Zobrazeno 1 - 8
of 8
pro vyhledávání: '"T C J M Arentsen-Peters"'
Autor:
Tamara C. A. I. Verbeek, Kirsten S. Vrenken, Susan T. C. J. M. Arentsen-Peters, Patricia Garrido Castro, Marieke van de Ven, Olaf van Tellingen, Rob Pieters, Ronald W. Stam
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract KMT2A-rearranged acute lymphoblastic leukemia (ALL) is characterized by deregulation of the epigenome and shows susceptibility towards histone deacetylase (HDAC) inhibition. Most broad-spectrum HDAC inhibitors simultaneously target multiple
Externí odkaz:
https://doaj.org/article/e000296a1f8e439791267dfa6e9c542d
Autor:
Priscilla Wander, Susan T. C. J. M. Arentsen-Peters, Kirsten S. Vrenken, Sandra Mimoso Pinhanҫos, Bianca Koopmans, M. Emmy M. Dolman, Luke Jones, Patricia Garrido Castro, Pauline Schneider, Mark Kerstjens, Jan J. Molenaar, Rob Pieters, Christian Michel Zwaan, Ronald W. Stam
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 638 (2022)
KMT2A-rearranged acute lymphoblastic leukemia (ALL) in infants (KMT2A-rearranged infant ALL patient samples (n = 2). The most effective drugs were then tested on non-leukemic whole bone marrow samples (n = 2) to select drugs with a favorable therapeu
Externí odkaz:
https://doaj.org/article/7815cb20aae54d3d99175e3e8348e9d7
Autor:
Priscilla, Wander, Laurence C, Cheung, Sandra S, Pinhanҫos, Luke, Jones, Mark, Kerstjens, Susan T C J M, Arentsen-Peters, Sajla, Singh, Grace-Alyssa, Chua, Patricia Garrido, Castro, Pauline, Schneider, M Emmy M, Dolman, Bianca, Koopmans, Jan J, Molenaar, Rob, Pieters, C Michel, Zwaan, Rishi S, Kotecha, Ronald W, Stam
Publikováno v:
Leukemia. 34(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::730ec35526f19fe94883f8b15fa9c872
https://pubmed.ncbi.nlm.nih.gov/32488115
https://pubmed.ncbi.nlm.nih.gov/32488115
Autor:
Askar Obulkasim, Jan Trka, Martin Zimmermann, D Valerio, E Sonneveld, A A Danen-van Oorschot, N S D Larmonie, Dirk Reinhardt, V de Haas, Maarten Fornerod, M.M. van den Heuvel-Eibrink, Christian M. Zwaan, Rob Pieters, André Baruchel, T C J M Arentsen-Peters
Publikováno v:
Oncogene, 37(1), 107-115. Nature Publishing Group
In acute myeloid leukemia (AML), specific genomic aberrations induce aberrant methylation, thus directly influencing the transcriptional programing of leukemic cells. Therefore, therapies targeting epigenetic processes are advocated as a promising th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a4edd5b1907cc441ffca539653018c
https://doi.org/10.1038/onc.2017.293
https://doi.org/10.1038/onc.2017.293
Acute myeloid leukaemia in a case with Tatton-Brown-Rahman syndrome: the peculiarDNMT3AR882 mutation
Autor:
C. Michel Zwaan, Ans M.W. van den Ouweland, H. Berna Beverloo, Susan T C J M Arentsen-Peters, Iris H.I.M. Hollink, Anja Wagner
Publikováno v:
Journal of Medical Genetics, 54(12), 805-808. BMJ Publishing Group
Background Recently a novel syndromic form of overgrowth with intellectual disability and distinct facial features was identified caused by constitutional mutations in the epigenetic regulator DNA-methyltransferase 3A ( DNMT3A ), referred to as Tatto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba9723613fa69e462c048bf14ad3346
https://doi.org/10.1136/jmedgenet-2017-104574
https://doi.org/10.1136/jmedgenet-2017-104574
Autor:
B.A. van der Reijden, Joost H.A. Martens, Nilofar Sharifi, Hendrik G. Stunnenberg, Eva M. Janssen-Megens, Joop H. Jansen, Christian M. Zwaan, Saskia M. Bergevoet, Bowon Kim, Mathijs A. Sanders, J Knijnenburg, Anna E. Marneth, Peter J. M. Valk, Maarten Fornerod, A. S. Al Hinai, T C J M Arentsen-Peters, Torsten Haferlach, Jorren Kuster, E C G Stoetman, Marie-Laure Yaspo, Niccolò Tesi, M M van den Heuvel-Eibrink, Koen H.M. Prange
Publikováno v:
Leukemia : the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K.
