Zobrazeno 1 - 10
of 1 490
pro vyhledávání: '"T, Salo"'
Autor:
Manmeet S. Dhiman, Taylor J. Bader, Dragana Ponjevic, Paul T. Salo, David A. Hart, Ganesh Swamy, John R. Matyas, Neil A. Duncan
Publikováno v:
JOR Spine, Vol 7, Iss 3, Pp n/a-n/a (2024)
Abstract Introduction Degenerative disc disease (DDD) is accompanied by structural changes in the intervertebral discs (IVD). Extra‐cellular matrix degradation of the annulus fibrosus (AF) has been linked with degeneration of the IVD. Collagen is a
Externí odkaz:
https://doaj.org/article/436a730e48364e9ca1ce1b9893c9a13f
Autor:
Viola Nähse, Camilla Raiborg, Kia Wee Tan, Sissel Mørk, Maria Lyngaas Torgersen, Eva Maria Wenzel, Mireia Nager, Veijo T. Salo, Terje Johansen, Elina Ikonen, Kay Oliver Schink, Harald Stenmark
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Cellular homeostasis is governed by removal of damaged organelles and protein aggregates by selective autophagy mediated by cargo adaptors such as p62/SQSTM1. Autophagosomes can assemble in specialized cup-shaped regions of the endoplasmic r
Externí odkaz:
https://doaj.org/article/4b4cc69eb99844d38600776ee09b1dd5
Autor:
Calvin Dumesnil, Lauri Vanharanta, Xavier Prasanna, Mohyeddine Omrane, Maxime Carpentier, Apoorva Bhapkar, Giray Enkavi, Veijo T. Salo, Ilpo Vattulainen, Elina Ikonen, Abdou Rachid Thiam
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Dumesnil et al. report that cholesterol esters (CE), which only melt above body temperature, form supercooled liquid crystalline lipid droplets (LD). Triacylglycerols (TG) solubilize CE to help CE LD nucleation. Through clustering TGs in the ER membr
Externí odkaz:
https://doaj.org/article/1cacaf49d32d4b7a9a98a9bcd3cf7d33
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract The current body of sprinting biomechanics literature together with the front-side mechanics coaching framework provide various technique recommendations for improving performance. However, few studies have attempted to systematically explor
Externí odkaz:
https://doaj.org/article/90438f6cace146c29e17fa2a50232c60
Autor:
Roman J. Krawetz, Saleem Abubacker, Catherine Leonard, Anand O. Masson, Sophia Shah, Nadia Narendran, Pankaj Tailor, Suresh C. Regmi, Elodie Labit, Nicoletta Ninkovic, Jessica May Corpuz, Kenichi Ito, T. Michael Underhill, Paul T. Salo, Tannin A. Schmidt, Jeff A. Biernaskie
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-18 (2022)
Abstract The wound healing response is one of most primitive and conserved physiological responses in the animal kingdom, as restoring tissue integrity/homeostasis can be the difference between life and death. Wound healing in mammals is mediated by
Externí odkaz:
https://doaj.org/article/6cfd5dea43f0478bbcc1d17da0a3891f
Autor:
Roman J. Krawetz, Yiru Elizabeth Wu, Karri L. Bertram, Anchita Shonak, Anand O. Masson, Guomin Ren, Catherine Leonard, Mohit Kapoor, John R. Matyas, Paul T. Salo
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-16 (2022)
Abstract Aggrecan is a critical component of the extracellular matrix of all cartilages. One of the early hallmarks of osteoarthritis (OA) is the loss of aggrecan from articular cartilage followed by degeneration of the tissue. Mesenchymal progenitor
Externí odkaz:
https://doaj.org/article/39a5e62d9d7a4f7d9e4e3ea507b01586
Autor:
Veijo T. Salo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Cells store excess energy in the form of lipid droplets (LDs), a specialized sub-compartment of the endoplasmic reticulum (ER) network. The lipodystrophy protein seipin is a key player in LD biogenesis and ER-LD contact site maintenance. Recent struc
Externí odkaz:
https://doaj.org/article/8223157f270e4134b5752d49a5698d27
Autor:
K. Juurikka, A. Dufour, K. Pehkonen, B. Mainoli, P. Campioni Rodrigues, N. Solis, T. Klein, P. Nyberg, C. M. Overall, T. Salo, P. Åström
Publikováno v:
Oncogenesis, Vol 10, Iss 5, Pp 1-14 (2021)
Abstract Matrix metalloproteinases (MMPs) modify bioactive factors via selective processing or degradation resulting in tumour-promoting or tumour-suppressive effects, such as those by MMP8 in various cancers. We mapped the substrates of MMP8 to eluc
Externí odkaz:
https://doaj.org/article/243143479b8441b3be13e8ed04f77e43
Autor:
E. L. D'Ambro, S. Schobesberger, C. J. Gaston, F. D. Lopez-Hilfiker, B. H. Lee, J. Liu, A. Zelenyuk, D. Bell, C. D. Cappa, T. Helgestad, Z. Li, A. Guenther, J. Wang, M. Wise, R. Caylor, J. D. Surratt, T. Riedel, N. Hyttinen, V.-T. Salo, G. Hasan, T. Kurtén, J. E. Shilling, J. A. Thornton
Publikováno v:
Atmospheric Chemistry and Physics, Vol 19, Pp 11253-11265 (2019)
We present measurements utilizing the Filter Inlet for Gases and Aerosols (FIGAERO) applied to chamber measurements of isoprene-derived epoxydiol (IEPOX) reactive uptake to aqueous acidic particles and associated secondary organic aerosol (SOA) forma
Externí odkaz:
https://doaj.org/article/67c691d7978f4271ac4aeb2e33456faa
Autor:
Prism S. Schneider, MD, PhD, FRCSC, Herman Johal, MD, MSc, FRCSC, A. Dean Befus, PhD, Paul T. Salo, MD, FRCSC, David A. Hart, PhD, Kevin A. Hildebrand, MD, FRCSC
Publikováno v:
JBJS Open Access, Vol 6, Iss 1 (2021)
Background:. Posttraumatic joint contracture is a debilitating complication following an acute fracture or intra-articular injury that can lead to loss of motion and an inability to complete activities of daily living. In prior studies using an estab
Externí odkaz:
https://doaj.org/article/b882bd4c03084b89beda63bb7ba9452c