Zobrazeno 1 - 10
of 20
pro vyhledávání: '"T C T M van der Pouw Kraan"'
Autor:
Gerd Bouma, Lisa C. Laan, Elsenoor J. Klaver, Richard D. Cummings, I. van Die, T C T M van der Pouw Kraan, Helene Kringel, Georg Kraal
Publikováno v:
Genes and Immunity, 16(6), 378-387
Klaver, E J, van der Pouw-Kraan, T C T M, Laan, L C, Kringel, H, Cummings, R D, Bouma, G, Kraal, G & van Die, I 2015, ' Trichuris suis soluble products induce Rab7b expression and limit TLR4 responses in human dendritic cells ', Genes and Immunity, vol. 16, no. 6, pp. 378-387 . https://doi.org/10.1038/gene.2015.18
Klaver, E J, van der Pouw-Kraan, T C T M, Laan, L C, Kringel, H, Cummings, R D, Bouma, G, Kraal, G & van Die, I 2015, ' Trichuris suis soluble products induce Rab7b expression and limit TLR4 responses in human dendritic cells ', Genes and Immunity, vol. 16, no. 6, pp. 378-387 . https://doi.org/10.1038/gene.2015.18
Inflammatory immune disorders such as inflammatory bowel disease and multiple sclerosis are major health problems. Currently, the intestinal whipworm Trichuris suis is being explored in clinical trials to reduce inflammation in these diseases; howeve
Autor:
Cornelis L. Verweij, T C T M van der Pouw Kraan, Paul P. Tak, Alexandre E. Voskuyl, Ben A. C. Dijkmans, L G M van Baarsen, François Rustenburg, J.M. Baggen, Carla A. Wijbrandts
Publikováno v:
Genes and Immunology, 9(1), 16-22
van der Pouw Kraan, C T M, van Baarsen, L G, Wijbrandts, C A, Voskuyl, A E, Rustenburg, F, Baggen, J M, Dijkmans, B A C, Tak, P P & Verweij, C L 2008, ' Expression of a pathogen-response program in peripheral blood cells defines a subgroup of rheumatoid arthritis patients ', Genes and Immunology, vol. 9, no. 1, pp. 16-22 .
Genes and immunity, 9(1), 16-22. Nature Publishing Group
van der Pouw Kraan, C T M, van Baarsen, L G, Wijbrandts, C A, Voskuyl, A E, Rustenburg, F, Baggen, J M, Dijkmans, B A C, Tak, P P & Verweij, C L 2008, ' Expression of a pathogen-response program in peripheral blood cells defines a subgroup of rheumatoid arthritis patients ', Genes and Immunology, vol. 9, no. 1, pp. 16-22 .
Genes and immunity, 9(1), 16-22. Nature Publishing Group
Rheumatoid arthritis (RA) is a heterogeneous disease with unknown etiology. Here we aimed to distinguish RA subtypes based on peripheral blood (PB) gene expression profiles in comparison with a pathogen-response transcriptional program. PB was obtain
Autor:
J.J. Kragt, T Hooper, J F Meilof, Chris H. Polman, T C T M van der Pouw Kraan, L G M van Baarsen, François Rustenburg, Cornelis L. Verweij, Christine D. Dijkstra, J.M. Baggen, Mike Fero
Publikováno v:
Genes and immunity, 7(6), 522-531. Nature Publishing Group
Given the heterogeneous nature of multiple sclerosis (MS), we applied DNA microarray technology to determine whether variability is reflected in peripheral blood (PB) cells. In this study, we studied whole-blood gene expression profiles of 29 patient
Autor:
Twj Huizinga, F. A. van Gaalen, F. C. Breedveld, T C T M van der Pouw Kraan, Elsbet J. Pieterman, Cornelis L. Verweij
Publikováno v:
van der Pouw Kraan, TC, van Gaalen, FA, Huizinga, T W, Pieterman, E, Breedveld, F C & Verweij, C L 2003, ' Discovery of distinctive gene expression profiles in rheumatoid synovium using cDNA microarray technology: evidence for the existence of multiple pathways of tissue destruction and repair. ', Genes and Immunity, vol. 4, no. 3, pp. 187-96 . https://doi.org/10.1038/sj.gene.6363975
Genes and Immunity, 4(3), 187-96
Genes and Immunity, 4(3), 187-96
Rheumatoid arthritis (RA) is a heterogeneous disease. We used cDNA microarray technology to subclassify RA patients and disclose disease pathways in rheumatoid synovium. Hierarchical clustering of gene expression data identified two main groups of ti
Autor:
Gijs Kooij, Elsenoor J. Klaver, M K Ottow, Helene Kringel, Daphne Y.S. Vogel, T C T M van der Pouw Kraan, Lisa C. Laan, Christine D. Dijkstra, Priscilla D. A. M. Heijnen, I. van Die
Publikováno v:
Ottow, M K, Klaver, E J, van der Pouw Kraan, C T M, Heijnen, P D, Laan, L C, Kringel, H, Vogel, D Y S, Dijkstra, C D, Kooij, G & van Die, I 2014, ' The helminth Trichuris suis suppresses TLR4-induced inflammatory responses in human macrophages ', Genes and Immunity, vol. 15, no. 7, pp. 477-486 . https://doi.org/10.1038/gene.2014.38
