Zobrazeno 1 - 10
of 277
pro vyhledávání: '"T, Merrick"'
Publikováno v:
BMJ Open, Vol 13, Iss 10 (2023)
Introduction Child sexual abuse (CSA) poses a significant threat to the health and well-being of children in the USA and globally. Many states have introduced or implemented policies to address and prevent CSA, but little research has linked the effe
Externí odkaz:
https://doaj.org/article/12174b2262da47fb8d8bddd0f702bff1
Autor:
Emily K. Kleczko, Trista K. Hinz, Teresa T. Nguyen, Natalia J. Gurule, Andre Navarro, Anh T. Le, Amber M. Johnson, Jeff Kwak, Diana I. Polhac, Eric T. Clambey, Mary Weiser-Evans, Daniel T. Merrick, Michael C. Yang, Tejas Patil, Erin L. Schenk, Lynn E. Heasley, Raphael A. Nemenoff
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-11 (2023)
Abstract Lung cancers bearing oncogenic EML4-ALK fusions respond to targeted tyrosine kinase inhibitors (TKIs; e.g., alectinib), with variation in the degree of shrinkage and duration of treatment (DOT). However, factors that control this response ar
Externí odkaz:
https://doaj.org/article/8192c462eff74d50be9a1f7314bb046e
Autor:
York E. Miller, Moumita Ghosh, Daniel T. Merrick, Brandi Kubala, Eva Szabo, Lisa Bengtson, Masha Kocherginsky, Irene B. Helenowski, Kelly Benante, Tia Schering, Jihye Kim, Hyunmin Kim, Duc Ha, Raymond C. Bergan, Seema A. Khan, Robert L. Keith
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionIloprost, a prostacyclin analog, has lung cancerpreventive activity in preclinical models and improved dysplasia in former smokers in a phase IIb trial. Oral iloprost is currently unavailable. We performed a phase Ib trial of inhaled ilop
Externí odkaz:
https://doaj.org/article/502903e34d9c4e43b8cf25ff8ca2f407
Autor:
T. Merrick, S. Pau, M. Detto, E. N. Broadbent, S. A. Bohlman, C. J. Still, A. M. Almeyda Zambrano
Publikováno v:
Biogeosciences, Vol 18, Pp 6077-6091 (2021)
Recently, remotely sensed measurements of the near-infrared reflectance (NIRv) of vegetation, the fluorescence correction vegetation index (FCVI), and radiance (NIRvrad) of vegetation have emerged as indicators of vegetation structure and function wi
Externí odkaz:
https://doaj.org/article/5bf07e4cca8c496d9e0a7c652712c525
Autor:
Natalia J. Gurule, Caroline E. McCoach, Trista K. Hinz, Daniel T. Merrick, Adriaan Van Bokhoven, Jihye Kim, Tejas Patil, Jacob Calhoun, Raphael A. Nemenoff, Aik Choon Tan, Robert C. Doebele, Lynn E. Heasley
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-11 (2021)
Abstract Tyrosine kinase inhibitors (TKIs) targeting EGFR-mutant lung cancers promote a range of tumor regression responses to yield variable residual disease, a likely incubator for acquired resistance. Herein, rapid transcriptional responses induce
Externí odkaz:
https://doaj.org/article/d5ae4b79688c4b8094ee97ddf345427d
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-5 (2020)
Abstract Background Dabrafenib and trametinib combination therapy is approved for the treatment of patients with BRAF V600E positive tumors including melanoma and lung cancer. The effect of BRAF and MEK inhibitors on the immune system is not fully un
Externí odkaz:
https://doaj.org/article/01f0b501c2d848568da252462225f0fb
Autor:
J. Bart Klika, Kathryn Maguire-Jack, Megan Feely, William Schneider, Garrett T. Pace, Whitney Rostad, Catherine A. Murphy, Melissa T. Merrick
Publikováno v:
Children, Vol 10, Iss 1, p 64 (2022)
In the United States, childcare subsidies are available to low-income working parents to assist with the cost of childcare. The subsidies are provided as block grants to states, which allows for a great deal of flexibility in the specific policies gu
Externí odkaz:
https://doaj.org/article/151e9f98ef9d4536adc30dbed89cfd1d
Autor:
Lori D. Dwyer‐Nield, Debbie G. McArthur, Tyler M. Hudish, Laura I. Hudish, Carol Mirita, Kayla Sompel, Alex J. Smith, Kiana Alavi, Moumita Ghosh, Daniel T. Merrick, Meredith A. Tennis, Robert L. Keith
Publikováno v:
International Journal of Cancer. 151:2195-2205
The N-nitroso-trischloroethylurea (NTCU)-induced mouse model of squamous lung carcinoma recapitulates human disease from premalignant dysplasia through invasive tumors, making it suitable for preclinical chemoprevention drug testing. Pioglitazone is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a8cce7f7c1e830b58a049e7bf087ed6
https://doi.org/10.1002/ijc.34210
https://doi.org/10.1002/ijc.34210
Publikováno v:
Seminars in Oncology. 49:254-260
Lung cancer (both adenocarcinoma and squamous cell) progress through a series of pre-malignant histologic changes before the development of invasive disease. Each of these carcinogenic cascades is defined by genetic and epigenetic alterations in pulm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50da7dc5bb5e5522f739030b4e5f0f4
https://doi.org/10.1053/j.seminoncol.2022.02.001
https://doi.org/10.1053/j.seminoncol.2022.02.001
Autor:
York E. Miller, Mark W. Geraci, Mary K. Jackson, Lori D. Dwyer-Nield, Brandi Bagwell, Paul A. Bunn, Daniel T. Merrick, Patrick J. Blatchford, Robert L. Keith
Lung cancer chemoprevention, especially in high-risk former smokers, has great potential to reduce lung cancer incidence and mortality. Thiazolidinediones prevent lung cancer in preclinical studies, and diabetics receiving thiazolidinediones have low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24284c87b064233f958cb6b8c03e01c9
https://doi.org/10.1158/1940-6207.c.6546992.v1
https://doi.org/10.1158/1940-6207.c.6546992.v1
