Zobrazeno 1 - 6
of 6
pro vyhledávání: '"T A, Berkhout"'
Publikováno v:
Journal of Lipid Research, Vol 26, Iss 8, Pp 964-969 (1985)
High density lipoprotein (HDL) from human serum was subfractionated into HDL2 and HDL3 by rate-zonal density gradient ultracentrifugation. The orientation of apoproteins (apo) A-I and A-II in these subfractions was investigated by use of the photosen
Externí odkaz:
https://doaj.org/article/e326a1d713d24fb9a61ec2ba9e269aee
Autor:
N J, Pearce, J W, Yates, T A, Berkhout, B, Jackson, D, Tew, H, Boyd, P, Camilleri, P, Sweeney, A D, Gribble, A, Shaw, P H, Groot
Publikováno v:
The Biochemical journal. 334
ATP citrate (pro-S)-lyase (EC 4.1.3.8), a cytosolic enzyme that generates acetyl-CoA for cholesterol and fatty acid synthesis de novo, is a potential target for hypolipidaemic intervention. Here we describe the biological effects of the inhibition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0eee92987658beaa9fe9c8357fadd5d
https://pubmed.ncbi.nlm.nih.gov/9693110
https://pubmed.ncbi.nlm.nih.gov/9693110
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(6)
Rat liver microsomal testosterone (250 microM) hydroxylation and immunoreactive CYP3A protein were compared after administration of the antiglucocorticoid RU 486 (50 mg.kg-1.day-1 for 4 days) and the hypocholesterolaemic drug SR-12813 (150 mg.kg-1.da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7210d512601d6ee8d1a9297b387d9262
https://pubmed.ncbi.nlm.nih.gov/9193879
https://pubmed.ncbi.nlm.nih.gov/9193879
Autor:
C R, Albrightson, P J, Bugelski, T A, Berkhout, B, Jackson, W D, Kerns, A J, Organ, A M, Badger
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 272(2)
Azaspiranes are novel immunomodulators which are effective in a variety of autoimmune diseases. One azaspirane analog, SKF 105685 (N,N-dimethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine dihydrochloride), caused a decrease in total serum chol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5dc8444badb84fb1c32f37cf64076198
https://pubmed.ncbi.nlm.nih.gov/7853183
https://pubmed.ncbi.nlm.nih.gov/7853183
Publikováno v:
The Journal of biological chemistry. 266(30)
A 32-carboxylic acid derivative of lanosterol (SKF 104976) was found to be a potent inhibitor of lanosterol 14 alpha-demethylase (14 alpha DM). 14 alpha DM activity in a Hep G2 cell extract was inhibited 50% by 2 nM SKF 104976. Exposure of intact cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a224986e3fb06aeb54773409ba5580c2
https://pubmed.ncbi.nlm.nih.gov/1657912
https://pubmed.ncbi.nlm.nih.gov/1657912
Publikováno v:
Cytochrome Systems ISBN: 9781461290780
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48d1349c9ff2d6c669f2cd2b9d9f757c
https://doi.org/10.1007/978-1-4613-1941-2_29
https://doi.org/10.1007/978-1-4613-1941-2_29
