Zobrazeno 1 - 8
of 8
pro vyhledávání: '"T A, Hultin"'
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 22(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31bd0be38de0a189ee6bd260800cb9a2
https://pubmed.ncbi.nlm.nih.gov/8149881
https://pubmed.ncbi.nlm.nih.gov/8149881
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 18(2)
The metabolism and disposition of N-(4-methoxyphenyl)-all-trans-retinamide (MPR), the major metabolite of N-(4-hydroxyphenyl)-all-trans-retinamide (4-HPR), were investigated in female B6D2F1 (BDF) mice. Following a single oral dose of 10 mg/kg, MPR d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a9330b2b2421666a7f596153892aa31
https://pubmed.ncbi.nlm.nih.gov/1971569
https://pubmed.ncbi.nlm.nih.gov/1971569
Publikováno v:
Biochemical Journal. 256:579-584
N-(4-Hydroxyphenyl)retinamide (4-HPR) is considered to be the most effective chemopreventive retinoid for chemically induced mammary carcinogenesis in rats. However, the mechanism of 4-HPR action in mammary cells is poorly understood. In the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e11b0555635ca8e8139ed534a910aa0
https://doi.org/10.1042/bj2560579
https://doi.org/10.1042/bj2560579
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 16(6)
The effects of pretreatment with N-(4-hydroxyphenyl)-all-trans-retinamide (4-HPR) and phenobarbital (PB) on the distribution and metabolism of 4-HPR, and on the levels of hepatic cytochromes, were investigated in female BDF mice. Pretreatment of mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5463424b907a3f246304cbc2e6425217
https://pubmed.ncbi.nlm.nih.gov/2907453
https://pubmed.ncbi.nlm.nih.gov/2907453
Autor:
T A, Hultin, W W, Weber
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 13(2)
Studies of genetically determined differences in arylamine acetylation with the model carcinogen 2-aminofluorene in C57BL/6J and A/J inbred mouse strains showed that individual differences in the pharmacokinetics of 2-aminofluorene were dependent on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0137f07c5fa7610f2b34e908c73a596b
https://pubmed.ncbi.nlm.nih.gov/2859160
https://pubmed.ncbi.nlm.nih.gov/2859160
Publikováno v:
Biochemical Society transactions. 12(1)
Acetylation, a major pathway for conjugation and excretion of foreign compounds, is a common route of arylamine biotransformation (Williams, 1959) and an important factor in the expression of mutagenic, carcinogenic and more acute effects of these su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da8231c3111bb77bce3c1833d8f375c
https://pubmed.ncbi.nlm.nih.gov/6705995
https://pubmed.ncbi.nlm.nih.gov/6705995
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 14(6)
The distribution of N-(4-hydroxyphenyl)-all-trans-retinamide (4-HPR) and its metabolites was investigated in the liver, serum, mammary gland, and urinary bladder of female rats and mice. Following an iv dose of 5 mg/kg to rats, 4-HPR distributed to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d1900f9c97cabd0aad9f8df0587a04f
https://pubmed.ncbi.nlm.nih.gov/2877832
https://pubmed.ncbi.nlm.nih.gov/2877832
Publikováno v:
Cancer research. 47(22)
The activity of dietary and topical administration of three retinoids, all-trans-retinoic acid, 13-cis-retinoic acid, and N-(4-hydroxyphenyl)retinamide (4-HPR), as promoters of skin tumor induction in SENCAR mice was studied. When administered as die
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9741c3b6df700f408a01f4e4b2a2e637
https://pubmed.ncbi.nlm.nih.gov/2959358
https://pubmed.ncbi.nlm.nih.gov/2959358