Zobrazeno 1 - 10
of 898
pro vyhledávání: '"T, Maloney"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract English speakers use probabilistic phrases such as likely to communicate information about the probability or likelihood of events. Communication is successful to the extent that the listener grasps what the speaker means to convey and, if c
Externí odkaz:
https://doaj.org/article/b2de96ef1af24af2ba9bbd72febca846
Autor:
Keiji Ota, Laurence T Maloney
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 5, p e1011999 (2024)
Bayesian decision theory (BDT) is frequently used to model normative performance in perceptual, motor, and cognitive decision tasks where the possible outcomes of actions are associated with rewards or penalties. The resulting normative models specif
Externí odkaz:
https://doaj.org/article/b2cc3a1b701a4d239c5d2b1fd90fe959
Autor:
Lauren T. Maloney, Emile Latour, Yiyi Chen, Douglas Rice, Alison Grossblatt-Wait, Nima Nabavizadeh, Charles R. Thomas, Kristina H. Young, Joshua M. Walker, John Holland, Aaron J. Grossberg
Publikováno v:
Cancer Biology & Therapy, Vol 23, Iss 1, Pp 1-8 (2022)
Stereotactic body radiotherapy (SBRT) demonstrates excellent local control in early stage lung cancer, however a quarter of patients develop recurrence or distant metastasis. Transforming growth factor-beta (TGF-β) supports metastasis and treatment
Externí odkaz:
https://doaj.org/article/7f9dfe151dab42c3b57610aef880d88e
Autor:
Xiang Wang, Vitaliy V Bondar, Oliver B Davis, Michael T Maloney, Maayan Agam, Marcus Y Chin, Audrey Cheuk-Nga Ho, Rajarshi Ghosh, Dara E Leto, David Joy, Meredith EK Calvert, Joseph W Lewcock, Gilbert Di Paolo, Robert G Thorne, Zachary K Sweeney, Anastasia G Henry
Publikováno v:
eLife, Vol 12 (2023)
Leucine-rich repeat kinase 2 (LRRK2) variants associated with Parkinson’s disease (PD) and Crohn’s disease lead to increased phosphorylation of its Rab substrates. While it has been recently shown that perturbations in cellular homeostasis includ
Externí odkaz:
https://doaj.org/article/1459c4b9a28a4c35be189566695ad7a3
Publikováno v:
Australian and New Zealand Journal of Public Health, Vol 45, Iss 6, Pp 578-583 (2021)
Abstract Background: Data on previous alcohol use in surgical patients who died in the Northern Territory (NT) are lacking and have important public health implications. Methods: The prevalence of previous alcohol (ab)use among surgical patients who
Externí odkaz:
https://doaj.org/article/b73a9777df90466fa23bc055c8018dbb
Autor:
Xiang Wang, Elvira Negrou, Michael T. Maloney, Vitaliy V. Bondar, Shan V. Andrews, Manuel Montalban, Ceyda Llapashtica, Romeo Maciuca, Hoang Nguyen, Hilda Solanoy, Annie Arguello, Laralynne Przybyla, Nathan J. Moerke, Sarah Huntwork-Rodriguez, Anastasia G. Henry
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Variants in the leucine-rich repeat kinase 2 (LRRK2) gene are associated with increased risk for familial and sporadic Parkinson’s disease (PD). Pathogenic variants in LRRK2, including the common variant G2019S, result in increased LRRK2 k
Externí odkaz:
https://doaj.org/article/1aca3cf646994a96a51018658104a0b3
Autor:
Ryan T. Maloney
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Within populations, individuals show a variety of behavioral preferences, even in the absence of genetic or environmental variability. Neuromodulators affect these idiosyncratic preferences in a wide range of systems, however, the mechanism(s) by whi
Externí odkaz:
https://doaj.org/article/477d9dea5dee44e7aa374e698d56da3d
Autor:
Michael T. Maloney, Wei Wang, Sumana Bhowmick, Ivan Millan, Mridu Kapur, Nicolas Herrera, Everett Frost, Elena Y. Zhang, Scott Song, Melissa Wang, Amelia Bora Park, Annabelle Y. Yao, Yanmin Yang
Publikováno v:
Biology, Vol 12, Iss 2, p 157 (2023)
Boosting trophic support to striatal neurons by increasing levels of brain-derived neurotrophic factor (BDNF) has been considered as a target for therapeutic intervention for several neurodegenerative diseases, including Huntington’s disease (HD).
Externí odkaz:
https://doaj.org/article/eeaee5ac5795436d956f39de5efebd64
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The brain predicts upcoming events—a fundamental operation assumed to depend on the event hazard rate and a linearly increasing uncertainty in time estimation. Here, the authors propose a simpler computation based on the reciprocal PDF, which direc
Externí odkaz:
https://doaj.org/article/ffc7d52d8e6442fe9060875005e5fc15
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Two stereoscopic cues that underlie the perception of motion-in-depth (MID) are changes in retinal disparity over time (CD) and interocular velocity differences (IOVD). These cues have independent spatiotemporal sensitivity profiles, depend upon diff
Externí odkaz:
https://doaj.org/article/68d07d8395cd453cb1e9827080136c43