Zobrazeno 1 - 10
of 5 248
pro vyhledávání: '"T {O'Brien}"'
Autor:
Qing Qi, Feng Deng, Rebecca Sammon, Karen Ritchie, Graciela Muniz-Terrera, Ivan Koychev, Paresh Malhotra, Siobhan Hutchinson, David Robinson, John T. O’Brien, Craig W. Ritchie, Brian Lawlor, Lorina Naci
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Females have a higher age-adjusted incidence of Alzheimer’s Disease (AD) than males, even when accounting for longer lifespan and, therefore, stand to benefit the most from dementia prevention efforts. As exposure to many modifi
Externí odkaz:
https://doaj.org/article/f444f2acc06b4074945bd1073a5c08c6
Autor:
Gemma Greenfinch, Calum A. Hamilton, Paul C. Donaghy, Michael Firbank, Nicola A. Barnett, Louise Allan, George S. Petrides, John-Paul Taylor, John T. O'Brien, Alan J. Thomas
Publikováno v:
BJPsych Open, Vol 10 (2024)
The aim of this study was to determine whether there was a significant change in cardiac [123I]-metaiodobenzylguanidine uptake between baseline and follow-up in individuals with mild cognitive impairment with Lewy bodies (MCI-LB) who had normal basel
Externí odkaz:
https://doaj.org/article/e519faefdb544755935a18184234e2cc
Autor:
Ning Ge, Rui Li, Min Liu, Wenxin Xia, Stephen T. O'Brien, Veronica McInerney, Joseph Galvin, Deirdre Ward, Catherine McGorrian, Timothy O'Brien, Sanbing Shen, Terence W. Prendiville
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 20 (2024)
Background Long‐QT syndrome is a primary cardiac ion channelopathy predisposing a patient to ventricular arrhythmia through delayed repolarization on the resting ECG. We aimed to establish a patient‐specific, human induced pluripotent stem cell (
Externí odkaz:
https://doaj.org/article/a5abb2f54b0f488792d176797764e91b
Autor:
Ashley Foret, Christopher B. Haaga Jr., Shivani Jain, Chelsea O. Baumgartner, Megan Escott, Benjamin R. Henderson, Sean T. O'Brien, Scott E. Delacroix Jr., Jessie R.R. Gills, Mary E. Westerman
Publikováno v:
International Brazilian Journal of Urology, Vol 50, Iss 3, Pp 277-286 (2024)
ABSTRACT Purpose: CT-guided MWA is a safe and effective tool that should be utilized in the treatment of small renal masses (SRMs). We aim to clarify the utility of CT-guided MWA by examining patient outcomes such as recurrence, treatment success, ch
Externí odkaz:
https://doaj.org/article/caaaefa7814741aa910e6fbba6a4be66
Autor:
Elijah Mak, Robert I. Reid, Scott A. Przybelski, Timothy G. Lesnick, Christopher G. Schwarz, Matthew L. Senjem, Sheelakumari Raghavan, Prashanthi Vemuri, Clifford R. Jack, Hoon Ki Min, Manoj K. Jain, Toji Miyagawa, Leah K. Forsberg, Julie A. Fields, Rodolfo Savica, Jonathan Graff-Radford, David T. Jones, Hugo Botha, Erik K. St. Louis, David S. Knopman, Vijay K. Ramanan, Dennis W. Dickson, Neill R. Graff-Radford, Tanis J. Ferman, Ronald C. Petersen, Val J. Lowe, Bradley F. Boeve, John T. O’Brien, Kejal Kantarci
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Dementia with Lewy bodies (DLB) is a neurodegenerative condition often co-occurring with Alzheimer’s disease (AD) pathology. Characterizing white matter tissue microstructure using Neurite Orientation Dispersion and Density Imaging (NODDI)
Externí odkaz:
https://doaj.org/article/149702719cdf4981a0894fd359d25ace
Autor:
Daniel T. O’Brien, Kimberly D. Lucas
Publikováno v:
Harvard Data Science Review, Vol 6, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/ab972f8a4c1549acbac7e2763bb794ef
Autor:
Samuel Gibbon, Audrey Low, Charlene Hamid, Megan Reid‐Schachter, Graciela Muniz‐Terrera, Craig W. Ritchie, Emanuele Trucco, Baljean Dhillon, John T. O'Brien, Thomas J. MacGillivray
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 3, Pp n/a-n/a (2024)
Abstract INTRODUCTION We tested associations between two retinal measures (optic disc pallor, peripapillary retinal nerve fiber layer [pRNFL] thickness) and four magnetic resonance imaging markers of cerebral small vessel disease (SVD; lacunes, micro
Externí odkaz:
https://doaj.org/article/006d8ce2e61e4c85bb65cafe6f2ab547
Autor:
Ingrid Buller-Peralta, Sarah Gregory, Audrey Low, Maria-Eleni Dounavi, Katie Bridgeman, Georgios Ntailianis, Brian Lawlor, Lorina Naci, Ivan Koychev, Paresh Malhotra, John T. O’Brien, Craig W. Ritchie, Graciela Muniz-Terrera
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract To date, there is a considerable heterogeneity of methods to score Allostatic Load (AL). Here we propose a comprehensive algorithm (ALCS) that integrates commonly used approaches to generate AL risk categories and assess associations to brai
Externí odkaz:
https://doaj.org/article/ccb535da1f184e7a9790aaf75a87d94a
Autor:
Lauren P. Giesler, William T. O'Brien, Georgia F. Symons, Sabrina Salberg, Gershon Spitz, Robb Wesselingh, Terence J. O'Brien, Richelle Mychasiuk, Sandy R. Shultz, Stuart J. McDonald
Publikováno v:
Neurotrauma Reports, Vol 5, Iss 1, Pp 74-80 (2024)
Traumatic brain injuries (TBIs) and concussions are prevalent in collision sports, and there is evidence that levels of exposure to such sports may increase the risk of neurological abnormalities. Elevated levels of fluid-based biomarkers have been o
Externí odkaz:
https://doaj.org/article/12b7caa5a7f249388a0e051cc18bdca7
Autor:
David J. Whiteside, Negin Holland, Kamen A. Tsvetanov, Elijah Mak, Maura Malpetti, George Savulich, P. Simon Jones, Michelle Naessens, Matthew A. Rouse, Tim D. Fryer, Young T. Hong, Franklin I. Aigbirhio, Eoin Mulroy, Kailash P. Bhatia, Timothy Rittman, John T. O’Brien, James B. Rowe
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract There is extensive synaptic loss from frontotemporal lobar degeneration, in preclinical models and human in vivo and post mortem studies. Understanding the consequences of synaptic loss for network function is important to support translatio
Externí odkaz:
https://doaj.org/article/ab6733cf5df64638bd28121108e81c94