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Akademický článek

Deep through-flow in the Bight Fracture Zone

Publikováno v: Ocean Science, Vol 18, Pp 1055-1071 (2022)

Iceland–Scotland Overflow Water (ISOW) is exported from the Nordic Seas into the Iceland Basin to feed the lower limb of the Meridional Overturning Circulation. The Bight Fracture Zone (BFZ) is known to be a major route for ISOW toward the Irminger

Externí odkaz: https://doaj.org/article/1d0a8f4db8f74d5bb92b293846b36da0

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Akademický článek

Inherent optical properties of dissolved and particulate matter in an Arctic fjord (Storfjorden, Svalbard) in early summer

Autor: T. Petit, B. Hamre, H. Sandven, R. Röttgers, P. Kowalczuk, M. Zablocka, M. A. Granskog

Publikováno v: Ocean Science, Vol 18, Pp 455-468 (2022)

There have been considerable efforts to understand the hydrography of Storfjorden (Svalbard). A recurring winter polynya with large sea ice production makes it an important region of dense water formation at the scale of the Arctic Ocean. In addition

Externí odkaz: https://doaj.org/article/e24ba443dc7c4697b481a0ecf213e34a

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Akademický článek

Capecitabine efficacy after cycline-dependent-kinase 4/6 inhibitor plus endocrine therapy in metastatic hormone receptor-positive breast cancer

Autor: L. Bender, C. Pflumio, P. Trensz, L. Pierard, M. Kalish, C. Fischbach, T. Petit

Publikováno v: Cancer Treatment and Research Communications, Vol 36, Iss , Pp 100738- (2023)

Background: The combination of endocrine treatment with cycline-dependent-kinase 4/6 inhibitor is the new standard of treatment in hormone receptor-positive HER2 negative metastatic breast cancer. The optimal subsequent treatment after CDK4/6 inhibit

Externí odkaz: https://doaj.org/article/0e75e1f89e294e669525927775aba771

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Akademický článek

Role of air–sea fluxes and ocean surface density in the production of deep waters in the eastern subpolar gyre of the North Atlantic

Autor: T. Petit, M. S. Lozier, S. A. Josey, S. A. Cunningham

Publikováno v: Ocean Science, Vol 17, Pp 1353-1365 (2021)

Wintertime convection in the North Atlantic Ocean is a key component of the global climate as it produces dense waters at high latitudes that flow equatorward as part of the Atlantic Meridional Overturning Circulation (AMOC). Recent work has highligh

Externí odkaz: https://doaj.org/article/c912679a9fc24067913b4b9d25d75958

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Akademický článek

Subpolar North Atlantic western boundary density anomalies and the Meridional Overturning Circulation

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)

Western boundary current variability in the subpolar North Atlantic is thought to reflect interior convection changes and determine Atlantic Meridional Overturning Circulation variability. Here, the authors show with an extended OSNAP time series tha

Externí odkaz: https://doaj.org/article/ba890071bef94ff6953f89928e5903d9

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Akademický článek

Randomised, open-label, multicentric phase III trial to evaluate the safety and efficacy of palbociclib in combination with endocrine therapy, guided by ESR1 mutation monitoring in oestrogen receptor-positive, HER2-negative metastatic breast cancer patients: study design of PADA-1

Autor: C Cheneau, S Barthier, J Lemonnier, Fabrice Andre, C Dubot, L Teixeira, A Escande, T De La Motte Rouge, T Petit, L Arnould, Laurent Arnould, Suzette Delaloge, Jerome Lemonnier, A Marti, L Stefani, F Berger, C Levy, P Barthelemy, S Nguyen, M Gardner, A Lortholary, François-Clément Bidard, J Plaza, L Joly, Thibault de la Motte Rouge, F Andre, I Bièche, C Alleaume, R Sabatier, B Lucas, Ivan Bieche, O Derbel, L Venat-Bouvet, F Del Piano, Florian Clatot, Anne-Claire Hardy-Bessard, Frédérique Berger, Margaux Marce, Thomas Bachelot, Anne Pradines, Jean-Luc Canon, Sandrine Marques, M Achille, H Ammarguellat, O Arsene, T Bachelot, C Bernard-Marty, F-C Bidard, N Bonichon-Lamichhane, N Bonnin, R Bouaita, A Boudrant, V-A Brunel, C Chakiba, F Clatot, F Dalenc, A De Gramont, L Deiana, C Delbaldo, V Delecroix, H Desclos, V D'Hondt, N Dohollou, J-M Ferrero, C Foa, J-S Frenel, C Garnier Tixidre, D Genet, O Gisserot, M Gozy, C Greilsamer, J Grenier, F Guinet, A-C Hardy-Bessard, J-P Jacquin, E Lachaier, S Ladoire, A-P Laurenty, R Le Scodan, N Leduc, E Legouffe, C Levache, F Lorchel, N Marques, J Medioni, A Melis, D Mille, D Mollon, L Moreau, I Moullet, M-A Mouret-Reynier, A Najem, H Orfeuvre, J-F Paitel, B Pistilli, C Riedl, P Soulie, D Spaeth, F Trouboul, C Valmar, H Vegas, A Zannetti, FC Bidard, S Delaloge, A Pradines, JL Canon, S Marques

Publikováno v: BMJ Open, Vol 12, Iss 3 (2022)

Introduction The combination of a CDK4/6 inhibitor with an aromatase inhibitor (AI) has recently become the gold standard for AI-sensitive first line treatment of oestrogen receptor-positive (ER+) HER2-negative (HER2−) advanced breast cancer. Howev

Externí odkaz: https://doaj.org/article/8faf6bbc845f4ceeb90674dd08e198da

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