Zobrazeno 1 - 10
of 407
pro vyhledávání: '"T, Monaghan"'
Autor:
Jan Köhler, Elisabeth Varga, Stephanie Spahr, Jörn Gessner, Kerstin Stelzer, Gunnar Brandt, Miguel D. Mahecha, Guido Kraemer, Martin Pusch, Christian Wolter, Michael T. Monaghan, Matthias Stöck, Tobias Goldhammer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Climate change elevates the threat of compound heat and drought events, with their ecological and socioeconomic impacts exacerbated by human ecosystem alterations such as eutrophication, salinization, and river engineering. Here, we study ho
Externí odkaz:
https://doaj.org/article/74717ac71dfa4a3197f642c9b794df5d
Autor:
Josselin Nespoux, Marie-Louise T. Monaghan, Natalie K. Jones, Kevin Stewart, Laura Denby, Alicja Czopek, John J. Mullins, Robert I. Menzies, Andrew H. Baker, Matthew A. Bailey
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract P2X7 receptors mediate immune and endothelial cell responses to extracellular ATP. Acute pharmacological blockade increases renal blood flow and filtration rate, suggesting that receptor activation promotes tonic vasoconstriction. P2X7 expre
Externí odkaz:
https://doaj.org/article/3754b0ae722445b28dc0fc7b7de55dfa
Publikováno v:
Viruses, Vol 16, Iss 10, p 1515 (2024)
Seasonal influenza viruses continuously evolve via antigenic drift. This leads to recurring epidemics, globally significant mortality rates, and the need for annually updated vaccines. Co-occurring mutations in hemagglutinin (HA) and neuraminidase (N
Externí odkaz:
https://doaj.org/article/4d0a2c3b6d1649948c8bebfbeb6d9327
Autor:
Lucas Sire, Paul Schmidt Yáñez, Annie Bézier, Béatrice Courtial, Susan Mbedi, Sarah Sparmann, Laurent Larrieu, Rodolphe Rougerie, Christophe Bouget, Michael T. Monaghan, Elisabeth A. Herniou, Carlos Lopez-Vaamonde
Publikováno v:
PeerJ, Vol 11, p e16022 (2023)
Background Broad-scale monitoring of arthropods is often carried out with passive traps (e.g., Malaise traps) that can collect thousands of specimens per sample. The identification of individual specimens requires time and taxonomic expertise, limiti
Externí odkaz:
https://doaj.org/article/2b6097ea8f6949469c0255915fbbf26a
Autor:
Emily K. Kleczko, Dustin T. Nguyen, Kenneth H. Marsh, Colin D. Bauer, Amy S. Li, Marie-Louise T. Monaghan, Michael D. Berger, Seth B. Furgeson, Berenice Y. Gitomer, Michel B. Chonchol, Eric T. Clambey, Kurt A. Zimmerman, Raphael A. Nemenoff, Katharina Hopp
Publikováno v:
JCI Insight, Vol 8, Iss 12 (2023)
Innate and adaptive immune cells modulate the severity of autosomal dominant polycystic kidney disease (ADPKD), a common kidney disease with inadequate treatment options. ADPKD has parallels with cancer, in which immune checkpoint inhibitors have bee
Externí odkaz:
https://doaj.org/article/db0e24d1120a4e91b18a5137cdd01738
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Additive Manufacturing is transforming how researchers and industrialists look to design and manufacture chemical devices to meet their specific needs. In this work, we report the first example of a flow reactor formed via the solid-state me
Externí odkaz:
https://doaj.org/article/d0a6d031d21e4c1fafb806154208b81f
Autor:
Lucas Sire, Paul Schmidt Yáñez, Cai Wang, Annie Bézier, Béatrice Courtial, Jérémy Cours, Diego Fontaneto, Laurent Larrieu, Christophe Bouget, Simon Thorn, Jörg Müller, Douglas W. Yu, Michael T. Monaghan, Elisabeth A. Herniou, Carlos Lopez-Vaamonde
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
Sire et al. examine the effects of climate-induced forest dieback and salvage logging on insect diversity in silver fir Pyrenean forests using metabarcoding. Although no consistent variation in species richness was found, forest dieback cause massive
Externí odkaz:
https://doaj.org/article/4babeb38a64444b3a0550d5c7b840caf
Autor:
Dustin T. Nguyen, Emily K. Kleczko, Nidhi Dwivedi, Marie-Louise T. Monaghan, Berenice Y. Gitomer, Michel B. Chonchol, Eric T. Clambey, Raphael A. Nemenoff, Jelena Klawitter, Katharina Hopp
Publikováno v:
JCI Insight, Vol 8, Iss 1 (2023)
Autosomal dominant polycystic kidney disease (ADPKD), the most common monogenic nephropathy, is characterized by phenotypic variability that exceeds genic effects. Dysregulated metabolism and immune cell function are key disease modifiers. The trypto
Externí odkaz:
https://doaj.org/article/309833323f31402ebb2adcd39a55bdfc
Publikováno v:
Mitochondrial DNA. Part B. Resources, Vol 6, Iss 10, Pp 2969-2971 (2021)
Mayflies (Ephemeroptera) are a semi-aquatic insect order with comparatively few genomic data available despite their phylogenetic position at the root of the winged-insects and possession of ancestral traits. Here, we provide three mitochondrial geno
Externí odkaz:
https://doaj.org/article/ab966d4b2bb94ad58a852a1de338fd34
Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors
Autor:
Jue Xiang Wang, Mark W. Irvine, Erica S. Burnell, Kiran Sapkota, Robert J. Thatcher, Minjun Li, Noriko Simorowski, Arturas Volianskis, Graham L. Collingridge, Daniel T. Monaghan, David E. Jane, Hiro Furukawa
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Selectively inhibiting N-Methyl-D-aspartate receptors (NMDARs) containing the GluN2C/2D subunits has been challenging. Here, using electrophysiology and X-ray crystallography, authors show that compounds UBP791 and UBP1700 show over 40- and 50-fold s
Externí odkaz:
https://doaj.org/article/9cf4ff26eb1b4740b5b19c5f54918691