Výsledky vyhledávání - "T C, Chambers"

Akademický článek

Phorbol ester-induced low density lipoprotein receptor gene expression in HepG2 cells involves protein kinase C-mediated p42/44 MAP kinase activation

Autor: A Kumar, T C Chambers, B A Cloud-Heflin, K D Mehta

Publikováno v: Journal of Lipid Research, Vol 38, Iss 11, Pp 2240-2248 (1997)

The signaling pathway involved in low density lipoprotein (LDL) receptor gene expression induced by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) was investigated in the human hepatoma HepG2 cell line. Treatment of HepG2 cells with 100

Externí odkaz: https://doaj.org/article/dceb4f83e31b424bbf05c761c2697f6a

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TheBlechnum procerum('capense') (Blechnaceae) complex in New Zealand

Autor: T. C. Chambers, P. A. Farrant

Publikováno v: New Zealand Journal of Botany. 36:1-19

There are four species of Blechnum in the B. procerum complex in New Zealand: B. procerum and three new species, B. novae‐zelandiae, B. montanum, and B. triangularifolium. All three are distinct from the Australian B. minus. The new species are end

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::89e5762dd8f3275fce4904e4dc2e6881
https://doi.org/10.1080/0028825x.1998.9512544

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Blechnum blechnoides(Bory) Keys, (Blechnaceae), formerlyB. banksii(Hook.f.) mett. ex diels, a fern from salt-spray habitats of New Zealand and Chile

Autor: T. C. Chambers, P. A. Farrant

Publikováno v: New Zealand Journal of Botany. 34:441-445

The salt-spray fern found in coastal locations of New Zealand, formerly known as Blechnum banksii, is conspecific with the species that occurs on the coast of Chile, where it has been referred to as B. blechnoides and B. leyboldtianum. The specific n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::583be1b3128ab7a012e8b97b440a191f
https://doi.org/10.1080/0028825x.1996.10410125

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Molecular analysis of the multidrug transporter, P-glycoprotein

Autor: U A, Germann, T C, Chambers

Publikováno v: Cytotechnology. 27(1-3)

Inherent or acquired resistance of tumor cells to cytotoxic drugs represents a major limitation to the successful chemotherapeutic treatment of cancer. During the past three decades dramatic progress has been made in the understanding of the molecula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a120518b2b78b9a4eed58e83bb962d13
https://pubmed.ncbi.nlm.nih.gov/19002782

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AP-1 activation and altered AP-1 composition in association with increased phosphorylation and expression of specific Jun and Fos family proteins induced by vinblastine in KB-3 cells

Autor: A, Berry, M, Goodwin, C L, Moran, T C, Chambers

Publikováno v: Biochemical pharmacology. 62(5)

Vinblastine and other microtubule inhibitors are important antitumor agents that cause mitotic arrest, and induce apoptosis through poorly understood mechanisms, in a wide variety of cell lines. The activating protein 1 (AP-1) transcription factor is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f42fdff72db2200ba8de4b61919f02c8
https://pubmed.ncbi.nlm.nih.gov/11585055

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The c-Jun NH(2)-terminal protein kinase/AP-1 pathway is required for efficient apoptosis induced by vinblastine

Autor: M, Fan, M E, Goodwin, M J, Birrer, T C, Chambers

Publikováno v: Cancer research. 61(11)

Vinblastine is an important antitumor agent that induces G(2)-M arrest and subsequent apoptosis in a wide variety of cell lines, but the molecular mechanisms that link mitotic arrest and apoptosis are poorly understood. The AP-1 transcription factor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ea163e224ee7f5bfd243d21b9e6090f0
https://pubmed.ncbi.nlm.nih.gov/11389075

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Modulation of mitogen-activated protein kinases and phosphorylation of Bcl-2 by vinblastine represent persistent forms of normal fluctuations at G2-M1

Autor: M, Fan, L, Du, A A, Stone, K M, Gilbert, T C, Chambers

Publikováno v: Cancer research. 60(22)

Microtubule inhibitors, widely used in cancer chemotherapy, induce G2-M arrest and apoptosis and have in common the ability to stimulate Raf-1/Bcl-2 phosphorylation and activate c-Jun NH2-terminal protein kinase (JNK). These signal transduction pathw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ee143e4ede87f9aaab9e349c73af8d13
https://pubmed.ncbi.nlm.nih.gov/11103805

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Differential phosphorylation of sites in the linker region of P-glycoprotein by protein kinase C isozymes alpha, betaI, betaII, gamma, delta, epsilon, eta, and zeta

Autor: C W, Sachs, T C, Chambers, R L, Fine

Publikováno v: Biochemical pharmacology. 58(10)

To determine whether individual protein kinase C (PKC) isozymes differentially phosphorylate sites in the linker region of human P-glycoprotein (P-gp), we used a synthetic peptide substrate, PG-2, exactly corresponding to amino acid residues spanning

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::72a4b4c5c2d5c4606d28a3bacb9f63bd
https://pubmed.ncbi.nlm.nih.gov/10535749

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