Výsledky vyhledávání - "T A, Haystead"

Rapid identification of protein phosphatase 1-binding proteins by mixed peptide sequencing and data base searching. Characterization of a novel holoenzymic form of protein phosphatase 1

Autor: C K, Damer, J, Partridge, W R, Pearson, T A, Haystead

Publikováno v: The Journal of biological chemistry. 273(38)

Microcystin-affinity chromatography was used to purify 15 protein phosphatase 1 (PP1)-binding proteins from the myofibrillar fraction of rabbit skeletal muscle. To reduce the time and amount of material required to identify these proteins, proteome a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6e11e563d1bf9c7e42eb723ee0c8c789
https://pubmed.ncbi.nlm.nih.gov/9733729

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Acceleration of myosin light chain dephosphorylation and relaxation of smooth muscle by telokin. Synergism with cyclic nucleotide-activated kinase

Autor: X, Wu, T A, Haystead, R K, Nakamoto, A V, Somlyo, A P, Somlyo

Publikováno v: The Journal of biological chemistry. 273(18)

Incorporation of 32P into telokin, a smooth muscle-specific, 17-18-kDa, acidic (pI 4.2-4.4) protein, was increased by forskolin (20 microM) in intact rabbit ileum smooth muscle (ileum) and by 8-bromo-cyclic GMP (100 microM) in alpha-toxin-permeabiliz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e5615f2cc8f530a26492b5b03dd5a595
https://pubmed.ncbi.nlm.nih.gov/9556631

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Purification and characterization of the mammalian myosin light chain phosphatase holoenzyme. The differential effects of the holoenzyme and its subunits on smooth muscle

Autor: A, Shirazi, K, Iizuka, P, Fadden, C, Mosse, A P, Somlyo, A V, Somlyo, T A, Haystead

Publikováno v: The Journal of biological chemistry. 269(50)

We have purified to homogeneity from the myofibrillar fraction of pig bladder a mammalian heterotrimeric form of PP-1, SMPP-1M. Purified pig bladder SMPP-1M is similar in composition and substrate specificity to avian gizzard PP-1M reported by Alessi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::497f71637131bd45daa0ff03a6494516
https://pubmed.ncbi.nlm.nih.gov/7989330

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Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase. Identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes

Autor: T A, Haystead, C M, Haystead, C, Hu, T A, Lin, J C, Lawrence

Publikováno v: The Journal of biological chemistry. 269(37)

PHAS-I is a heat- and acid-stable protein that is phosphorylated on Ser/Thr residues in response to insulin and growth factors. To investigate the phosphorylation of PHAS-I, the protein was expressed in bacteria and purified for use as substrate in p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0669a242b4d8118b3ef4b30cd10380d7
https://pubmed.ncbi.nlm.nih.gov/8083223

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Insulin activates a novel adipocyte mitogen-activated protein kinase kinase kinase that shows rapid phasic kinetics and is distinct from c-Raf

Autor: C M, Haystead, P, Gregory, A, Shirazi, P, Fadden, C, Mosse, P, Dent, T A, Haystead

Publikováno v: The Journal of biological chemistry. 269(17)

Treatment of adipocytes with insulin or phorbol 12-myristate 13-acetate (PMA) results in transient activation of mitogen-activated protein kinase kinase (MEK) (Tmax = 90 s) and mitogen-activated protein kinase (MAPK) (Tmax = 300 s). We have identifie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2575a80fb832aa31c76b7a858e466bca
https://pubmed.ncbi.nlm.nih.gov/8175693

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Functional expression of a MAP kinase kinase in COS cells and recognition by an anti-STE7/byr1 antibody

Autor: C M, Haystead, J, Wu, P, Gregory, T W, Sturgill, T A, Haystead

Publikováno v: FEBS letters. 317(1-2)

Mitogen-activated protein (MAP) kinases p42mapk and p44mapk are activated by dual tyrosine and threonine phosphorylation in vivo. Both MAPKs are phosphorylated and activated in vitro by an activator recently identified as a protein-tyrosine/threonine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2ebb0678a6737f93c75d43829b893dac
https://pubmed.ncbi.nlm.nih.gov/8428620

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Activation of messenger-independent protein kinases in wild-type and phorbol ester-resistant EL4 thymoma cells

Autor: K E, Meier, K A, Licciardi, T A, Haystead, E G, Krebs

Publikováno v: The Journal of biological chemistry. 266(3)

Phorbol esters, acting via activation of the protein kinase C family of protein serine/threonine kinases, are able to exert profound effects on various cellular functions. In this study, we used the EL4 thymoma cell line to study the potential role o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f92b48b5b8480e397558308810595106
https://pubmed.ncbi.nlm.nih.gov/1988454

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Okadaic acid mimics the action of insulin in stimulating protein kinase activity in isolated adipocytes. The role of protein phosphatase 2a in attenuation of the signal

Autor: T A, Haystead, J E, Weiel, D W, Litchfield, Y, Tsukitani, E H, Fischer, E G, Krebs

Publikováno v: The Journal of biological chemistry. 265(27)

Treatment of adipocytes with okadaic acid (a specific inhibitor of type 1 and 2a protein phosphatases) resulted in a rapid 8-10-fold stimulation of cell extract myelin basic protein (MBP) kinase activity (t1/2 = 10 min) and kinase activity toward a s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8b7bc4abcdfecadd0f4aa1eab4e625f8
https://pubmed.ncbi.nlm.nih.gov/2168895

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Epidermal growth factor alters metabolism of inositol lipids and activity of protein kinase C in mouse embryo palate mesenchyme cells

Autor: K P, Chepenik, T A, Haystead

Publikováno v: Journal of craniofacial genetics and developmental biology. 9(3)

Epidermal growth factor (EGF) stimulated mouse embryo palate mesenchyme (MEPM) cells (1) to incorporate [32P]O4(3-) into phosphatidylinositol (PI), phosphatidylcholine, and phosphatidic acid over a period of 60 min; 2) to incorporate [32P]O4(3-) into

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0aa218a4e93402e47dd21049b233e597
https://pubmed.ncbi.nlm.nih.gov/2613862

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