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Publikováno v:
International Journal of Food Sciences and Nutrition. 60:106-113
We studied the psychological stress-reducing effect of chocolate enriched with gamma-aminobutyric acid (GABA), on stress induced by an arithmetic task using changes of heart rate variability (HRV) and salivary chromogranin A (CgA). Subjects ingested
Autor:
T Takishima
Publikováno v:
JAPANES JOURNAL OF MEDICAL INSTRUMENTATION. 65:109-113
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 267:L152-L158
We examined the role of inositol 1,4,5-trisphosphate (IP3) receptors in acetylcholine (ACh)-induced chloride (Cl-) current in acinar cells of human and feline airway submucosal glands, using whole cell patch-clamp analysis. ACh (10 nM-1 microM) induc
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 267:L159-L164
The standard patch-clamp technique was employed on enzymatically digested acinar cells of submucosal glands isolated from feline trachea. ATP (-10(-3) M) evoked bidirectional current responses and an initial inward current at -80 mV (Cl- current) was
Autor:
Sanae Shimura, Masayuki Yamamoto, Tsuyoshi Sasaki, Kunio Shirato, T. Takishima, Hiroshi Okayama, Makoto Satoh
Publikováno v:
Respiration Physiology. 96:321-329
We examined the effect of Mg 2+ on potential difference (PD) and short circuit current (SCC) of the posterior epithelial membrane of canine trachea using an Ussing chamber. After the exchange to a Mg 2+ -free solution, PD and SCC rapidly increased, r
Autor:
T. Takishima, A. Igarashi, Hiroshi Inoue, Natsuko Nakajima, H. Yamauchi, Motohiko Miura, Tohru Takahashi, Masakazu Ichinose, Kunio Shirato
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 149:694-698
We examined the mechanisms of bradykinin-induced airway microvascular leakage in guinea pig airways by measuring extravasation of Evans blue dye. Animals were pretreated with propranolol (1 mg/kg, intravenous) and atropine (1 mg/kg, intravenous) to b
Autor:
Kunio Shirato, Jun Midorikawa, Jiang-Tao Lin, Michiko Okayama, Hiroshi Inoue, Then Shen, T. Takishima
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 149:76-80
To investigate whether increased release of acetylcholine may be involved in propranolol-induced bronchoconstriction (PIB), the inhibitory effect of pilocarpine (Pilo), an agonist of M2-muscarinic receptors that in 11 stable asthmatic subjects. The b
Publikováno v:
Respiration Physiology. 93:239-247
To determine the role of protein kinase C (PKC) in airway submucosal gland secretion, we examined the effect of a selective PKC stimulant, phorbol 12-myristate 13-acetate (PMA), on mucus glycoprotein (MGP) secretion, fluid secretion and intracellular