Zobrazeno 1 - 10
of 27
pro vyhledávání: '"T Chandramohan, Reddy"'
Autor:
Chandrani Achari, T. Chandramohan Reddy, V. Lakshmipathi, Gorla V. Reddy, A. Subramanyam, A. Aparna, D. Bharat Reddy, Geetika Gupta, Pallu Reddanna, Kalle M. Arunasree
Publikováno v:
Toxicology in Vitro. 26:396-405
Gallic acid (GA) induces apoptosis in various cancer cell lines. In this study, we investigated the apoptotic activity induced by GA on chronic myeloid leukemia (CML) cell line-K562 and the underlying mechanism. GA reduced the viability of K562 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8f95942739c34fa9791581a00b8f10
https://doi.org/10.1016/j.tiv.2011.12.018
https://doi.org/10.1016/j.tiv.2011.12.018
Autor:
P. Ramu Sridhar, Pallu Reddanna, Polamarasetty Aparoy, Chandrani Achari, Nimmanapalli P. Reddy, T. Chandramohan Reddy
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:5807-5815
Ten novel mono- and di-O-prenylated chalcone derivatives were designed on the basis of a homology derived molecular model of 5-lipoxygenase (5-LOX). The compounds were docked into 5-LOX active site and the binding characteristics were quantified usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d9f6fdf1874ea4a62d399233e0fcf3
https://doi.org/10.1016/j.bmc.2010.06.107
https://doi.org/10.1016/j.bmc.2010.06.107
Autor:
Pallu Reddanna, M.K. Arunasree, Karnati R. Roy, Devalraju Sreekanth, Gorla V. Reddy, T. Chandramohan Reddy
Publikováno v:
Phytomedicine. 14:739-746
Betalains are water-soluble nitrogenous vacuolar pigments present in flowers and fruits of many caryophyllales with potent antioxidant properties. In the present study the antiproliferative effects of betanin, a principle betacyanin pigment, isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b661cab3def042aa46899b87e1e77ba6
https://doi.org/10.1016/j.phymed.2007.03.017
https://doi.org/10.1016/j.phymed.2007.03.017
Publikováno v:
Journal of Social Sciences. 5:193-199
On widowhood an individual’s living arrangement gains significance as it provides an opportunity for support and has an edge in specific areas of support due to close physical proximity. In Indian ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b25b1a6bb6b463d1a8b999a5a5616a5f
https://doi.org/10.1080/09718923.2001.11892305
https://doi.org/10.1080/09718923.2001.11892305
Publikováno v:
The Anthropologist. 2:153-159
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0127e729c09cdd68fe727e7b173fd79a
https://doi.org/10.1080/09720073.2000.11890649
https://doi.org/10.1080/09720073.2000.11890649
Autor:
K Anil, Kumar, T Chandramohan, Reddy, Gorla V, Reddy, D Bharat Kumar, Reddy, S V K, Mahipal, Sudhir, Sinha, Anil N, Gaikwad, P, Reddanna
Publikováno v:
Indian journal of biochemistrybiophysics. 48(4)
High-throughput screening (HTS) involves testing of compound libraries against validated drug targets using quantitative bioassays to identify 'hit' molecules that modulate the activity of target, which forms the starting point of a drug discovery ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8d509739c79d4017df441e1046073b3
https://pubmed.ncbi.nlm.nih.gov/22053694
https://pubmed.ncbi.nlm.nih.gov/22053694
Autor:
Chandrani Achari, Polamarasetty Aparoy, T. Chandramohan Reddy, Pallu Reddanna, P. Ramu Sridhar, Nimmanapalli P. Reddy
Publikováno v:
European journal of medicinal chemistry. 47(1)
A group of 4-(benzyloxy)-1-phenylbut-2-yn-1-ol derivatives were designed using Site point connection method, synthesized and evaluated for their 5-Lipoxygenase (5-LOX) inhibitory activity. Hydrophobic site points in 5-LOX were considered for the stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be85d47437ecd6a46de02f658064e761
https://pubmed.ncbi.nlm.nih.gov/22118829
https://pubmed.ncbi.nlm.nih.gov/22118829
Autor:
Suresh K. Kalangi, Pallu Reddanna, Kakularam Kumar Reddy, T. Chandramohan Reddy, Polamarasetty Aparoy
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(3)
Inhibitors of the 5-Lipoxygenase (5-LOX) pathway have a therapeutic potential in a variety of inflammatory disorders such as asthma. In this study, chemical feature based pharmacophore models of inhibitors of 5-LOX have been developed with the aid of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450e3bb08e1c4d3dbbd24636d3e17d90
https://pubmed.ncbi.nlm.nih.gov/20045317
https://pubmed.ncbi.nlm.nih.gov/20045317
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