Zobrazeno 1 - 10
of 505
pro vyhledávání: '"T, McLean"'
Autor:
Dalton T. McLean, Jennifer J. Meudt, Loren D. Lopez Rivera, Dominic T. Schomberg, Derek M. Pavelec, Tyler T. Duellman, Darya G. Buehler, Patrick B. Schwartz, Melissa Graham, Laura M. Lee, Keri D. Graff, Jamie L. Reichert, Sandra S. Bon-Durant, Charles M. Konsitzke, Sean M. Ronnekleiv-Kelly, Dhanansayan Shanmuganayagam, C. Dustin Rubinstein
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Neurofibromatosis Type 1 (NF1) is one of the most common genetically inherited disorders that affects 1 in 3000 children annually. Clinical manifestations vary widely but nearly always include the development of cutaneous, plexiform and diffuse neuro
Externí odkaz:
https://doaj.org/article/0f275dea337648fba3fdc744507e7930
Autor:
Brian R. Silliman, Christine Angelini, Gesche Krause, Megan I. Saunders, Carter S. Smith, Stephanie R. Valdez, Josette E. T. McLean, Avery B. Paxton, Tjisse van der Heide, Avigdor Abelson
Publikováno v:
Frontiers in Marine Science, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/6df6ad80cc2540a49a797a9ded7be989
Autor:
Amy L. Burns, Brad E. Sleebs, Maria Gancheva, Kimberley T. McLean, Ghizal Siddiqui, Henrietta Venter, James G. Beeson, Ryan O’Handley, Darren J. Creek, Shutao Ma, Sonja Frölich, Christopher D. Goodman, Geoffrey I. McFadden, Danny W. Wilson
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
IntroductionThe spread of artemisinin resistant Plasmodium falciparum parasites is of global concern and highlights the need to identify new antimalarials for future treatments. Azithromycin, a macrolide antibiotic used clinically against malaria, ki
Externí odkaz:
https://doaj.org/article/09251fb382a0406ab2e4670017894854
Autor:
Shannon C. David, Erin B. Brazel, Eve V. Singleton, Vikrant Minhas, Zoe Laan, Catherine Scougall, Austen Y. Chen, Hui Wang, Chloe J. Gates, Kimberley T. McLean, Jeremy S. Brown, Giuseppe Ercoli, Rachel A. Higgins, Paul V. Licciardi, Kim Mulholland, Justin B. Davies, Timothy R. Hirst, James C. Paton, Mohammed Alsharifi
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Streptococcus pneumoniae (Spn) remains a major cause of global mortality, with extensive antigenic diversity between capsular serotypes that poses an ongoing challenge for vaccine development. Widespread use of pneumococcal conjugate vaccine
Externí odkaz:
https://doaj.org/article/511cd819d0a5443389dd8f6cbe5374df
Autor:
Hannah N. Agnew, Erin B. Brazel, Alexandra Tikhomirova, Mark van der Linden, Kimberley T. McLean, James C. Paton, Claudia Trappetti
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Streptococcus pneumoniae is the leading cause of bacterial paediatric meningitis after the neonatal period worldwide, but the bacterial factors and pathophysiology that drive pneumococcal meningitis are not fully understood. In this work, we have ide
Externí odkaz:
https://doaj.org/article/4cc47e2da4fb452bbcb8af1819fdaad2
Autor:
Clifford Dustin Rubinstein, Dalton T. McLean, Brent P. Lehman, Jennifer J. Meudt, Dominic T. Schomberg, Kathy J. Krentz, Jamie L. Reichert, Mark B. Meyer, Marie Adams, Charles M. Konsitzke, Dhanansayan Shanmuganayagam
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Genome editing in pigs has been made efficient, practical, and economically viable by the CRISPR/Cas9 platform, representing a promising new era in translational modeling of human disease for research and preclinical development of therapies and devi
Externí odkaz:
https://doaj.org/article/c901f93349584b52870a52843c992889
Autor:
Maoge Zang, Hugo MacDermott-Opeskin, Felise G. Adams, Varsha Naidu, Jack K. Waters, Ashley B. Carey, Alex Ashenden, Kimberley T. McLean, Erin B. Brazel, Jhih-Hang Jiang, Alessandra Panizza, Claudia Trappetti, James C. Paton, Anton Y. Peleg, Ingo Köper, Ian T. Paulsen, Karl A. Hassan, Megan L. O’Mara, Bart A. Eijkelkamp
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Antimicrobial resistance is an emerging global health crisis. Consequently, we have a critical need to prolong our current arsenal of antibiotics, in addition to the development of novel treatment options.
Externí odkaz:
https://doaj.org/article/6d0881cf57d441f7bee271a358bfc5d7
Autor:
Alexandra Tikhomirova, Erin B. Brazel, Kimberley T. McLean, Hannah N. Agnew, James C. Paton, Claudia Trappetti
Publikováno v:
Pathogens, Vol 11, Iss 2, p 216 (2022)
The LuxS protein, encoded by luxS, is required for the production of autoinducer 2 (AI-2) in Streptococcus pneumoniae. The AI-2 molecule serves as a quorum sensing signal, and thus regulates cellular processes such as carbohydrate utilisation and bio
Externí odkaz:
https://doaj.org/article/f4e41ea4414940ccb18aec82d37031f1
Autor:
Christian Dietz, Curtis T. Rueden, Stefan Helfrich, Ellen T. A. Dobson, Martin Horn, Jan Eglinger, Edward L. Evans, Dalton T. McLean, Tatiana Novitskaya, William A. Ricke, Nathan M. Sherer, Andries Zijlstra, Michael R. Berthold, Kevin W. Eliceiri
Publikováno v:
Frontiers in Computer Science, Vol 2 (2020)
Open-source software tools are often used for the analysis of scientific image data due to their flexibility and transparency in dealing with rapidly evolving imaging technologies. The complex nature of image analysis problems frequently requires man
Externí odkaz:
https://doaj.org/article/91391eeb82f04522acacec4a4a66efbc
Publikováno v:
Earthquake Engineering & Structural Dynamics. 51:1522-1539
This paper is motivated by the renewed interest in space exploration and the need to provide structurally sound and resource-efficient shielding solutions for valuable assets and future habitable modules. We present, implement and test a methodology