Zobrazeno 1 - 10
of 201
pro vyhledávání: '"T C, Wun"'
Autor:
T C Wun, K K Kretzmer, Peter G. Tipping, Jonathan Erlich, Stephen R. Holdsworth, J. Apostolopoulos
Publikováno v:
Journal of Clinical Investigation. 98:325-335
Tissue factor pathway inhibitor (TFPI) was demonstrated in the kidneys of normal rabbits and in a crescentic model of glomerulonephritis (GN), where fibrin is a key mediator of injury. In normal kidneys, TFPI was expressed in glomeruli, in intrarenal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84f51dbe78add8ba69181c5637cf048
https://doi.org/10.1172/jci118796
https://doi.org/10.1172/jci118796
Autor:
K C, Day, L C, Hoffman, M O, Palmier, K K, Kretzmer, M D, Huang, E Y, Pyla, E, Spokas, G J, Broze, T G, Warren, T C, Wun
Publikováno v:
Blood. 76:1538-1545
Lipoprotein-associated coagulation inhibitor produces feed-back inhibition of tissue factor (tissue thromboplastin)-induced coagulation in the presence of factor Xa Recombinant lipoprotein-associated coagulation inhibitor (rLACI) was tested for its a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10315df4f2f3d6da6ec7f861261d8708
https://doi.org/10.1182/blood.v76.8.1538.bloodjournal7681538
https://doi.org/10.1182/blood.v76.8.1538.bloodjournal7681538
Publikováno v:
Europe PubMed Central
Urokinase-type plasminogen activator (uPA) binds to a specific receptor on various cell types, the bound molecule retaining its enzymatic activity against plasminogen. We have now investigated whether receptor-bound uPA also retains the ability to re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de31a0def691720b49ebbdbdcf640832
https://doi.org/10.1016/s0021-9258(19)38757-5
https://doi.org/10.1016/s0021-9258(19)38757-5
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Thrombosis and haemostasis. 80(3)
An important regulator of the initiation of blood coagulation is the plasma glycoprotein, tissue factor pathway inhibitor (TFPI). TFPI inhibits factor Xa and factor VIIa/tissue factor complex, thereby dampens the proteolytic cascade of the tissue fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d63a91b1a7cde4c902e99297dfc5666e
https://pubmed.ncbi.nlm.nih.gov/9759622
https://pubmed.ncbi.nlm.nih.gov/9759622
Publikováno v:
Thrombosis and haemostasis. 80(2)
Tissue factor:factor VIIa induced activation of blood coagulation is inhibited by the complex between factor Xa and tissue factor pathway inhibitor (factor Xa:TFPI). We recently reported that phospholipid-bound factor Xa reduces the high binding affi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e7f5f6114e463a625491292e0da43ce
https://pubmed.ncbi.nlm.nih.gov/9716152
https://pubmed.ncbi.nlm.nih.gov/9716152
Autor:
P. Zoldhelyi, P.M. Dillard, Janice McNatt, James T. Willerson, T.-C. Wun, T. Reese, Harnath Shelat
Publikováno v:
Journal of the American College of Cardiology. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4254b765ecc4833316d6b46dc5733c2
Publikováno v:
Blood. 87(6)
Activation of factor X by both the unactivated tissue factor:factor VII complex (TF:VII) and the activated tissue factor:factor VIIa complex (TF:VIIa) has been studied in the presence of tissue factor pathway inhibitor (TFPI), antithrombin III (ATIII
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac857c7b137040d51c6ee2d71b01c2d7
https://pubmed.ncbi.nlm.nih.gov/8630391
https://pubmed.ncbi.nlm.nih.gov/8630391
Publikováno v:
Thrombosis and haemostasis. 73(1)
Tissue factor pathway inhibitor, TFPI, has been shown to be highly effective as a topically applied antithrombotic in an arterial model of vascular thrombosis. To elucidate the mechanism and site of TFPI action, recombinant TFPI was conjugated to 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35f1fee3cc3b19212a8c8f30f78bb510
https://pubmed.ncbi.nlm.nih.gov/7740496
https://pubmed.ncbi.nlm.nih.gov/7740496
Autor:
C, Carr, G S, Bild, A C, Chang, G T, Peer, M O, Palmier, R B, Frazier, M E, Gustafson, T C, Wun, A A, Creasey, L B, Hinshaw
Publikováno v:
Circulatory shock. 44(3)
Excessive coagulation is a typical response to the vascular injury occurring in gram negative sepsis. This study evaluated the pharmacological effects of the use of a recombinant Escherichia coli derived form of tissue factor pathway inhibitor (ala-T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ddf71b4f8544f2b36319ca8186e9235
https://pubmed.ncbi.nlm.nih.gov/7600636
https://pubmed.ncbi.nlm.nih.gov/7600636