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pro vyhledávání: '"T Brett Kothe"'
Autor:
T Brett Kothe, Emily Royse, Matthew W Kemp, Haruo Usuda, Masatoshi Saito, Gabrielle C Musk, Alan H Jobe, Noah H Hillman
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200713 (2018)
BACKGROUND:Epidermal growth factor receptor (EGFR) is important for airway branching and lung maturation. Mechanical ventilation of preterm lambs causes increases in EGFR and EGFR ligand mRNA in the lung. Abnormal EGFR signaling may contribute to the
Externí odkaz:
https://doaj.org/article/61e36e862b064d2888f243d5eaf88c36
Autor:
Samantha A. Becker, T. Brett Kothe, Justin B. Josephsen, Kathryn Jackson, Howard L. Williams, Noah H. Hillman
Publikováno v:
Neonatology. 119:474-482
Background: The combination of surfactant and budesonide has been shown to decrease BPD rates and severity. Budesonide may be released systemically from lungs, and the effects on the immature adrenal glands are not known. Objective: The aim of this s
Autor:
Howard L. Williams, T Brett Kothe, Connie D. Anderson, F Sadiq, Justin B. Josephsen, Nikki Burleyson, Noah H. Hillman
Publikováno v:
Journal of Perinatology
Background The addition of budesonide to surfactant in very-low-birth-weight infants with less severe RDS decreased bronchopulmonary dysplasia (BPD) severity. Long-term neurodevelopmental follow-up was needed to monitor for systemic effects of budeso
Autor:
Howard L. Williams, Nikki Burleyson, Connie D. Anderson, F Sadiq, Noah H. Hillman, T Brett Kothe
Publikováno v:
Pediatric Research. 87:940-945
In preterm infants on moderately high ventilator support, the addition of budesonide to surfactant lowered bronchopulmonary dysplasia (BPD) rates by 20% without increased morbidity or mortality. The aim of this cohort comparison was to determine the
Autor:
Erin L. Fee, Alan H. Jobe, Fabrizio Salomone, Noah H. Hillman, Augusto F. Schmidt, Matthew W. Kemp, Michael W. Clarke, T Brett Kothe, Gabrielle C. Musk, Emily Royse
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Mechanical ventilation from birth with normal tidal volumes (VT) causes lung injury and systemic responses in preterm sheep. The addition of budesonide to surfactant therapy decreases these injury markers. Budesonide and surfactant will decrease the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b937c5f3fbf65afcd5a7a07046b2c0
https://europepmc.org/articles/PMC6985873/
https://europepmc.org/articles/PMC6985873/
Autor:
T Brett, Kothe, Farouk H, Sadiq, Nikki, Burleyson, Howard L, Williams, Connie, Anderson, Noah H, Hillman
Publikováno v:
Pediatric research. 87(5)
In preterm infants on moderately high ventilator support, the addition of budesonide to surfactant lowered bronchopulmonary dysplasia (BPD) rates by 20% without increased morbidity or mortality. The aim of this cohort comparison was to determine the
Autor:
Gabrielle C. Musk, Augusto F. Schmidt, Alan H. Jobe, Fabrizio Salomone, Emily Royse, Michael W. Clarke, T Brett Kothe, Matthew W. Kemp, Noah H. Hillman
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Mechanical ventilation with normal tidal volumes (VT) causes lung and systemic inflammation in preterm sheep. Mechanical ventilation is associated with bronchopulmonary dysplasia (BPD) in preterm infants, and the addition of budesonide to surfactant
Autor:
Masatoshi Saito, Alan H. Jobe, Gabrielle C. Musk, Emily Royse, Haruo Usuda, Augusto F. Schmidt, Matthew W. Kemp, Noah H. Hillman, Fabrizio Salomone, Shimpei Watanabe, T Brett Kothe
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 315(2)
Mechanical ventilation causes lung injury and systemic inflammatory responses in preterm sheep and is associated with bronchopulmonary dysplasia (BPD) in preterm infants. Budesonide added to surfactant decreased BPD by 20% in infants. We wanted to de
Autor:
Alan H. Jobe, T Brett Kothe, Haruo Usuda, Noah H. Hillman, Masatoshi Saito, Emily Royse, Gabrielle C. Musk, Matthew W. Kemp
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200713 (2018)
PLoS ONE
PLoS ONE
Background Epidermal growth factor receptor (EGFR) is important for airway branching and lung maturation. Mechanical ventilation of preterm lambs causes increases in EGFR and EGFR ligand mRNA in the lung. Abnormal EGFR signaling may contribute to the
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