Výsledky vyhledávání - "Türkan Koyuncuoğlu"

Akademický článek

Impact of Valproate and Levetiracetam Exposure on GAERS Behavior During Pregnancy

Autor: Melis Yavuz, Berk Can Kantarcı, Ahmet Şanlı, Şeyhmus Gavaş, Zehra Nur Turgan Aşık, Türkan Koyuncuoğlu, Özgür Kasımay, Filiz Onat

Publikováno v: Archives of Epilepsy, Vol 29, Iss 3, Pp 69-74 (2023)

Objective:Valproate (VPA) and levetiracetam (LEV) are frequently prescribed for the management of idiopathic generalized seizures; however, their well-documented teratogenic effects raise concerns when administered to pregnant epileptic patients. Thi

Externí odkaz: https://doaj.org/article/87154b32b78f4a33b6a3c30463dd5b7f

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Antioxidant and neuroprotective effects of dexpanthenol in rats induced with traumatic brain injury

Autor: Pınar Kuru Bektaşoğlu, Türkan Koyuncuoğlu, Dilan Özaydın, Cansu Kandemir, Dilek Akakın, Meral Yüksel, Bora Gürer, Erhan Çelikoğlu, Berrak Ç. Yeğen

Trauma-induced primary damage is followed by secondary damage, exacerbating traumatic brain injury (TBI). Dexpanthenol has been shown to protect tissues against oxidative damage in various inflammation models. This study aimed to investigate possible

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab29d1adaacd4a83237676f2e5f91011
https://hdl.handle.net/11424/286947

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Possible anti-inflammatory, antioxidant, and neuroprotective effects of apigenin in the setting of mild traumatic brain injury: an investigation*

Autor: Pınar Kuru Bektaşoğlu, Dilan Demir, Türkan Koyuncuoğlu, Meral Yüksel, İrem Peker Eyüboğlu, Ayça Karagöz Köroğlu, Dilek Akakın, Alper Yıldırım, Erhan Çelikoğlu, Bora Gürer

Objective: Apigenin is a plant flavone proven with biological properties such as anti-inflammatory, antioxidant, and antimicrobial effects. This study, it was aimed to examine the possible anti-inflammatory, antioxidant, and neuroprotective effects o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f633eeb586621c0bebb4303e8fe48b37
https://hdl.handle.net/11424/282631

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High-fat Diet Enhances Gastric Contractility, but Abolishes Nesfatin-1-induced Inhibition of Gastric Emptying

Autor: Sevil Arabaci-Tamer, Ozlem Tugce Cilingir-Kaya, Ayça Karagöz Köroğlu, M. Yuksel, Zarife Nigar Ozdemir-Kumral, Berrak Ç. Yeğen, Türkan Koyuncuoğlu

Publikováno v: Journal of Neurogastroenterology and Motility

Neither HFD nor NES-1 changed methylcellulose emptying, but NES-1 delayed saline emptying in cannulated ND-rats. Inhibitory effect of NES-1 on gastric emptying in ND-rats was reversed by all antagonists, and abolished in HFD-rats. In HFD-rats, carbac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7804195b84412812974894461720ac7
http://europepmc.org/articles/PMC8026381

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Nesfatin-1 ameliorates oxidative bowel injury in rats with necrotizing enterocolitis: The role of the microbiota composition and claudin-3 expression

Autor: Damla Yağmur, Türkan Koyuncuoğlu, Burak Aksu, Berrak Ç. Yeğen, Mustafa Akkiprik, E. Tolga Dagli, İrem Peker Eyüboğlu, Serap Sirvanci, Kıvılcım Karadeniz Cerit

Publikováno v: Journal of Pediatric Surgery. 55:2797-2810

Background and Purpose Ongoing high mortality due to necrotizing enterocolitis (NEC) necessitates the investigation of novel treatments to improve the outcome of the affected newborns. The aim was to elucidate the potential therapeutic impact of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c503b2bd7dcb91ec44856770f36300c8
https://doi.org/10.1016/j.jpedsurg.2020.02.025

