Zobrazeno 1 - 10
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pro vyhledávání: '"T, Mazzone"'
Akademický článek
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Akademický článek
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Publikováno v:
Journal of Lipid Research, Vol 38, Iss 5, Pp 981-991 (1997)
Previous studies have demonstrated that atherosclerotic lesions contain apoE synthesized primarily by macrophages. As oxidized LDL has been implicated in the development of atherosclerosis, its effect on macrophage apoE synthesis and secretion was ex
Externí odkaz:
https://doaj.org/article/329176f3a66a40c886af020a7e4b0637
Cholesterol homeostasis is modulated by amphiphiles at transcriptional and post-transcriptional loci
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 3, Pp 534-539 (1996)
A variety of amphiphiles inhibit plasma membrane cholesterol esterification and induce 3-hydroxy-3-methylglutaryl-coenzyme A reductase accumulation in cultured cells; among these are steroids, hydrophobic amines, phenothiazines, ionophores, colchicin
Externí odkaz:
https://doaj.org/article/3a3df29e6195421f8a85ab0f7f450dfb
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 3, Pp 544-551 (1995)
Macrophage foam cells must accommodate continuing fluxes of free cholesterol in spite of a greatly expanded store of cholesteryl ester. Though endogenous free cholesterol synthesis is suppressed, free cholesterol continues to enter the cell via endoc
Externí odkaz:
https://doaj.org/article/58035f1f09bb4929a880153ad69378f9
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 8, Pp 1345-1353 (1994)
Expression of apolipoprotein (apo) E by macrophages is tightly regulated by cellular cholesterol content. We have investigated a potential modulating role for apoE on macrophage cholesterol homeostasis by stably transfecting the J774 macrophage, whic
Externí odkaz:
https://doaj.org/article/a2c35817ddad4cc5b696a17c6895b00b
Autor:
T Mazzone, K Basheeruddin
Publikováno v:
Journal of Lipid Research, Vol 32, Iss 3, Pp 507-514 (1991)
The control of apoE gene expression by sterols and the relationship between regulation of the apoE and low density lipoprotein (LDL) receptor genes were investigated in a human macrophage line. Incubation of THP1 cells in either LDL or acetylated LDL
Externí odkaz:
https://doaj.org/article/88e776c595334e60ab2d631e9ef8d779
Akademický článek
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Publikováno v:
Journal of Lipid Research, Vol 30, Iss 7, Pp 1055-1064 (1989)
The relationship between macrophage cholesterol content and apolipoprotein E (apoE) gene expression was investigated in cultured mouse peritoneal macrophages. Acetylated low density lipoprotein (ALDL) at 25 micrograms/ml led to increased macrophage m
Externí odkaz:
https://doaj.org/article/7e089feadc5f49419a454902f5013948
Publikováno v:
Journal of Lipid Research, Vol 29, Iss 2, Pp 191-201 (1988)
The livers of both baboons and rhesus monkeys fed a high fat, high cholesterol diet secreted very low density lipoproteins (VLDL) that were enriched in cholesteryl ester and apoe as compared to VLDL secreted by the livers of chow-fed animals. Stimula
Externí odkaz:
https://doaj.org/article/58089a1fc25d48699d53b699b6ed8d0e