The Ubiquitin Ligase Adaptor NDFIP1 Interacts with TRESK and Negatively Regulates the Background K ⁺ Current.

Autor: Pergel E; Department of Physiology, Semmelweis University, 1094 Budapest, Hungary., Tóth DJ; Department of Physiology, Semmelweis University, 1094 Budapest, Hungary.; HUN-REN-SU Molecular Physiology Research Group, Hungarian Research Network and Semmelweis University, 1094 Budapest, Hungary., Baukál D; Department of Physiology, Semmelweis University, 1094 Budapest, Hungary., Veres I; Department of Physiology, Semmelweis University, 1094 Budapest, Hungary., Czirják G; Department of Physiology, Semmelweis University, 1094 Budapest, Hungary.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 15; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 15.

Computational drug repurposing against SARS-CoV-2 reveals plasma membrane cholesterol depletion as key factor of antiviral drug activity.

Autor: Barsi S; Semmelweis University, Faculty of Medicine, Department of Physiology, Budapest, Hungary., Papp H; National Laboratory of Virology, University of Pécs, Pécs, Hungary.; Institute of Biology, Faculty of Sciences, University of Pécs, Pécs, Hungary., Valdeolivas A; Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Bioquant, Heidelberg, Germany., Tóth DJ; Semmelweis University, Faculty of Medicine, Department of Physiology, Budapest, Hungary., Kuczmog A; National Laboratory of Virology, University of Pécs, Pécs, Hungary.; Institute of Biology, Faculty of Sciences, University of Pécs, Pécs, Hungary., Madai M; National Laboratory of Virology, University of Pécs, Pécs, Hungary.; Institute of Biology, Faculty of Sciences, University of Pécs, Pécs, Hungary., Hunyady L; Semmelweis University, Faculty of Medicine, Department of Physiology, Budapest, Hungary.; MTA-SE Laboratory of Molecular Physiology, Budapest, Hungary.; Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary., Várnai P; Semmelweis University, Faculty of Medicine, Department of Physiology, Budapest, Hungary.; MTA-SE Laboratory of Molecular Physiology, Budapest, Hungary., Saez-Rodriguez J; Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Bioquant, Heidelberg, Germany., Jakab F; National Laboratory of Virology, University of Pécs, Pécs, Hungary.; Institute of Biology, Faculty of Sciences, University of Pécs, Pécs, Hungary., Szalai B; Semmelweis University, Faculty of Medicine, Department of Physiology, Budapest, Hungary.

Publikováno v: PLoS computational biology [PLoS Comput Biol] 2022 Apr 11; Vol. 18 (4), pp. e1010021. Date of Electronic Publication: 2022 Apr 11 (Print Publication: 2022).

Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein.

Autor: Klima M; Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nam. 2., 16610 Prague 6, Czech Republic., Tóth DJ; Section on Molecular Signal Transduction, Program for Developmental Neuroscience, NICHD, NIH, Bethesda, MD 20892, USA., Hexnerova R; Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nam. 2., 16610 Prague 6, Czech Republic., Baumlova A; Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nam. 2., 16610 Prague 6, Czech Republic., Chalupska D; Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nam. 2., 16610 Prague 6, Czech Republic., Tykvart J; Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nam. 2., 16610 Prague 6, Czech Republic., Rezabkova L; Laboratory of Biomolecular Research, Department of Biology and Chemistry, Paul Scherrer Institute, 5232, Villigen PSI, Switzerland., Sengupta N; Section on Molecular Signal Transduction, Program for Developmental Neuroscience, NICHD, NIH, Bethesda, MD 20892, USA., Man P; Institute of Microbiology AS CR, v.v.i., Videnska 1083, Prague, Czech Republic.; Department of Biochemistry, Faculty of Science, Charles University in Prague, Hlavova 8, Prague, Czech Republic., Dubankova A; Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nam. 2., 16610 Prague 6, Czech Republic., Humpolickova J; Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nam. 2., 16610 Prague 6, Czech Republic., Nencka R; Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nam. 2., 16610 Prague 6, Czech Republic., Veverka V; Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nam. 2., 16610 Prague 6, Czech Republic., Balla T; Section on Molecular Signal Transduction, Program for Developmental Neuroscience, NICHD, NIH, Bethesda, MD 20892, USA., Boura E; Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nam. 2., 16610 Prague 6, Czech Republic.

Publikováno v: Scientific reports [Sci Rep] 2016 Mar 24; Vol. 6, pp. 23641. Date of Electronic Publication: 2016 Mar 24.

Measurement of inositol 1,4,5-trisphosphate in living cells using an improved set of resonance energy transfer-based biosensors.

Autor: Gulyás G; Department of Physiology, Faculty of Medicine, Semmelweis University, Budapest 1094, Hungary., Tóth JT; Department of Physiology, Faculty of Medicine, Semmelweis University, Budapest 1094, Hungary., Tóth DJ; Department of Physiology, Faculty of Medicine, Semmelweis University, Budapest 1094, Hungary., Kurucz I; Section on Molecular Signal Transduction, Program for Developmental Neuroscience, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, United States of America., Hunyady L; Department of Physiology, Faculty of Medicine, Semmelweis University, Budapest 1094, Hungary., Balla T; Section on Molecular Signal Transduction, Program for Developmental Neuroscience, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, United States of America., Várnai P; Department of Physiology, Faculty of Medicine, Semmelweis University, Budapest 1094, Hungary.

Publikováno v: PloS one [PLoS One] 2015 May 01; Vol. 10 (5), pp. e0125601. Date of Electronic Publication: 2015 May 01 (Print Publication: 2015).

Mapping of the localization of type 1 angiotensin receptor in membrane microdomains using bioluminescence resonance energy transfer-based sensors.

Autor: Balla A; Department of Physiology, Faculty of Medicine, Semmelweis University, Budapest, Hungary., Tóth DJ, Soltész-Katona E, Szakadáti G, Erdélyi LS, Várnai P, Hunyady L

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2012 Mar 16; Vol. 287 (12), pp. 9090-9. Date of Electronic Publication: 2012 Jan 30.