Zobrazeno 1 - 10
of 80
pro vyhledávání: '"T Cuperus"'
Autor:
Sayeh Gorjifard, Tobias Jores, Jackson Tonnies, Nicholas A. Mueth, Kerry Bubb, Travis Wrightsman, Edward S. Buckler, Stanley Fields, Josh T. Cuperus, Christine Queitsch
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The 3’ end of a gene, often called a terminator, modulates mRNA stability, localization, translation, and polyadenylation. Here, we adapted Plant STARR-seq, a massively parallel reporter assay, to measure the activity of over 50,000 termin
Externí odkaz:
https://doaj.org/article/908d5cba8923462d9ec5479ec926226a
Autor:
Elizabeth X. Kwan, Gina M. Alvino, Kelsey L. Lynch, Paula F. Levan, Haley M. Amemiya, Xiaobin S. Wang, Sarah A. Johnson, Joseph C. Sanchez, Madison A. Miller, Mackenzie Croy, Seung-been Lee, Maria Naushab, Antonio Bedalov, Josh T. Cuperus, Bonita J. Brewer, Christine Queitsch, M.K. Raghuraman
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112161- (2023)
Summary: Timely completion of genome replication is a prerequisite for mitosis, genome integrity, and cell survival. A challenge to this timely completion comes from the need to replicate the hundreds of untranscribed copies of rDNA that organisms ma
Externí odkaz:
https://doaj.org/article/52aee668d64145149ab27041aab50554
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-27 (2021)
Abstract Background The 3′ untranslated region (UTR) plays critical roles in determining the level of gene expression through effects on activities such as mRNA stability and translation. Functional elements within this region have largely been ide
Externí odkaz:
https://doaj.org/article/a05db5009b264eb8844a0af1068e245a
Autor:
Michael W. Dorrity, Cristina M. Alexandre, Morgan O. Hamm, Anna-Lena Vigil, Stanley Fields, Christine Queitsch, Josh T. Cuperus
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Existing studies of the chromatin accessibility, the primary mark of regulatory DNA, in Arabidopsis are based mainly on bulk samples. Here, the authors report the regulatory landscape of Arabidopsis thaliana roots at single-cell resolution.
Externí odkaz:
https://doaj.org/article/e6ea871c17df432cb5dc0bf940a6480c
Autor:
Cristina M Alexandre, Kerry L Bubb, Karla M Schultz, Janne Lempe, Josh T Cuperus, Christine Queitsch
Isogenic individuals can display seemingly stochastic phenotypic differences, limiting the accuracy of genotype-to-phenotype predictions. The extent of this phenotypic variation depends in part on genetic background, raising questions about the genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b635129a5940e0cbd3bb8ae5cf3da0ef
https://doi.org/10.1101/2023.05.11.540469
https://doi.org/10.1101/2023.05.11.540469
Publikováno v:
GENETICS. 224
The genes that encode ribosomal RNAs are present in several hundred copies in most eukaryotes. These vast arrays of repetitive ribosomal DNA (rDNA) have been implicated not just in ribosome biogenesis, but also aging, cancer, genome stability, and gl
Autor:
Josh T. Cuperus
Publikováno v:
Plant Physiology. 188:749-755
Single-cell genomics has the potential to revolutionize the study of plant development and tissue-specific responses to environmental stimuli by revealing heretofore unknown players and gene regulatory processes. Here, I focus on the current state of
Autor:
Travis Wrightsman, Stanley Fields, Tobias Jores, Josh T. Cuperus, Edward S. Buckler, Jackson Tonnies, Christine Queitsch
Publikováno v:
Nat Plants
Targeted engineering of plant gene expression holds great promise for ensuring food security and for producing biopharmaceuticals in plants. However, this engineering requires thorough knowledge of cis-regulatory elements to precisely control either
Autor:
Stanley Fields, Anna-Lena Vigil, Michael W. Dorrity, Cristina M. Alexandre, Josh T. Cuperus, Christine Queitsch, Morgan O. Hamm
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
The scarcity of accessible sites that are dynamic or cell type-specific in plants may be due in part to tissue heterogeneity in bulk studies. To assess the effects of tissue heterogeneity, we apply single-cell ATAC-seq to Arabidopsis thaliana roots a
Autor:
Tzitziki Lemus, Grace Alex Mason, Kerry L Bubb, Cristina M Alexandre, Christine Queitsch, Josh T Cuperus
Publikováno v:
Genetics.
Argonaute 1 (AGO1), the principal protein component of microRNA-mediated regulation, plays a key role in plant growth and development. AGO1 physically interacts with the chaperone HSP90, which buffers cryptic genetic variation in plants and animals.