Systemic versus free antibiotic delivery in preventing acute exogenous implant related infection in a rat model

Autor: Conrado Aparicio, Ramon B. Gustilo, Mats Bue, Andrew H. Schmidt, Richard F. Kyle, Ole Halfdan Larsen, Glen Hansen, Dean T. Tsukayama, Arick Sabin, Gudrun Mirick Mueller, Joan E. Bechtold, Scott B. Marston, Alexandra R. Armstrong, Bruce R. Lindgren

Publikováno v: Marston, S, Mueller, G M, Sabin, A, Hansen, G T, Lindgren, B, Aparicio, C, Armstrong, A R, Larsen, O H, Schmidt, A, Kyle, R, Gustilo, R, Tsukayama, D, Bechtold, J & Bue, M 2022, ' Systemic versus Free Antibiotic Delivery in Preventing Acute Exogenous Implant Related Infection in a Rat Model ', Journal of Orthopaedic Research, vol. 40, no. 2, pp. 429-438 . https://doi.org/10.1002/jor.25052

We studied systemic ceftriaxone, and free/local tobramycin and doxycycline in a controlled rat model representing a generic acute exogenous joint infection. We hypothesized that evidence of infection (quantitative colony forming units [CFU], qualitat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c77ead22978bc055c741cda41b1798
https://pubmed.ncbi.nlm.nih.gov/33913540

Acinetobacter baumannii is not Associated with Osteomyelitis in a Rat Model: A Pilot Study

Autor: Joan E. Bechtold, Stefan Collinet-Adler, Charles Gerald T. Ledonio, Carlos A. Castro, Dean T. Tsukayama

Publikováno v: Clinical Orthopaedics & Related Research. 469:274-282

Multidrug resistant Acinetobacter baumannii (MDR AB) with and without Staphylococcus aureus (SA) is a commonly isolated organism in infected segmental bone defects in combat-related trauma in Iraq and Afghanistan. Although MDR AB in visceral infectio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8aff320285fb9a2c1a9cd32ceb4472e
https://doi.org/10.1007/s11999-010-1488-0

Tuberculous Arthritis of the Knee Treated with Two-Stage Total Knee Arthroplasty

Autor: Lance E. LeClere, Keith G. Holley, Dean T. Tsukayama, V. Franklin Sechriest

Publikováno v: The Journal of Bone and Joint Surgery-American Volume. 91:186-191

It has been estimated that 2 billion people worldwide currently have tuberculosis in its latent form and that the active form of the disease will develop in 8 million people annually1. Tuberculous arthritis of the knee is one of the most common muscu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb22923990c48db5799e0712119a459
https://doi.org/10.2106/jbjs.g.01421

The evolution of Pseudomonas aeruginosa during antibiotic rotation in a medical intensive care unit: the RADAR-trial

Autor: B. Chmielewski, H.J van Loon, Jan Verhoef, C. Cartwright, Chr. van der Werken, A. C. Fluit, Dean T. Tsukayama

Publikováno v: International Journal of Antimicrobial Agents. 24:339-345

Bacterial spread between patients may contribute to the high prevalence of antibiotic-resistant pathogens within ICUs. The aim of this study was to evaluate the fate of Pseudomonas aeruginosa during the different antibiotic regimens. Susceptibility p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc144da2bde0d42797c18b5057b5cf7
https://doi.org/10.1016/j.ijantimicag.2004.04.011

Infection After Total Knee Arthroplasty. A Retrospective Study of the Treatment of Eighty-One Infections*

Autor: Douglas A. Becker, Hiroyuki Segawa, Richard F. Kyle, Ramon B. Gustilo, Dean T. Tsukayama

Publikováno v: The Journal of Bone & Joint Surgery. 81:1434-45

Background: The clinical presentation of an infection at the site of a total knee arthroplasty can be used as a guide to treatment, including the decision as to whether the prosthesis should be retained or removed. We reviewed the results of treatmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d0715dca63d923037e55f31652f7a0
https://doi.org/10.2106/00004623-199910000-00008