Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Tünde Praznovszky"'
Autor:
Anna Tóth, Katalin Fodor, Tünde Praznovszky, Vilmos Tubak, Andor Udvardy, Gyula Hadlaczky, Robert L Katona
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85565 (2014)
Mammalian artificial chromosomes are natural chromosome-based vectors that may carry a vast amount of genetic material in terms of both size and number. They are reasonably stable and segregate well in both mitosis and meiosis. A platform artificial
Externí odkaz:
https://doaj.org/article/f4273f10e4a3495b9e5d460d1935b20b
Autor:
Erika Csonka, Gyula Hadlaczky, Andor Udvardy, Tünde Praznovszky, J. Kereső, Imre Cserpán, K. Székely Szűcs, Barnabas Szakal, Robert L. Katona, Péter Blazsó, Ildikó Sinkó, Gy. Holló, Katalin Fodor
Publikováno v:
Cellular and Molecular Life Sciences. 65:3830-3838
Mammalian artificial chromosomes (MACs) are safe, stable, non-integrating genetic vectors with almost unlimited therapeutic transgene-carrying capacity. The combination of MAC and stem cell technologies offers a new strategy for stem cell-based thera
Autor:
Erika Csonka, Edit Novák, Robert L. Katona, Mónika Mórocz, Márta Rózsavölgyi, Imre Cserpán, Tünde Praznovszky, Gyula Hadlaczky, Katalin Fodor
Publikováno v:
Nucleic Acids Research. 30:2899-2905
We have investigated the large-scale organization of the human chAB4-related long-range multisequence family, a low copy-number repetitive DNA located in the pericentromeric heterochromatin of several human chromosomes. Analysis of genomic clones rev
Autor:
Robert L. Katona, Katalin Fodor, Tünde Praznovszky, Vilmos Tubak, Andor Udvardy, Anna Tóth, Gyula Hadlaczky, Péter Blazsó, Imre Cserpán
Publikováno v:
Acta biologica Hungarica. 65(3)
Direct reprogramming of mouse fibroblasts into induced pluripotent stem cells (iPS) was achieved recently by overexpression of four transcription factors encoded by retroviral vectors. Most of the virus vectors, however, may cause insertional mutagen
Autor:
Robert L. Katona, Tünde Praznovszky, Vilmos Tubak, Andor Udvardy, Anna Tóth, Gyula Hadlaczky, Katalin Fodor
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 1, p e85565 (2014)
PLoS ONE, Vol 9, Iss 1, p e85565 (2014)
Mammalian artificial chromosomes are natural chromosome-based vectors that may carry a vast amount of genetic material in terms of both size and number. They are reasonably stable and segregate well in both mitosis and meiosis. A platform artificial
Autor:
Carl Perez, Judit Keresö, Erika Csonka, Gyula Hadlaczky, Stephan Imreh, Håkan Telenius, Anna Szeles, Jan I. Drayer, Tünde Praznovszky, Alexisann Maxwell
Publikováno v:
Chromosome Research. 7:3-7
A 60-Mb murine chromosome consisting of murine pericentric satellite DNA and two bands of integrated marker and reporter genes has been generated de novo in a rodent/human hybrid cell line (mM2C1). This prototype mammalian artificial chromosome platf
Autor:
William H. R. Langridge, Tünde Praznovszky, Gyula Hadlaczky, Aladar A. Szalay, K. Illes, Károly Fátyol
Publikováno v:
Molecular and General Genetics MGG. 260:1-8
We have isolated a stably transformed Bormbyx mori cell line containing a novel selectable marker gene, puromycin N-acetyl transferase, under control of transcriptional regulatory signals from the A3 cytoplasmic actin gene. By using this cell line we
Autor:
Tünde Praznovszky, Erika Csonka, A. T. Sumner, Aladar A. Szalay, Imre Cserpán, Robert L. Katona, Gy. Hadlaczky, Katalin Fodor, Károly Fátyol, Gy. Holló, A. R. Ross, Judit Kereso, Anna Szeles
Publikováno v:
Chromosome Research. 4:226-239
Chromosomes formed de novo which originated from the centromeric region of mouse chromosome 7, have been analysed. These new chromosomes were formed by apparently similar large-scale amplification processes, and are organized into amplicons of approx
Publikováno v:
Acta biologica Hungarica. 63(1)
Cyclin C is a highly conserved protein that regulates cell-cycle, messenger RNA transcription and cell adhesion. Recently published studies demonstrate that this protein is an essential player during early embryonic development of multicellular eukar
Autor:
Tünde, Praznovszky
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 738
Mammalian satellite DNA-based artificial chromosomes (SATACs) are unique among the mammalian artificial chromosomes. These reproducibly generated de novo chromosomes are stably maintained in different species, readily purified from the host cell's ch