Zobrazeno 1 - 10
of 309
pro vyhledávání: '"T A Müller"'
Autor:
Jamie L. Adams, Tairmae Kangarloo, Yishu Gong, Vahe Khachadourian, Brian Tracey, Dmitri Volfson, Robert D. Latzman, Joshua Cosman, Jeremy Edgerton, David Anderson, Allen Best, Melissa A. Kostrzebski, Peggy Auinger, Peter Wilmot, Yvonne Pohlson, Stella Jensen-Roberts, Martijn L. T. M. Müller, Diane Stephenson, E. Ray Dorsey, the Parkinson Study Group Watch-PD Study Investigators and Collaborators
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Digital measures may provide objective, sensitive, real-world measures of disease progression in Parkinson’s disease (PD). However, multicenter longitudinal assessments of such measures are few. We recently demonstrated that baseline asses
Externí odkaz:
https://doaj.org/article/7b304f263c954a19b734d9277ee6190c
Publikováno v:
Frontiers in Systems Biology, Vol 4 (2024)
A rich pipeline of therapeutic candidates is advancing for Parkinson’s disease, many of which are targeting the underlying pathophysiology of disease. Emerging evidence grounded in novel genetics and biomarker discoveries is illuminating the true p
Externí odkaz:
https://doaj.org/article/f28f045c4f2845ea9ef9c8eca3076802
Autor:
J. T. I. Müller, B. Rattenbacher, K. Tell, C. Rösch, T. Welsch, M. Maurer, M. Sperl, M. Schnellenbach-Held
Publikováno v:
npj Microgravity, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Advances in space flight technology will enable the construction of Moon or even Mars bases in the not-too-distant future. Thus, materials will be needed that are suitable for building in microgravity environments. One idea is to use concret
Externí odkaz:
https://doaj.org/article/390af5f6345c4dbcba85bf3eab4b8212
Autor:
Short, P., Nicholl, M., Lawrence, A., Gomez, S., Arcavi, I., Wevers, T., Leloudas, G., Schulze, S., Anderson, J. P., Berger, E., Blanchard, P. K., Burke, J., Segura, N. Castro, Charalampopoulos, P., Chornock, R., Galbany, L., Gromadzki, M., Herzog, L. J., Hiramatsu, D., Horne, Keith, Hosseinzadeh, G., Howell, D. Andrew, Ihanec, N., Inserra, C., Kankare, E., Maguire, K., McCully, C., Bravo, T. E. Müller, Onori, F., Sollerman, J., Young, D. R.
We present results from spectroscopic observations of AT 2018hyz, a transient discovered by the ASAS-SN survey at an absolute magnitude of $M_V\sim -20.2$ mag, in the nucleus of a quiescent galaxy with strong Balmer absorption lines. AT 2018hyz shows
Externí odkaz:
http://arxiv.org/abs/2003.05470
Autor:
Elena S. Izmailova, R. Paul Maguire, Timothy J. McCarthy, Martijn L. T. M. Müller, Philip Murphy, Diane Stephenson
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 3, Pp 383-397 (2023)
Abstract The US Food and Drug Administration (FDA) has publicly recognized the importance of improving drug development efficiency, deeming translational biomarkers a top priority. The use of imaging biomarkers has been associated with increased rate
Externí odkaz:
https://doaj.org/article/280ee2cdd5ac4a9d8191db1ba81f6e17
Autor:
Haotian Zou, Varun Aggarwal, Glenn T. Stebbins, Martijn L. T. M. Müller, Jesse M. Cedarbaum, Anne Pedata, Diane Stephenson, Tanya Simuni, Sheng Luo
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 10, Pp 1382-1392 (2022)
