Zobrazeno 1 - 10
of 30
pro vyhledávání: '"T C Meeker"'
Publikováno v:
Molecular and Cellular Biology. 11:4846-4853
The t(11;14)(q13;q32) translocation has been associated with human B-lymphocytic malignancy. Several examples of this translocation have been cloned, documenting that this abnormality joins the immunoglobulin heavy-chain gene to the bcl-1 locus on ch
Publikováno v:
Blood. 78:493-498
Centrocytic lymphoma is a B-cell non-Hodgkin's lymphoma (NHL) composed of lymphocytes resembling cleaved follicular center cells (centrocytes). Previous studies have suggested an association between t(11;14) chromosomal translocations and bcl-1 rearr
Publikováno v:
Molecular and Cellular Biology. 10:1680-1688
The expression of the Pim-1 proto-oncogene was studied by using the K562, Daudi, and Jurkat cell lines. In K562, Pim-1 mRNA levels were more than 20-fold higher than in Daudi and 50-fold higher than in Jurkat. Nuclear run-on assay data correlated dir
Publikováno v:
Cancer gene therapy. 3(4)
In this work we have explored the use of adenoviral vectors for the purging of cancer cells from hematopoietic stem cell (HSC) autografts. We showed that a recombinant adenovirus expressing the herpes simplex-1 thymidine kinase gene (AD-tk) plus ganc
Autor:
L D, Kaplan, B, Shiramizu, B, Herndier, J, Hahn, T C, Meeker, V, Ng, P A, Volberding, M S, McGrath
Publikováno v:
Blood. 85(7)
The relationship between clinical and molecular characteristics of 45 treated individuals with histologically-documented human immunodeficiency virus (HIV)-associated B-cell non-Hodgkin's lymphoma was examined to determine whether differences in mole
Publikováno v:
Leukemia. 7(9)
Chromosome 11q13 translocation breakpoints have been found dispersed over more than 100 kb of genomic DNA in centrocytic lymphoma and lymphocytic lymphoma of intermediate differentiation (mantle cell lymphoma). Approximately one-half of these translo
Autor:
C W, Richard, M, Boehnke, D J, Berg, J H, Lichy, T C, Meeker, E, Hauser, R M, Myers, D R, Cox
Publikováno v:
American journal of human genetics. 52(5)
We describe a high-resolution radiation hybrid (RH) map of the distal short arm of human chromosome 11 containing the Beckwith-Wiedemann gene and the associated embryonal tumor disease loci. Thirteen human 11p15 genes and 17 new anonymous probes were
Autor:
J B, Faust, T C, Meeker
Publikováno v:
Cancer research. 52(9)
The bcl-1 gene maps to chromosome 11q13 and has recently been shown to be a member of the cyclin gene family. Amplification of the chromosome region containing bcl-1 occurs frequently in breast cancer, squamous cell cancer, and other tumor types. We
Autor:
T C, Meeker, B, Shiramizu, L, Kaplan, B, Herndier, H, Sanchez, J C, Grimaldi, J, Baumgartner, J, Rachlin, E, Feigal, M, Rosenblum
Publikováno v:
AIDS (London, England). 5(6)
The pathogenesis of the HIV-associated lymphomas is not well understood. In order to begin characterizing this class of lymphoma, we initiated a molecular genetic study of DNA extracted from 31 diagnostic biopsy specimens from patients diagnosed with
Publikováno v:
Journal of acquired immune deficiency syndromes. 4(4)
High-grade non-Hodgkins B-cell lymphoma is one of the principle malignancies that occurs in individuals infected with the human immunodeficiency virus (HIV-1). Immunoblastic lymphomas that arise in immunosuppressed transplant patients have been descr