Zobrazeno 1 - 10
of 178
pro vyhledávání: '"T, McMillen"'
Autor:
Sheng-Bin Peng, Sajan Joseph, Ramon V. Tiu, Gregory D. Plowman, Michael J. Rodriguez, Eunice Yuen, Jennie Walgren, Jason Manro, Andrew J. Dropsey, Denis McCann, Xi Rao, Robert D. Van Horn, Meghann Pogue, Xiu-Juan Yuan, Yan Zhai, Bryan Anderson, Wenjuan Wu, Robert S. Flack, Lisa Kindler, Weihua Shen, Matthew Whitesell, Baohui Zhao, Shufen Cai, William T. McMillen, Shripad V. Bhagwat
The ERK pathway is critical in oncogenesis; aberrations in components of this pathway are common in approximately 30% of human cancers. ERK1/2 (ERK) regulates cell proliferation, differentiation, and survival and is the terminal node of the pathway.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b6b83642603b80faa51fcf05c737a2b
https://doi.org/10.1158/1535-7163.c.6538636.v1
https://doi.org/10.1158/1535-7163.c.6538636.v1
Autor:
Sheng-Bin Peng, Sajan Joseph, Ramon V. Tiu, Gregory D. Plowman, Michael J. Rodriguez, Eunice Yuen, Jennie Walgren, Jason Manro, Andrew J. Dropsey, Denis McCann, Xi Rao, Robert D. Van Horn, Meghann Pogue, Xiu-Juan Yuan, Yan Zhai, Bryan Anderson, Wenjuan Wu, Robert S. Flack, Lisa Kindler, Weihua Shen, Matthew Whitesell, Baohui Zhao, Shufen Cai, William T. McMillen, Shripad V. Bhagwat
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d0dc26b8998855020bf945222d1189
https://doi.org/10.1158/1535-7163.22507273.v1
https://doi.org/10.1158/1535-7163.22507273.v1
Autor:
Sheng-Bin Peng, Sajan Joseph, Ramon V. Tiu, Gregory D. Plowman, Michael J. Rodriguez, Eunice Yuen, Jennie Walgren, Jason Manro, Andrew J. Dropsey, Denis McCann, Xi Rao, Robert D. Van Horn, Meghann Pogue, Xiu-Juan Yuan, Yan Zhai, Bryan Anderson, Wenjuan Wu, Robert S. Flack, Lisa Kindler, Weihua Shen, Matthew Whitesell, Baohui Zhao, Shufen Cai, William T. McMillen, Shripad V. Bhagwat
In vivo effect of treatment on body weight loss.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952c561d8520c3c104049374b206e09a
https://doi.org/10.1158/1535-7163.22507276.v1
https://doi.org/10.1158/1535-7163.22507276.v1
Autor:
Sheng-Bin Peng, Sajan Joseph, Ramon V. Tiu, Gregory D. Plowman, Michael J. Rodriguez, Eunice Yuen, Jennie Walgren, Jason Manro, Andrew J. Dropsey, Denis McCann, Xi Rao, Robert D. Van Horn, Meghann Pogue, Xiu-Juan Yuan, Yan Zhai, Bryan Anderson, Wenjuan Wu, Robert S. Flack, Lisa Kindler, Weihua Shen, Matthew Whitesell, Baohui Zhao, Shufen Cai, William T. McMillen, Shripad V. Bhagwat
Summary of antitumor activity of LY3214996 and other MAPK pathway inhibitors in cancer models with dominant MAPK pathway alterations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6c4588b08e0998a9a4807fcc3a711c
https://doi.org/10.1158/1535-7163.22507261.v1
https://doi.org/10.1158/1535-7163.22507261.v1
Akademický článek
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Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Ramon V. Tiu, Michael John Rodriguez, Meghann Pogue, Baohui Zhao, Denis J. McCann, Xiu-Juan Yuan, Wenjuan Wu, William T. McMillen, Shufen Cai, Robert S. Flack, Gregory D. Plowman, Jason Manro, Shripad V. Bhagwat, Matthew Whitesell, Andrew J. Dropsey, Eunice Yuen, Robert D. Van Horn, Lisa Kindler, Sajan Joseph, Jennie L. Walgren, Yan Zhai, Xi Rao, Sheng-Bin Peng, Weihua Shen, Bryan D. Anderson
Publikováno v:
Molecular Cancer Therapeutics. 19:325-336
The ERK pathway is critical in oncogenesis; aberrations in components of this pathway are common in approximately 30% of human cancers. ERK1/2 (ERK) regulates cell proliferation, differentiation, and survival and is the terminal node of the pathway.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0b68b64a3ac95f9cdd0139808ce027
https://doi.org/10.1158/1535-7163.mct-19-0183
https://doi.org/10.1158/1535-7163.mct-19-0183
BackgroundVariations in regional cortical folds across individuals have been examined using computationally-derived morphological measures, or by manual characterization procedures that map distinct variants of a regional fold to a set of human-inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af54804ff7d6b6907844fbea9d529f3c
https://doi.org/10.1101/2020.11.25.388785
https://doi.org/10.1101/2020.11.25.388785
Publikováno v:
PLoS Computational Biology, Vol 4, Iss 8, p e1000157 (2008)
Locomotion provides superb examples of cooperation among neuromuscular systems, environmental reaction forces, and sensory feedback. As part of a program to understand the neuromechanics of locomotion, here we construct a model of anguilliform (eel-l
Externí odkaz:
https://doaj.org/article/ca3c52a9926a4becbab33417782fb8ed
Autor:
Michael Lahn, Faming Zhang, William T. McMillen, Jeremy R. Graff, Rikke B. Holmgaard, Chandrasekar V. Iyer, Jason Manro, Bryan D. Anderson, Douglas W. Beight, Maria Jose Lallena, Kyla Driscoll, Lei Yan, J. Scott Sawyer, Michael Kalos, Karen S. Britt, David K. Clawson, Philip W. Iversen, Rolf A. Brekken, Karim A. Benhadji, Xiaohong Xu, Durisala Desaiah, Jonathan Michael Yingling, Huocong Huang
Publikováno v:
Oncotarget
Transforming growth factor-β (TGFβ) is an important driver of tumor growth via intrinsic and extrinsic mechanisms, and is therefore an attractive target for developing cancer therapeutics. Using preclinical models, we characterized the anti-tumor a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d8441d71dc2f3af0b1cfba12364fde
https://doi.org/10.18632/oncotarget.23795
https://doi.org/10.18632/oncotarget.23795