Abstract The Movement Disorder Society revised version of the Unified Parkinson’s Disease Rating Scale (MDS‐UPDRS) parts 2 and 3 reflect patient‐reported functional impact and clinician‐reported severity of motor signs of Parkinson’s diseas
Externí odkaz:
https://doaj.org/article/ee3e3e53b9774dd6a46eb395e7981514
Autor:
George Roussos, Teresa Ruiz Herrero, Derek L. Hill, Ariel V. Dowling, Martijn L. T. M. Müller, Luc J. W. Evers, Jackson Burton, Adrian Derungs, Katherine Fisher, Krishna Praneeth Kilambi, Nitin Mehrotra, Roopal Bhatnagar, Sakshi Sardar, Diane Stephenson, Jamie L. Adams, E. Ray Dorsey, Josh Cosman
Publikováno v:
npj Digital Medicine, Vol 5, Iss 1, Pp 1-10 (2022)
Abstract Smartphones and wearables are widely recognised as the foundation for novel Digital Health Technologies (DHTs) for the clinical assessment of Parkinson’s disease. Yet, only limited progress has been made towards their regulatory acceptabil
Externí odkaz:
https://doaj.org/article/db03089d79b34210b7b6df5f8e088dd6
Autor:
Khiyam Hussain, Rena Liu, Rosanna C. G. Smith, Kri T. J. Müller, Mohammadmersad Ghorbani, Sofia Macari, Kirstie L. S. Cleary, Robert J. Oldham, Russell B. Foxall, Sonya James, Steven G. Booth, Tom Murray, Lekh N. Dahal, Chantal E. Hargreaves, Robert S. Kemp, Jemma Longley, James Douglas, Hannah Markham, Serena J. Chee, Richard J. Stopforth, Ali Roghanian, Matthew J. Carter, Christian H. Ottensmeier, Bjorn Frendéus, Ramsey I. Cutress, Ruth R. French, Martin J. Glennie, Jonathan C. Strefford, Stephen M. Thirdborough, Stephen A. Beers, Mark S. Cragg
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-32 (2022)
Abstract Background Hypoxia is a hallmark of the tumor microenvironment (TME) and in addition to altering metabolism in cancer cells, it transforms tumor-associated stromal cells. Within the tumor stromal cell compartment, tumor-associated macrophage
Externí odkaz:
https://doaj.org/article/4a2581bb496d4f649850cb54190883b9
Autor:
M. Pursiainen, G. Leloudas, S. Schulze, P. Charalampopoulos, C. R. Angus, J. P. Anderson, F. Bauer, T.-W. Chen, L. Galbany, M. Gromadzki, C. P. Gutiérrez, C. Inserra, J. Lyman, T. E. Müller-Bravo, M. Nicholl, S. J. Smartt, L. Tartaglia, P. Wiseman, D. R. Young
Publikováno v:
The Astrophysical Journal Letters, Vol 959, Iss 1, p L10 (2023)
SN 2023emq is a fast-evolving transient initially classified as a rare Type Icn supernova (SN), interacting with a H- and He-free circumstellar medium (CSM) around maximum light. Subsequent spectroscopy revealed the unambiguous emergence of narrow He
Externí odkaz:
https://doaj.org/article/b2387c258f9a449293de36f619415c14
Autor:
Shubham Srivastav, T. Moore, M. Nicholl, M. R. Magee, S. J. Smartt, M. D. Fulton, S. A. Sim, J. M. Pollin, L. Galbany, C. Inserra, A. Kozyreva, Takashi J. Moriya, F. P. Callan, X. Sheng, K. W. Smith, J. S. Sommer, J. P. Anderson, M. Deckers, M. Gromadzki, T. E. Müller-Bravo, G. Pignata, A. Rest, D. R. Young
Publikováno v:
The Astrophysical Journal Letters, Vol 956, Iss 2, p L34 (2023)
We present optical photometric and spectroscopic observations of the 02es-like type Ia supernova (SN) 2022ywc. The transient occurred in the outskirts of an elliptical host galaxy and showed a striking double-peaked light curve with an early excess f
Externí odkaz:
https://doaj.org/article/fc0161952c554de3a5563511b4151686