Leukemia, 32(3), 828-836. Nature Publishing Group
Leukemia, 32, pp. 828-836
Leukemia, 32, 828-836. Macmillan Publishers Limited, part of Springer Nature.
Leukemia, 32(3), 828-836
Leukemia, 32(3), 828-836. Nature Publishing Group
Leukemia, 32, pp. 828-836
Leukemia, 32, 828-836. Macmillan Publishers Limited, part of Springer Nature.
Leukemia, 32(3), 828-836
Overexpression of the BRE (brain and reproductive organ-expressed) gene defines a distinct pediatric and adult acute myeloid leukemia (AML) subgroup. Here we identify a promoter enriched for active chromatin marks in BRE intron 4 causing strong biall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0991d6d688f32e57394edc14b63b95c
https://doi.org/10.1038/leu.2017.280
https://doi.org/10.1038/leu.2017.280
Autor:
Iris H I M, Hollink, Ans M W, van den Ouweland, H Berna, Beverloo, Susan T C J M, Arentsen-Peters, C Michel, Zwaan, Anja, Wagner
Publikováno v:
Journal of medical genetics. 54(12)
Recently a novel syndromic form of overgrowth with intellectual disability and distinct facial features was identified caused by constitutional mutations in the epigenetic regulator DNA-methyltransferase 3A (Here we present the first case of TBRS who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f876a6c2c05884e09c6aa81150f2817a
https://pubmed.ncbi.nlm.nih.gov/28432085
https://pubmed.ncbi.nlm.nih.gov/28432085
Autor:
Ursula Creutzig, S S N de Graaf, Jacqueline Cloos, Christian Thiede, Gertjan J.L. Kaspers, Dirk Reinhardt, Iris H.I.M. Hollink, Rob Pieters, Martin Zimmermann, T C J M Arentsen-Peters, Christian M. Zwaan, M M van den Heuvel-Eibrink, Jochen Harbott
Publikováno v:
Leukemia, 23, 2, pp. 262-70
Hollink, I H I M, Zwaan, C M, Zimmermann, M, Arentsen-Peters, S T C J M, Pieters, R, Cloos, J, Kaspers, G J L, de Graaf, S, Harbott, J, Creutzig, U, Reinhardt, D, van den Heuvel-Eibrink, M & Thiede, C 2009, ' Favorable prognostic impact of NPM1 gene mutations in childhood acute myeloid leukemia, with emphasis on cytogenetically normal AML ', Leukemia, vol. 23, no. 2, pp. 262-270 . https://doi.org/10.1038/leu.2008.313
Leukemia, 23(2), 262-270. Nature Publishing Group
Leukemia, 23, 262-270. Nature Publishing Group
Leukemia, 23, 262-70
Hollink, I H I M, Zwaan, C M, Zimmermann, M, Arentsen-Peters, S T C J M, Pieters, R, Cloos, J, Kaspers, G J L, de Graaf, S, Harbott, J, Creutzig, U, Reinhardt, D, van den Heuvel-Eibrink, M & Thiede, C 2009, ' Favorable prognostic impact of NPM1 gene mutations in childhood acute myeloid leukemia, with emphasis on cytogenetically normal AML ', Leukemia, vol. 23, no. 2, pp. 262-270 . https://doi.org/10.1038/leu.2008.313
Leukemia, 23(2), 262-270. Nature Publishing Group
Leukemia, 23, 262-270. Nature Publishing Group
Leukemia, 23, 262-70
Item does not contain fulltext Nucleophosmin (NPM1) mutations occur frequently in adult cytogenetically normal acute myeloid leukemia (CN-AML) and confer favorable outcome. We investigated the frequency and prognostic significance of NPM1 mutations i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7461df0946a5455365c79889cd53ad2
https://doi.org/10.1038/leu.2008.313
https://doi.org/10.1038/leu.2008.313