Zobrazeno 1 - 10
of 229
pro vyhledávání: '"T, Weimer"'
Autor:
Benedict M. Matern, Eric Spierings, Selle Bandstra, Abeer Madbouly, Stefan Schaub, Eric T. Weimer, Matthias Niemann
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionModern histocompatibility algorithms depend on the comparison and analysis of high-resolution HLA protein sequences and structures, especially when considering epitope-based algorithms, which aim to model the interactions involved in anti
Externí odkaz:
https://doaj.org/article/837d41c767274cfdaaea7944fce232b1
Allele-specific quantification of human leukocyte antigen transcript isoforms by nanopore sequencing
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionWhile tens of thousands of HLA alleles have been identified by DNA sequencing, the contribution of alternative splicing to HLA diversity is not well characterized. In this study, we sought to determine if long-read sequencing could be use
Externí odkaz:
https://doaj.org/article/17cffb73c6b64a13b5b7994fb83c165f
Autor:
Caleb Cornaby, Eric T Weimer
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0288743 (2023)
BackgroundHLA antibody testing is essential for successful solid-organ allocation, patient monitoring post-transplant, and risk assessment for both solid-organ and hematopoietic transplant patients. Luminex solid-phase testing is the most common meth
Externí odkaz:
https://doaj.org/article/02f1328b6c774b799dd21daeeb5f2466
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
HLA typing provides essential results for stem cell and solid organ transplants, as well as providing diagnostic benefits for various rheumatology, gastroenterology, neurology, and infectious diseases. It is becoming increasingly clear that understan
Externí odkaz:
https://doaj.org/article/7e197cf3e9f542c7be1f0b8b6c79631c
Autor:
Caleb Cornaby, Eric T. Weimer
Publikováno v:
Clinics in Laboratory Medicine. 42:603-612
Autor:
Chang Liu, Brian F Duffy, Eric T Weimer, Maureen C Montgomery, Jo-Ellen Jennemann, Rachel Hill, Donna Phelan, Lindsay Lay, Bijal A Parikh
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0232050 (2020)
BackgroundNext-generation sequencing (NGS) has enabled efficient high-resolution typing of human leukocyte antigen (HLA) genes with minimal ambiguity. Most commercially available assays amplify individual or subgroup of HLA genes by long-range PCR fo
Externí odkaz:
https://doaj.org/article/3017f4a8711249fc9be78dc01d0541b1
Autor:
Martin L. Buchkovich, Chad C. Brown, Kimberly Robasky, Shengjie Chai, Sharon Westfall, Benjamin G. Vincent, Eric T. Weimer, Jason G. Powers
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-15 (2017)
Abstract Background The human leukocyte antigen (HLA) system is a genomic region involved in regulating the human immune system by encoding cell membrane major histocompatibility complex (MHC) proteins that are responsible for self-recognition. Under
Externí odkaz:
https://doaj.org/article/e991dd965ccc46c98ddaccc12564b51c
Autor:
Jing Zhu, Tejendra Patel, Jordan A. Miller, Chad D. Torrice, Mehak Aggarwal, Margaret R. Sketch, Maurice D. Alexander, Paul M. Armistead, James M. Coghill, Tatjana Grgic, Katarzyna J. Jamieson, Jonathan R. Ptachcinski, Marcie L. Riches, Jonathan S. Serody, John L. Schmitz, J. Ryan Shaw, Thomas C. Shea, Oscar Suzuki, Benjamin G. Vincent, William A. Wood, Kamakshi V. Rao, Tim Wiltshire, Eric T. Weimer, Daniel J. Crona
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 858 (2020)
Tacrolimus exhibits high inter-patient pharmacokinetics (PK) variability, as well as a narrow therapeutic index, and therefore requires therapeutic drug monitoring. Germline mutations in cytochrome P450 isoforms 4 and 5 genes (CYP3A4/5) and the ATP-b
Externí odkaz:
https://doaj.org/article/3c55e94674f84324902c0900d35780ff
Akademický článek
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Autor:
Caleb Cornaby, Eric T. Weimer
Publikováno v:
Advances in Molecular Pathology. 3:199-205