Zobrazeno 1 - 10
of 45
pro vyhledávání: '"T Ashton Cropp"'
Autor:
Clinton A. L. McFeely, Bipasana Shakya, Chelsea A. Makovsky, Aidan K. Haney, T. Ashton Cropp, Matthew C. T. Hartman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Genetic code expansion (GCE) offers many exciting opportunities for the creation of synthetic organisms and for drug discovery methods that utilize in vitro translation. One type of GCE, sense codon reassignment (SCR), focuses on breaking th
Externí odkaz:
https://doaj.org/article/8fac6733bce441ee8239a9a3fc923092
Autor:
Jenny W. Cheung, William D. Kinney, Joshua S. Wesalo, Megan Reed, Eve M. Nicholson, Alexander Deiters, T. Ashton Cropp
Publikováno v:
ChemBioChem. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c0573fd004094da2f626e349466638c
https://doi.org/10.1002/cbic.202200721
https://doi.org/10.1002/cbic.202200721
Publikováno v:
ACS Synth Biol
Clarithromycin is an improved semi-synthetic analogue of the naturally occurring macrolide, erythromycin. The subtle modification of a methyl group on the C-6 hydroxyl group endows the molecule with improved acid stability and results in a clinically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141a03f6306629a94b18ebc4e7f60d9a
https://doi.org/10.1021/acssynbio.1c00151
https://doi.org/10.1021/acssynbio.1c00151
Autor:
Jayani A. Christopher, Sahan A. Galbada Liyanage, Eve M. Nicholson, William D. Kinney, T. Ashton Cropp
Publikováno v:
RSC Advances. 12:34142-34144
Here we report the synthesis and genetic encoding of the lysine post translational modifications, β-hydroxybutyryl-lysine, isobutyryl-lysine and isovaleryl-lysine. The ability to obtain a homogenous protein samples with site-specific incorporation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33658d752abe59803f8fa7cfe84c0994
https://doi.org/10.1039/d2ra04898a
https://doi.org/10.1039/d2ra04898a
Autor:
Han Zhou, Tomaya Carpenter, Xuan Fu, Bo Jin, Britton Ody, Mohammad Sazid Hassan, Savannah E. Jacobs, Jenny Cheung, Eve M. Nicholson, Mark Turlington, Bo Zhao, Sonja Lorenz, T. Ashton Cropp, Jun Yin
Publikováno v:
ChemBioChem. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e52fa9ff3b9c41ad74cd7c47ce01153
https://doi.org/10.1002/cbic.202200226
https://doi.org/10.1002/cbic.202200226
Autor:
Han Zhou, Tomaya Carpenter, Xuan Fu, Bo Jin, Britton Ody, Mohammad Sazid Hassan, Savannah E. Jacobs, Jenny Cheung, Eve M. Nicholson, Mark Turlington, Bo Zhao, Sonja Lorenz, T. Ashton Cropp, Jun Yin
Publikováno v:
Chembiochem
Di-ubiquitin (diUB) conjugates of defined linkages are useful tools to probe the functions of UB ligases, UB-binding proteins and deubiquitinating enzymes (DUBs) in coding, decoding and editing the signals carried by the UB chains. Here we developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6471e46d8d79a879936afcc31eb607c8
https://pubmed.ncbi.nlm.nih.gov/35567288
https://pubmed.ncbi.nlm.nih.gov/35567288
Publikováno v:
Organic & Biomolecular Chemistry. 15:4536-4539
Due to the lowered pKa of 4-fluorohistidine relative to histidine, peptides and proteins containing this amino acid are potentially endowed with novel properties. We report here the optimized synthesis of 4-fluorohistidine and show that it can effici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1f3d6e517637269b82cf79ae8457f2
https://doi.org/10.1039/c7ob00844a
https://doi.org/10.1039/c7ob00844a
Ubiquitin-mediated signaling pathways regulate essentially every aspect of cell biology in eukaryotes. Ubiquitin receptors typically contain ubiquitin-binding domains (UBDs) that have the ability to recognize monomeric ubiquitin (Ub) and polymeric Ub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf786914a1fad94d3ce3d974d9cea12
https://europepmc.org/articles/PMC6699165/
https://europepmc.org/articles/PMC6699165/
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