteins bind to Rel/NF-kappa B transcription factors and modulate their activities. Although originally described only as cytoplasmic inhibitors of Rel/NF-kappa B transcription complexes, it is now clear that I kappa B proteins also ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c4bdb0d7101e084c87703f40399e1916
https://pubmed.ncbi.nlm.nih.gov/8122310

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The v-Rel oncoprotein increases expression from Sp1 site-containing promoters in chicken embryo fibroblasts

Autor: S, Sif, A J, Capobianco, T D, Gilmore

Publikováno v: Oncogene. 8(9)

The v-Rel oncoprotein of the avian Rev-T retrovirus is a member of a family of related transcription factors, which also includes the subunits of NF-kappa B and several other interacting cellular proteins. We show here that v-Rel specifically increas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c9f9c07f1f8a4fed3c4d1fa76fff5efd
https://pubmed.ncbi.nlm.nih.gov/8361761

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Transformation by the vRel oncoprotein requires sequences carboxy-terminal to the Rel homology domain

Autor: S, Sarkar, T D, Gilmore

Publikováno v: Oncogene. 8(8)

The vRel oncoprotein of the avian Rev-T retrovirus is a member of the Rel/NF-kappa B family of transcription factors. The highly conserved amino-terminal Rel Homology (RH) domain in these proteins is required for DNA binding, protein-protein interact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6447f1a3104e0fc73deef88e58907e03
https://pubmed.ncbi.nlm.nih.gov/8336947

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