Zobrazeno 1 - 10
of 370 715
pro vyhledávání: '"T Cell Receptor"'
T cell receptor signaling must operate reliably under tight time constraints. While assuming quite different mechanisms, two prominent models of T cell receptor activation, kinetic segregation and kinetic proofreading, both introduce a distinct time
Externí odkaz:
http://arxiv.org/abs/2412.06773
Autor:
Pyo, Andrew G. T., Nagano, Yuta, Milighetti, Martina, Henderson, James, Callan Jr., Curtis G., Chain, Benny, Wingreen, Ned S., Tiffeau-Mayer, Andreas
The biophysical interactions between the T cell receptor (TCR) and its ligands determine the specificity of the cellular immune response. However, the immense diversity of receptors and ligands has made it challenging to discover generalizable rules
Externí odkaz:
http://arxiv.org/abs/2412.13722
Identifying T-cell receptors (TCRs) that interact with antigenic peptides provides the technical basis for developing vaccines and immunotherapies. The emergent deep learning methods excel at learning antigen binding patterns from known TCRs but stru
Externí odkaz:
http://arxiv.org/abs/2411.17798
Autor:
Cieslak, Cassandra1 (AUTHOR), Hain, Carsten2 (AUTHOR), Rückert-Reed, Christian2 (AUTHOR), Busche, Tobias2 (AUTHOR), Klages, Levin Joe2 (AUTHOR), Schaper-Gerhardt, Katrin1 (AUTHOR), Gutzmer, Ralf1 (AUTHOR), Kalinowski, Jörn2 (AUTHOR) joern@cebitec.uni-bielefeld.de, Stadler, Rudolf1 (AUTHOR) joern@cebitec.uni-bielefeld.de
Publikováno v:
Cancers. Nov2024, Vol. 16 Issue 21, p3700. 12p.
Autor:
Linhu Hui1, Fengli Wu1, Yuanyuan Xu1, Guangjun Yang2, Qiaorong Luo3, Yangyang Li1, Long Ma1, Xinsheng Yao1, Jun Li1 huosu2014@163.com
Publikováno v:
Animal Bioscience. Dec2024, Vol. 37 Issue 12, p2178-2188. 11p.
Autor:
Yang, Meng1 (AUTHOR), He, Dan1 (AUTHOR), Sun, Yu2 (AUTHOR), Guo, Yunquan1 (AUTHOR), Ma, Yu3 (AUTHOR), Feng, Lin2 (AUTHOR), Liu, Meng1 (AUTHOR) liuxiaomeng198154@163.com
Publikováno v:
Journal of Translational Medicine. 11/27/2024, Vol. 22 Issue 1, p1-13. 13p.
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a malignant neoplasm with detrimental implications for human health. The landscape of ESCC therapy has been revolutionized by the introduction of immunotherapy, specifically involving i
Externí odkaz:
https://doaj.org/article/cbff68607cde4c7eb4022dd69fc6cb51
T-cell receptors (TCRs) play a crucial role in the immune system by recognizing and binding to specific antigens presented by infected or cancerous cells. Understanding the sequence patterns of TCRs is essential for developing targeted immune therapi
Externí odkaz:
http://arxiv.org/abs/2408.01156
Autor:
Boone E; Department of Laboratory Medicine, Laboratory for Molecular Diagnostics, AZ Delta Hospital, Roeselare, Belgium., Groenen PJTA; Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands., Langerak AW; Department of Immunology, Laboratory Medical Immunology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands. a.langerak@erasmusmc.nl.
Publikováno v:
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2025; Vol. 2865, pp. 77-102.