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Deviated overexpression of TCR-beta, TCR-gamma, CD4, and CD8 on thymic lymphomas induced by 1-propyl-1-nitrosourea: destruction of the allelic exclusion of TCR-beta and expression of functional TCR-betagamma heterodimer on a lymphoma, cFTL53

Autor: M Kinebuchi, A Matsuura, T Ogiu, K Kikuchi

Publikováno v: The Journal of Immunology. 159:748-756

Thymic lymphomas (FTLs) induced by the chemical carcinogen 1-propyl-1-nitrosourea (PNU) in F344 rats showed deviated overexpression of TCR-beta, TCR-gamma, CD4, and CD8. Even though most FTLs were in the CD4+ CD8+ stage, all FTLs expressed TCR-beta m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d552d2b58e6985ca0b3fc3e65bdcc37
https://doi.org/10.4049/jimmunol.159.2.748

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Comparison of dose-dependent enhancing effects of ?-ray irradiation on urethan-induced lung tumorigenesis in athymic nude (nu/nu) mice and euthymic (nu/+) littermates

Autor: Sadayoshi Kobayashi, H Otsu, Y Noda, T Ogiu

Publikováno v: Journal of Cancer Research and Clinical Oncology. 122:231-236

The role of immunological surveillance in carcinogenesis is still controversial. In our previous experiments, urethan-induced lung tumorigenesis in athymic (nu/nu) mice and euthymic (nu/+) littermates was examined, and it was concluded that immunosur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21775c0dac3f32a33b6936aabcb7383f
https://doi.org/10.1007/bf01209651

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Induction of ovarian tumors by heavy ion irradiation in B6C3F1 mice

Autor: Nariaki Fujimoto, M Nishizaki, Hiromitsu Watanabe, Shuneki Shoji, Ken Kuramoto, Osamu Katoh, S Kido, Y Ishimura, T Ogiu, Shitau Hirata, K Shiraki

Publikováno v: Oncology reports. 5(6)

Six-week-old B6C3F1 mice were exposed to 0.439 Gy heavy ion irradiation as a 290 MeV/u carbon-ion beam (LET 10 keV/micron) at 2 cm from the upper proximal point of a spread Bragg beam and autopsied 13.5 months after the irradiation. In males total tu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3de351cb62accf322e9e6599edd328
https://pubmed.ncbi.nlm.nih.gov/9769371

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Comparison of dose-dependent enhancing effects of gamma-ray irradiation on urethan-induced lung tumorigenesis in athymic nude (nu/nu) mice ac (nu/+) littermates

Autor: S, Kobayashi, H, Otsu, Y, Noda, T, Ogiu

Publikováno v: Journal of cancer research and clinical oncology. 122(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::36bce5347082fb3f7d9b95a7538ad1ad
https://pubmed.ncbi.nlm.nih.gov/8601576

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Reduced fidelity of DNA synthesis in cell extracts from chemically induced primary thymic lymphomas of mice

Autor: Y, Kubota, K, Murakami-Murofushi, Y, Shimada, T, Ogiu, T, Oikawa

Publikováno v: Cancer research. 55(17)

To examine whether the fidelity of DNA synthesis is reduced in tumor cells, M13 mp2-based fidelity assays were carried out using 15 samples of whole-cell extracts from primary mouse thymic lymphomas induced by alkylating agents. We found that DNA syn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9465250e7f3318f91736550793368b84
https://pubmed.ncbi.nlm.nih.gov/7641192

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Age-dependent induction of thymic lymphomas by N-propyl-N-nitrosourea in the F344/DuCrj rat

Autor: T, Ogiu, H, Fukami, M, Nishimura, Y, Shimada, A, Maekawa

Publikováno v: Thymus. 20(4)

N-Propyl-N-nitrosourea (PNU) is one of the most potent thymic-lymphomagenic agents in rats. Our previous experiments strongly suggested that leukemogenic viruses were not the cause of thymic lymphomas in rats and that target cells of PNU exist in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::779a260974efa305725d839bb63b5480
https://pubmed.ncbi.nlm.nih.gov/1492363

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Comparative genetics of host response to N-methyl 1-N'-nitro-N-nitrosoguanidine. I. A lack of tumor production in the glandular stomach of Swiss mouse

Autor: M, Kodama, T, Kodama, H, Fukami, T, Ogiu

Publikováno v: Anticancer research. 12(2)

The present study investigated the effects of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) drink and 3 maintenance diets on both the survival and the glandular stomach morphology in a total of 480 Swiss/ICR mice. The MNNG conditioning was practised in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1ef071403a909d1f5817b65fe89bec64
https://pubmed.ncbi.nlm.nih.gov/1580561

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