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Akademický článek
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Publikováno v:
Nuklearmedizin. 42:15-18
Summary Aim: The sodium/iodide symporter (NIS) actively transports iodide into thyrocytes. Thus, NIS represents a key protein for diagnosis and radioiodine therapy of differentiated thyroid cancer. Additionally, in the future the NIS gene may be used
Autor:
Wolfram H. Knapp, Matthias Weckesser, A. R. Boerner, D. Otto, H Fricke, Michael Hofmann, T. Petrich, E. Weckesser, Karl-Josef Langen
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 29:231-236
Treatment with isotretinoin (13-cis-retinoic acid, 13-cis-RA) is a recent additional option in advanced, otherwise intractable differentiated thyroid cancers. The aim of this study was to evaluate fluorine-18 fluorodeoxyglucose positron emission tomo
Autor:
A. Widjaja, D. Otto, B. Soudah, Börner Ar, M. Hofmann, E. Weckesser, T. Petrich, Hans Kreipe, Wolfram H. Knapp
Publikováno v:
Nuklearmedizin. 40:7-14
Summary Aim: In the follow-up of patients with advanced stage thyroid cancer radioiodine scintigraphy, F-l 8-FDG PET and tumormarker hTg using stimulation with recombinant human TSH (rhTSH) were compared to the results of same diagnostic procedures d
Autor:
T Petrich, R Lichtinghagen, M Wehmeier, E Hesse, E. Pötter, R von Wasielewski, Petra B. Musholt, Thomas J. Musholt
Publikováno v:
British Journal of Cancer
Supposedly, thyrocyte-specific transcripts such as thyroglobulin (Tg) and thyroid-stimulating hormone receptor (TSH-R) were proposed to be useful for the diagnosis of circulating tumour cells in patients suffering from differentiated thyroid carcinom
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 113
Publikováno v:
European journal of nuclear medicine and molecular imaging. 32(7)
Publikováno v:
Nuklearmedizin. Nuclear medicine. 42(1)
The sodium/iodide symporter (NIS) actively transports iodide into thyrocytes. Thus, NIS represents a key protein for diagnosis and radioiodine therapy of differentiated thyroid cancer. Additionally, in the future the NIS gene may be used for cancer g
Publikováno v:
European journal of nuclear medicine and molecular imaging. 29(7)
The sodium/iodide symporter (NIS) has been recognized as an attractive target for radioiodine-mediated cancer gene therapy. In this study we investigated the role of human NIS for cellular uptake of the high LET alpha-emitter astatine-211 ((211)At) i