Zobrazeno 1 - 8
of 8
pro vyhledávání: '"T C, Dickson"'
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Brain penetrant microtubule stabilising agents (MSAs) are being increasingly validated as potential therapeutic strategies for neurodegenerative diseases and traumatic injuries of the nervous system. MSAs are historically used to treat malig
Externí odkaz:
https://doaj.org/article/4bdba742d30049b0b11e7bf02dd84e9c
Autor:
J A, Clark, C A, Blizzard, M C, Breslin, E J, Yeaman, K M, Lee, J A, Chuckowree, T C, Dickson
Publikováno v:
Neuropathology and applied neurobiology. 44(6)
Degeneration of the distal neuromuscular circuitry is a hallmark pathology of Amyotrophic Lateral Sclerosis (ALS). The potential for microtubule dysfunction to be a critical pathophysiological mechanism in the destruction of this circuitry is increas
Autor:
A E, King, T C, Dickson, C A, Blizzard, S S, Foster, R S, Chung, A K, West, M I, Chuah, J C, Vickers
Publikováno v:
The European journal of neuroscience. 26(8)
Excitotoxicity has been implicated as a potential cause of neuronal degeneration in amyotrophic lateral sclerosis (ALS). It has not been clear how excitotoxic injury leads to the hallmark pathological changes of ALS, such as the abnormal accumulation
Publikováno v:
The European journal of neuroscience. 26(5)
While long-distance regeneration may be limited in mammalian species, it is becoming apparent that damaged mature neurons retain some capacity for attempted regeneration and that the adult CNS is not entirely inhibitory to axon growth. Our investigat
Autor:
T. C. Dickson
Publikováno v:
Journal of the American Society for Naval Engineers. 37:222-223
Publikováno v:
Neuroreport. 8(7)
We investigated the reactive cytoskeletal changes following physical damage to axons in the rodent neocortex and compared these with the earliest neuronal alterations seen in Alzheimer's disease (AD). Insertion of a 25 gauge needle into the rodent so
Autor:
E B, Daniels, T C, Dickson
Publikováno v:
Healthcare financial management : journal of the Healthcare Financial Management Association. 44(2)
Geriatric outpatient clinics offer a way for healthcare providers to add Medicare patients and better manage their care. Opening a new clinic, however, requires a substantial commitment from hospital executives and a sizable investment, sometimes inc
Autor:
T. C. Dickson
Publikováno v:
The American Mathematical Monthly. 10:115