Zobrazeno 1 - 10
of 438
pro vyhledávání: '"T, Soler"'
RANK is a poor prognosis marker and a therapeutic target in ER‐negative postmenopausal breast cancer
Autor:
Marina Ciscar, Eva M Trinidad, Gema Perez‐Chacon, Mansour Alsaleem, Maria Jimenez, Maria J Jimenez‐Santos, Hector Perez‐Montoyo, Adrian Sanz‐Moreno, Andrea Vethencourt, Michael Toss, Anna Petit, Maria T Soler‐Monso, Victor Lopez, Jorge Gomez‐Miragaya, Clara Gomez‐Aleza, Lacey E Dobrolecki, Michael T Lewis, Alejandra Bruna, Silvana Mouron, Miguel Quintela‐Fandino, Fatima Al‐Shahrour, Antonio Martinez‐Aranda, Angels Sierra, Andrew R Green, Emad Rakha, Eva Gonzalez‐Suarez
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 4, Pp 1-12 (2023)
Abstract Despite strong preclinical data, the therapeutic benefit of the RANKL inhibitor, denosumab, in breast cancer patients, beyond the bone, is unclear. Aiming to select patients who may benefit from denosumab, we hereby analyzed RANK and RANKL p
Externí odkaz:
https://doaj.org/article/1a7e932a6a184ce6a384d4a58e43a0be
Autor:
M. Castilla, S. Pérez, R. Guevara, J. Alemany, M. Campos, M. Pla, C. Ortega, C. Falo, A. Benítez, M. Bajen, L. Pérez, A. Valdivielso, E. Martínez, M. La Plana, H. Pérez, A. Petit, T. Soler, C. Taco, J. Ponce, A. García
Publikováno v:
Breast, Vol 68, Iss , Pp S48- (2023)
Externí odkaz:
https://doaj.org/article/c356a95e7c8c4d78b7a1e89338b1261c
Autor:
Andrea Vethencourt, Eva M Trinidad, Anna Petit, María T Soler-Monsó, Clara Gómez Aleza, Ander Urruticochea, Amparo García-Tejedor, Anna Gumà Martinez, Veronica Obadia, Silvia Vazquez, Rafael Villanueva, Adela Fernánez, Monica Cejuela, Sabela Recalde Penabad, Agostina Stradella, Miguel Gil-Gil, Sonia Pernas, Eva Gonzalez-Suarez, Catalina Falo
Publikováno v:
Cancer Research. 82:P2-08
Background: Most breast cancers (BC) exhibit low immune infiltration and are unresponsive to immunotherapy. Inhibitors of the Receptor Activator of NFkB (RANK) pathway, such as denosumab, used for the treatment of bone metastasis, have been shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::347906a2aa7c8134ef274e70efcfb32a
https://doi.org/10.1158/1538-7445.sabcs21-p2-08-10
https://doi.org/10.1158/1538-7445.sabcs21-p2-08-10
Autor:
Marina Ciscar, Eva M Trinidad, Gema Perez‐Chacon, Mansour Alsaleem, Maria Jimenez, Maria J Jimenez‐Santos, Hector Perez‐Montoyo, Adrian Sanz‐Moreno, Andrea Vethencourt, Michael Toss, Anna Petit, Maria T Soler‐Monso, Victor Lopez, Jorge Gomez‐Miragaya, Clara Gomez‐Aleza, Lacey E Dobrolecki, Michael T Lewis, Alejandra Bruna, Silvana Mouron, Miguel Quintela‐Fandino, Fatima Al‐Shahrour, Antonio Martinez‐Aranda, Angels Sierra, Andrew R Green, Emad Rakha, Eva Gonzalez‐Suarez
Publikováno v:
EMBO Molecular Medicine. 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62c108380550b08bff4430c30a01ca09
https://doi.org/10.15252/emmm.202216715
https://doi.org/10.15252/emmm.202216715
Akademický článek
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Autor:
Rajan Bhatt, Muhammad Aamir Iqbal, Alison M. Laing, A. El-Sabagh, Nizamettin Turan, Magdi T. Abdelhamid, Celaleddin Barutçular, S. Seydoşoğlu, Anowar Hossain, Fatih Cig, C. M. T. Soler, Ömer Konuşkan, Hirofumi Saneoka
Publikováno v:
March 2020. :439-446
The global population is predicted to expand to 9.1 billion by 2050. Countries around the Mediterranean Sea are predicted to achieve a combined population of 529 million by 2025. The current major challenge confronting sustainable agriculture in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cee173407f76729bd0423b1d7e4a48cf
https://doi.org/10.21475/ajcs.20.14.03.p1976
https://doi.org/10.21475/ajcs.20.14.03.p1976
Autor:
Marina Ciscar, Eva M. Trinidad, Hector Perez-Montoyo, Mansour Alsaleem, Maria J. Jimenez-Santos, Michael Toss, Adrian Sanz-Moreno, Andrea Vethencourt, Gema Perez-Chacon, Anna Petit, Maria T. Soler-Monso, Jorge Gomez-Miragaya, Clara Gomez-Aleza, Maria Jimenez, Lacey E. Dobrolecki, Michael T. Lewis, Alejandra Bruna, Silvana Mouron, Miguel Quintela-Fandino, Fatima Al-Shahrour, Antonio Martinez-Aranda, Angels Sierra, Andrew R. Green, Emad Rakha, Eva Gonzalez-Suarez
Despite strong preclinical data, the therapeutic benefit of the RANKL inhibitor denosumab in BC patients, beyond its bone-related effects, is unclear. Here, we investigated the prognostic value of RANK expression and its functionality in human BC. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6f7000e65cefd1161ec60bdb81395ea
https://doi.org/10.1101/2021.12.13.470911
https://doi.org/10.1101/2021.12.13.470911
Autor:
C. Falo Zamora, J. Azcarate, A. Petit, S. Fernandez-Gonzalez, A. Garcia-Tejedor, A. Vethencourt, S. Vazquez, H. Perez Montero, M. Laplana, E. Martinez, R. Taco, E. Guerra, M. Varela, F.J. Perez, A. Stradella, M.J. Pla, M. Gil-Gil, S. Pernas, R. Ortega, T. Soler-Monso
Publikováno v:
European Journal of Cancer. 175:S96
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f53b2074d2d97a7c154a6b1cc4519a1
https://doi.org/10.1016/s0959-8049(22)01609-4
https://doi.org/10.1016/s0959-8049(22)01609-4
Akademický článek
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Autor:
M. E. Fernandez Montoli, M. Campos Delgado, J. Ponce Sebastia, T Soler Monsó, I Morilla Ruiz, A. Garcia Tejedor, X Perez Martin, R. Ortega Martinez, A Petit Montserrar, A. Guma Martinez, M. Gil Gil, C. Falo Zamora, M-J Pla Farnós
Publikováno v:
Cancer Research. 79:P1-15
Introduction Neoadjuvant chemotherapy (NAC) in breast cancer is an in vivo marker of chemosensitivity and pathological complete response (pCR) an independent prognostic factor. When there is response, NAC downstages the tumour and may allow for or fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::867f2abf883d437b8db601f0acc8b4fe
https://doi.org/10.1158/1538-7445.sabcs18-p1-15-09
https://doi.org/10.1158/1538-7445.sabcs18-p1-15-09