Zobrazeno 1 - 10
of 88
pro vyhledávání: '"T B, Cooper"'
Publikováno v:
Clinical Chemistry. 38:1756-1761
We determined fluoxetine (Prozac) and its major metabolite norfluoxetine in plasma by liquid chromatography with fluorescence detection. After liquid-liquid extraction from 1 mL of plasma, the extract was derivatized at room temperature with dansyl c
Autor:
Peter A. M. Auld, Praveen Ballabh, Alfred N. Krauss, I. Zervoudakis, T. B. Cooper, Jaishree Kumari, E. S. Lo
Publikováno v:
Clinical pharmacology and therapeutics. 71(1)
Objective The aims of the study were to compare the pharmacokinetics of betamethasone in singleton pregnancy with the pharmacokinetics in twin pregnancy and to assess the adrenal suppression produced by betamethasone. Study Design We measured serial
Autor:
L A, Mooney, F P, Perera, A M, Van Bennekum, W S, Blaner, J, Karkoszka, L, Covey, Y, Hsu, T B, Cooper, K, Frenkel
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10(6)
Oxidative DNA damage and antibodies to that damage have been implicated in lung, breast, and colorectal cancer. In this observational validation study, the relationship between anti-5-hydroxymethyl-2'-deoxyuridine (HMdU) autoantibody (aAb) and plasma
Publikováno v:
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 8(2)
The authors conducted a randomized, double-blind, 10-week clinical trial of two doses of nortriptyline in eight nursing homes. Sixty-nine patients, average age 79.5 years, were randomized to receive regular doses (60 mg-80 mg/day) vs. low doses (10 m
Publikováno v:
Neurochemical research. 24(11)
Cotinine is the major metabolite of nicotine. Nicotine is rapidly metabolized and has a short half-life, but cotinine is metabolized and eliminated at a much lower rate. Because of the resulting increase with time in the cotinine to nicotine ratio in
Publikováno v:
Journal of exposure analysis and environmental epidemiology. 8(3)
Adverse effects of maternal smoking have been mostly identified through epidemiologic investigations that have used questionnaires to assess active and passive smoking. However, unvalidated self-reports of cigarette smoking may bias true estimates of
Publikováno v:
Alcoholism, clinical and experimental research. 21(7)
Human neuroblastoma cells were exposed to ethanol (EtOH; 100 mM) in culture for various time periods. It was found that chronic EtOH exposure increased the arachidonyl-specific phospholipase A2 (PLA2) activity significantly in both cytosol (1.6-fold)
Publikováno v:
Biomedical chromatography : BMC. 11(3)
A coupled achiral-chiral stationary phase liquid chromatographic technique was developed to separate and quantitate the enantiomers of the phenylmorpholinol metabolite (2) of the antidepressant bupropion (1) in human plasma. At the retention time of
Publikováno v:
Przeglad epidemiologiczny. 51(1-2)
The purpose of the paper was to assess the validity of the self-reported tobacco smoke exposure in pregnancy against plasma cotinine measurements. A total of 158 patients from obstetrical wards was included in the cotinine study. Biochemical smokers
Publikováno v:
Psychopharmacology bulletin. 32(1)
Double-blind haloperidol was administered during two consecutive 3-week periods to 65 patients with acutely exacerbating schizophrenia or schizoaffective disorder. Two plasma levels were targeted. low (2 ng/mL) and moderate (10 ng/mL). The subjects w