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Neuroprotective Effect of Cinnamaldehyde on Secondary Brain Injury After Traumatic Brain Injury in a Rat Model

Autor: Türkan Koyuncuoğlu, Meral Yüksel, Dilan Demir, Berrak Ç. Yeğen, Gizem Sucu, Dilek Akakin, Bora Gürer, İrem Peker Eyüboğlu, Erhan Celikoglu, Pınar Kuru Bektaşoğlu

Publikováno v: World neurosurgery. 153

Objective: The aim of this study was to investigate the possible neuroprotective effects of cinnamaldehyde (CA) on secondary brain injury after traumatic brain injury (TBI) in a rat model. Methods: Rats were randomly divided into 4 groups: control (n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14af315465f8f2c504845005c144a26a
https://pubmed.ncbi.nlm.nih.gov/34224887

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Oestrogen receptor ERα and ERβ agonists ameliorate oxidative brain injury and improve memory dysfunction in rats with an epileptic seizure

Autor: Can Erzik, Meral Yüksel, Ayça Karagöz, Berrak Ç. Yeğen, Dilek Akakin, Sevil Arabaci Tamer, Türkan Koyuncuoğlu

Publikováno v: Experimental Physiology. 104:1911-1928

New findings What is the central question of this study? Could different hormonally active substances, including oestrogen receptor (ER) agonists, protect against oxidative brain damage and memory impairment induced by a single epileptic seizure in r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43e7b6f1dabfacf638aa417faa875e3
https://doi.org/10.1113/ep087986

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Neuroprotective effects of mildronate in a rat model of traumatic brain injury

Autor: Dilek Akakin, Meral Yüksel, Türkan Koyuncuoğlu, Pınar Kuru Bektaşoğlu, Bora Gürer, Berrak Ç. Yeğen, Dilan Demir, Erhan Celikoglu, Cansu Kandemir

Publikováno v: Injury. 50:1586-1592

Traumatic brain injury (TBI) is one of the most common preventable causes of mortality and morbidity. Inflammation, apoptosis, oxidative stress, and ischemia are some of the important pathophysiological mechanisms underlying neuronal loss after TBI.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e408ae5069b943c60461d7d885d21a2
https://doi.org/10.1016/j.injury.2019.08.036

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Neuroprotective Effect of Plasminogen Activator Inhibitor-1 Antagonist in the Rat Model of Mild Traumatic Brain Injury

Autor: Meral Yüksel, Hizir Kurtel, Can Erzik, İrem Peker Eyüboğlu, Pınar Kuru Bektaşoğlu, Türkan Koyuncuoğlu, Dilek Akakin, Selin Akbulut

Publikováno v: Inflammation. 44(6)

Background: Plasminogen activator inhibitor-1 (PAI-1) antagonists are known for their neuroprotective effects. In this study, it was aimed to investigate the possible protective effects of PAI-1 antagonists in a rat mild traumatic brain injury (TBI)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476cf6197607045d3d0bd17e9806d59f
https://pubmed.ncbi.nlm.nih.gov/34460025

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High intensity interval training protects from Post Traumatic Stress Disorder induced cognitive impairment

Autor: Türkan Koyuncuoğlu, Özgür Kasimay Çakir, Ekin Kuntsal Dertsiz, Dilek Akakin, Meral Yüksel, Nurşen Çetrez, Zeynep Meral, Hacer Sevim, Berfin Gönenç

Publikováno v: Behavioural brain research. 397

This study aimed to show the possible protective effects of high intensity interval training (HIIT) in PTSD-induced rats and probable underlying mechanisms. Female rats (n = 44) were separated as; Sedentary (SED), moderate intensity continuous traini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c69686945697e7f905ffe62c3e5f0b
https://pubmed.ncbi.nlm.nih.gov/32976860

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