P-glycoprotein efflux at the blood-brain barrier mediates differences in brain disposition and pharmacodynamics between two structurally related neurokinin-1 receptor antagonists.

Autor: J, Smith B, C, Doran A, S, McLean, D, Tingley F, T, O'Neill B, M, Kajiji S

Publikováno v: The Journal of Pharmacology and Experimental Therapeutics; September 2001, Vol. 298 Issue: 3 p1252-9, 8p