Zobrazeno 1 - 10
of 42
pro vyhledávání: '"T A, Kost"'
Publikováno v:
Bulletin of the Russian Academy of Sciences: Physics. 86:54-58
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f437b3fa7bb336cfba5cc3ced9fe12ed
https://doi.org/10.3103/s1062873822010166
https://doi.org/10.3103/s1062873822010166
Autor:
James F. Truax, J. Patrick Condreay, Jennings F. Worley, Christopher J. Apolito, T. A. Kost, Gang An, Jeffrey L. Pfohl
Publikováno v:
Receptors and Channels. 8:99-111
A variety of transfection approaches have been used to deliver plasmids encoding ion channel genes into cells. We have used the baculovirus transduction system, BacMam, to demonstrate transient expression of multi-subunit KATP channels in CHO-K1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14c6c702e77a5c196eef4afb362f061f
https://doi.org/10.3109/10606820212396
https://doi.org/10.3109/10606820212396
Autor:
Marcia L. Moss, I R Patel, A. G. Peranteau, G. Tian, Stephen V. Frye, Sue H. Kadwell, J. D. Stuart, L. K. Overton, Petr Kuzmic, T. A. Kost
Publikováno v:
Scopus-Elsevier
We have discovered that 17β-[N,N-(diethyl)carbamoyl]-6-azaandrost-4-en-3-one is a time-dependent inhibitor of type II 5α-reductase, as is the drug finasteride. Unlike finasteride, the 6-aza-steroid is not a time-dependent inhibitor of type I 5α-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c892d263df65a95906b65268cca172d
https://doi.org/10.1021/bi952472+
https://doi.org/10.1021/bi952472+
Autor:
G Chandra, J P Cogswell, L R Miller, M M Godlevski, S W Stinnett, S L Noel, S H Kadwell, T A Kost, J G Gray
Publikováno v:
The Journal of Immunology. 155:4535-4543
An intact cAMP response element (CRE) in the upstream regulatory sequence of IL-1 beta (-2755/-2762) has been shown to be essential for maintaining full IL-1 beta inducibility following treatment with LPS, PMA, or TNF-alpha. In the present study, usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7edbe2367764fd5ef761ed52b936b9f
https://doi.org/10.4049/jimmunol.155.10.4535
https://doi.org/10.4049/jimmunol.155.10.4535
Autor:
J J Lorenz, P J Furdon, J D Taylor, M W Verghese, G Chandra, T A Kost, S A Haneline, L A Roner, J G Gray
Publikováno v:
The Journal of Immunology. 155:836-844
IL-1 beta is a cytokine generally considered to be a major component involved in the pathogenesis of rheumatoid arthritis and other inflammatory diseases. Of the agents found in high concentrations in inflamed rheumatoid arthritis joints, TNF-alpha i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e1a5b3c25b85a81dbce33a6e3089cc9
https://doi.org/10.4049/jimmunol.155.2.836
https://doi.org/10.4049/jimmunol.155.2.836
Autor:
Sue H. Kadwell, Domanico Pl, J. D. Stuart, G. Tian, Marcia L. Moss, T. A. Kost, L. K. Overton, Robert A. Mook, I R Patel, H. N. Bramson
Publikováno v:
Biochemistry. 33:2291-2296
17 beta-(N-tert-butylcarbamoyl)-4-aza-5 alpha-androstan-1-en-3-one (finasteride), which has been approved for treatment of benign prostatic hyperplasia, is shown here to be a slow time-dependent inhibitor of human steroid 5 alpha-reductase isozyme 1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734895a64604489e39df0587cc4ba7af
https://doi.org/10.1021/bi00174a041
https://doi.org/10.1021/bi00174a041
Autor:
M. Bertrand, Alain Bernard, L. Overton, T. A. Kost, J. Young, C. Chabert, Catherine Cavegn, Z. Yahia-Cherif, A. Mills
Publikováno v:
Cytotechnology. 15:139-144
In this report, we compare two different expression systems: baculovirus/Sf9 and stable recombinant Drosophila Schneider 2 (S2) cell lines. The construction of a recombinant S2 cell line is simple and quick, and in batch fermentations the cells have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d398ce79619e4838ffe22b291de84f0d
https://doi.org/10.1007/bf00762388
https://doi.org/10.1007/bf00762388
Publikováno v:
Journal of Virology. 65:3276-3283
The CD4 molecule, a glycoprotein expressed primarily on the cell surface of specific T lymphocytes, is thought to function in T-cell antigen recognition and activation. In addition, CD4 serves as a receptor for human immunodeficiency virus type 1 (HI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f895882305b5cc62b3978b034919d90
https://doi.org/10.1128/jvi.65.6.3276-3283.1991
https://doi.org/10.1128/jvi.65.6.3276-3283.1991
Autor:
J D, Stuart, F W, Lee, D, Simpson Noel, S H, Kadwell, L K, Overton, C R, Hoffman, T A, Kost, T K, Tippin, R L, Yeager, K W, Batchelor, H N, Bramson
Publikováno v:
Biochemical pharmacology. 62(7)
The interaction of baculovirus expressed rat steroid 5alpha-reductase types 1 and 2 (r5AR1 and r5AR2) with 17beta-N-(2,5-bis(trifluoromethyl)phenyl)carbamoyl-4-aza-5alpha-androst-1-en-3-one (GI198745) was investigated at pH 7 and 37 degrees. This 5al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::74b67dc463dbf35e4e8f4311611baf45
https://pubmed.ncbi.nlm.nih.gov/11543729
https://pubmed.ncbi.nlm.nih.gov/11543729
Publikováno v:
Journal of virology. 75(2)
Our group and others have recently demonstrated the ability of recombinant baculoviruses to transduce mammalian cells at high frequency. To further characterize the use of baculovirus as a mammalian gene delivery system, we examined the status of tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4949ad171eedb8f9725823501c1473
https://pubmed.ncbi.nlm.nih.gov/11134303
https://pubmed.ncbi.nlm.nih.gov/11134303