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pro vyhledávání: '"T C, Islam"'
Autor:
T C, Islam, C I, Smith
Publikováno v:
Immunological reviews. 178
Bruton's agammaglobulinemia tyrosine kinase (Btk) was identified as the gene mutated in X-linked agammaglobulinemia. Btk is involved in B-cell receptor signaling and B cell ontogeny as the disease is characterized by a block in B-cell development. Ce
Publikováno v:
The British journal of dermatology. 143(4)
Apoptosis is a genetically controlled process linked to growth and differentiation, involving specific molecular and cellular events activated as a result of a variety of internal and external stimuli.To examine the ability of physiological and synth
Publikováno v:
The journal of gene medicine. 2(3)
It has been shown previously that mutations in the cytoplasmic protein kinase, Bruton's tyrosine kinase (BTK) lead to X-linked agammaglobulinemia, an inherited primary immunodeficiency, thus making it a potential candidate for gene therapy.Producer c
Autor:
B F, Nore, L, Vargas, A J, Mohamed, L J, Brandén, C M, Bäckesjö, T C, Islam, P T, Mattsson, K, Hultenby, B, Christensson, C I, Smith
Publikováno v:
European journal of immunology. 30(1)
Bruton's tyrosine kinase (Btk) is a member of the Tec family of protein tyrosine kinases (PTK) characterized by an N-terminal pleckstrin homology domain (PH) thought to directly interact with phosphoinositides. We report here that wild-type (wt) and
Publikováno v:
The Journal of biological chemistry. 268(5)
The characterization of retinoic acid (RA)-regulated gene transcription in keratinocytes has important implications as to the function of retinoids in epidermal homeostasis and to the central role retinoids play in the pharmaco-therapy of a variety o