Genes and Immunity, 15(7), 477-486
Genes and Immunity, 15(7), 477-486
Recent clinical trials in patients with inflammatory diseases like multiple sclerosis (MS) or inflammatory bowel disease (IBD) have shown the beneficial effects of probiotic helminth administration, although the underlying mechanism of action remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e884f8a68c9b625555b01604dba8ed6
https://research.vumc.nl/en/publications/ac62dea1-e50e-4b02-9205-e5f7c2612548
https://research.vumc.nl/en/publications/ac62dea1-e50e-4b02-9205-e5f7c2612548
Autor:
A. Snijders, T C T M van der Pouw Kraan, I M Zonneveld, Martien L. Kapsenberg, Jan Wormmeester, P. Widjaja, Jan D. Bos, M. Engel
Publikováno v:
Clinical and experimental immunology, 111(3), 472-476. Wiley-Blackwell
SUMMARYAD is associated with a bias of the T helper cells to show increased IL-4 and reduced interferon-gamma (IFN-γ) production. The production of IFN-γ and IL-4 and the development of Th cells into either high IFN-γ or high IL-4 producers is str
Autor:
L. A. Aarden, A. E. Alewijnse, L. C. M. Boeije, E. de Groot, A. Snijders, T C T M van der Pouw Kraan, R. (Rob) Leurs
Publikováno v:
Journal of Clinical Investigation, 102(10), 1866-1873. The American Society for Clinical Investigation
Journal of clinical investigation, 102(10), 1866-1873. The American Society for Clinical Investigation
van der Pouw Kraan, C T M, Snijders, A, Boeije, L C M, Groot, E R, Alewijnse, A E, Leurs, R & Aarden, L A 1998, ' Histamine inhibits the production of interleukin-12 through interaction with H2 receptors. ', Journal of Clinical Investigation, vol. 102, no. 10, pp. 1866-1873 . https://doi.org/10.1172/JCI3692
Journal of clinical investigation, 102(10), 1866-1873. The American Society for Clinical Investigation
van der Pouw Kraan, C T M, Snijders, A, Boeije, L C M, Groot, E R, Alewijnse, A E, Leurs, R & Aarden, L A 1998, ' Histamine inhibits the production of interleukin-12 through interaction with H2 receptors. ', Journal of Clinical Investigation, vol. 102, no. 10, pp. 1866-1873 . https://doi.org/10.1172/JCI3692
IL-12 is essential for T helper 1 (Th1) development and inhibits the induction of Th2 responses. Atopic diseases, which are characterized by Th2 responses, are associated with the overproduction of histamine. Here we present evidence that histamine,
Autor:
C. E. Hack, G. Van Mierlo, W C J Hop, R. de Groot, René F. Kornelisse, Herman J. Neijens, M. H. Suur, Huub F. J. Savelkoul, T. C. T. M. Van Der Pouw Kraan
Publikováno v:
Infection & Immunity, 65(3), 877-881. American Society for Microbiology
Infection and Immunity, 65, 877-881. American Society for Microbiology
Infection and Immunity, 65, 877-881. American Society for Microbiology
To assess the role of interleukin-12 (IL-12) and gamma interferon (IFN-gamma) in children with bacterial meningitis, bioactive IL-12 (p70) and the inactive subunit p40 and IFN-gamma were measured in serum and cerebrospinal fluid (CSF) from 35 childre
Publikováno v:
The Journal of Experimental Medicine
During human immunodeficiency virus infection and allergic diseases, characterized by a dominant T helper (Th) 2 response, overproduction of prostaglandin E2 (PGE2) is observed. In this paper we studied the effect of PGE2 on interleukin (IL)-12 synth
Autor:
Cornelis L. Verweij, D.M. Pegtel, C. J. van der Laken, Ingrid E. Lundberg, S de Ridder, Michael T. Nurmohamed, T C T M van der Pouw Kraan, John G. Wesseling, Jiri Vencovsky, Joep Killestein, Elise Mantel, Florian Deisenhammer, T. D. de Jong, D. van Schaardenburg, A E Voskuyl, Saskia Vosslamber, Harald Hegen, Irene E. M. Bultink, Cyra E. Leurs, J. W. J. Bijlsma
Publikováno v:
Annals of the Rheumatic Diseases. 75:A52.1-A52
Background and objectives Upregulation of type I IFN response genes is described for several autoimmune diseases, including systemic lupus erythematosus (SLE), multiple sclerosis (MS), myositis (IIM) and rheumatoid arthritis (RA). While IFNα contrib