Zobrazeno 1 - 10 of 72 pro vyhledávání: '"T C Spelsberg"'
1
Relationship between DNA Ploidy and Functional Estrogen Receptors in Operable Prostate Cancer
Autor: T C Spelsberg, Terry M. Therneau, George M. Farrow, Michael M. Lieber, Ofer Nativ, D S Colvard, T Umehara
Publikováno v: European Urology. 32:96-99
Objective: To evalute the relationship between the nuclear DNA content and the tissue estrogen receptor (ER) level in patients with operable adenocarcinoma of the prostate. Method: Surgical specimens taken from 73 patients with clinically localized p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6dbd8b4f55efee8cb64ebdac115bd02f
https://doi.org/10.1159/000480888
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2
Scanning multiple samples simultaneously in tube-based microCT systems
Autor: T. C. Spelsberg, Stuart R. Stock, Nalini M. Rajamannan, Yan Chen, Mahesh Polavarapu, S. Malayannan, Rehan Riaz, Erin L. Hsu, Ming Zhang, Wellington K. Hsu
Publikováno v: Developments in X-Ray Tomography VII.
The world-wide explosion of commercial microComputed Tomography (microCT) system emplacement has led to dayin, day-out access to laboratory scanners. Most biologically-oriented microCT facilities must characterize large numbers of samples rapidly at
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::380be577596b998c52f4d40731b138a6
https://doi.org/10.1117/12.860691
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4
Tissue-specific expression of bone proteins in femora of growing rats
Autor: S. N. Kapelner, Russell T. Turner, T. C. Spelsberg
Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 263:E724-E729
Total cellular RNA was extracted from bone cells of three different femoral compartments of 2-mo-old rats. The intact femora were first incubated with collagenase to obtain periosteal cells. The bisected periosteum-free diaphyses and metaphyses were
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4d29826a2958c6e1be6e240b7c2b51
https://doi.org/10.1152/ajpendo.1992.263.4.e724
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6
The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated
Autor: F, Gori, L C, Hofbauer, C R, Dunstan, T C, Spelsberg, S, Khosla, B L, Riggs
Publikováno v: Endocrinology. 141(12)
The one or more molecular mechanisms that determine the obligatory sequence of resorption followed by formation during bone remodeling is unclear. RANK ligand (RANK-L) is an essential requirement for osteoclastogenesis, and its activity is neutralize
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eb509200157ebe72ca8943a27d10370c
https://pubmed.ncbi.nlm.nih.gov/11108292
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7
Bisphosphonates directly regulate cell proliferation, differentiation, and gene expression in human osteoblasts
Autor: G G, Reinholz, B, Getz, L, Pederson, E S, Sanders, M, Subramaniam, J N, Ingle, T C, Spelsberg
Publikováno v: Cancer research. 60(21)
Bisphosphonates are widely used clinically to treat bone diseases in which bone resorption is in excess. However, the mechanism of bisphosphonate action on bone is not fully understood. Studies of direct action of bisphosphonates on bone have been li
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::039bd783e2515dd3c0032fe8f4408182
https://pubmed.ncbi.nlm.nih.gov/11085520
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8
Cytokine-specific induction of the TGF-beta inducible early gene (TIEG): regulation by specific members of the TGF-beta family
Autor: T E, Hefferan, M, Subramaniam, S, Khosla, B L, Riggs, T C, Spelsberg
Publikováno v: Journal of cellular biochemistry. 78(3)
Select members of the TGF-beta family of cytokines play key regulatory roles in skeletal development, structure, and turnover. This laboratory has previously reported that TGF-beta treatment of immortalized normal human fetal osteoblast (hFOB) cells
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::006a92ae70cc716b4ee6df074e0ce354
https://pubmed.ncbi.nlm.nih.gov/10861837
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9
Molecular and cellular mechanisms of estrogen action on the skeleton
Autor: D J, Rickard, M, Subramaniam, T C, Spelsberg
Publikováno v: Journal of cellular biochemistry.
The many recent and exciting advances that have taken place in the field of estrogen action on the skeleton are the subjects of this review. Leading these new developments is the discovery of alternative estrogen receptors that exhibit differential m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::926453ffaffd6673bc5c2f0518cde1ac
https://pubmed.ncbi.nlm.nih.gov/10629111
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10
Identification of breast cancer cell line-derived paracrine factors that stimulate osteoclast activity
Autor: L, Pederson, B, Winding, N T, Foged, T C, Spelsberg, M J, Oursler
Publikováno v: Cancer research. 59(22)
Metastatic breast cancer causes destruction of significant amounts of bone, and, although bone is the most likely site of breast cancer metastasis, little is understood about interactions between tumor cells and bone-resorbing osteoclasts. We have in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::49e497e257395750395c7671296f6319
https://pubmed.ncbi.nlm.nih.gov/10582709
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