Abstract 8905: Cardiac Troponin Thresholds and Kinetics to Differentiate Myocardial Injury and Myocardial Infarction

Autor: Ryan Wereski, Dorien Kimenai, Caelan Taggart, Dimitrios Doudesis, Kuan Ken Lee, Mathew T Lowry, Anda Bularga, David Lowe, Takeshi Fujisawa, Fred S Apple, Paul O Collinson, Atul Anand, Andrew Chapman, Nicholas L Mills

Publikováno v: Circulation. 144

Background: Whilst the 99th percentile is the recommended diagnostic threshold for myocardial infarction (MI), some guidelines also advocate the use of higher troponin thresholds to rule-in MI at presentation. It is unclear whether the magnitude or c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9e55bd7117cf26223f7b2c922c63a91
https://doi.org/10.1161/circ.144.suppl_1.8905

In Vivo Toxicity Assessment of Occupational Components of the Carbon Nanotube Life Cycle To Provide Context to Potential Health Effects

Autor: Lori A. Battelli, KL Bunker, Douglas E. Evans, Aleksandr B. Stefaniak, Michael L. Kashon, David T. Lowry, M. Eileen Birch, Jonathan Kang, Vamsi Kodali, Patti C. Zeidler-Erdely, Mary K. Schubauer-Berigan, Tina M. Sager, Lindsey Bishop, Marlene S. Orandle, Gary S. Casuccio, Matthew M. Dahm, Constance A. Mitchell, Jason S. Lupoi, Naveena Yanamala, Diane Schwegler-Berry, Aaron Erdely, Katelyn J. Siegrist, Aliakbar Afshari, Traci L. Lersch, Tracy Eye, Sherri Friend, Linda M. Sargent, Robert R. Mercer, Lorenzo Cena, Charles L. Geraci

Publikováno v: ACS Nano. 11:8849-8863

Pulmonary toxicity studies on carbon nanotubes focus primarily on as-produced materials and rarely are guided by a life cycle perspective or integration with exposure assessment. Understanding toxicity beyond the as-produced, or pure native material,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd22d7b8b2fab29be448470ba9a4ace9
https://doi.org/10.1021/acsnano.7b03038

Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial

Autor: Philip M Bath, Polly Scutt, Craig S Anderson, Jason P Appleton, Evind Berge, Lesley Cala, Mark Dixon, Timothy M England, Peter J Godolphin, Diane Havard, Lee Haywood, Trish Hepburn, Kailash Krishnan, Grant Mair, Alan A Montgomery, Keith Muir, Stephen J Phillips, Stuart Pocock, John Potter, Chris Price, Marc Randall, Thompson G Robinson, Christine Roffe, Peter M Rothwell, Else C Sandset, Nerses Sanossian, Jeffrey L Saver, Angela Shone, A Niroshan Siriwardena, Joanna M Wardlaw, Lisa J Woodhouse, Graham Venables, Nikola Sprigg, Pierre Amarenco, Shannon Amoils, Malcolm Jarvis, Peter Sandercock, Kjell Asplund, Colin Baigent, Sandeep Ankolekar, Harriet Howard, Christopher Lysons, Gemma Walker, Hayley Gregory, James Kirby, Jennifer Smithson, Joanne Keeling, Nadia Frowd, Robert Gray, Richard Dooley, Wim Clarke, Patricia Robinson, Zhe Kang Law, Sheila Hodgson, Adam Millington, Eleni Sakka, David Buchanan, Jeb Palmer, D Shaw, H Cobb, R Johnson, T Payne, R Spaight, A Spaight, M A Sajid, A Whileman, E Hall, H Cripps, J Toms, R Gascoyne, S Wright, M Cooper, A Palfreman, A Rajapakse, I Wynter, K Musarrat, A Mistri, C Patel, C Stephens, S Khan, S Patras, M Soliman, A Elmarimi, C Hewitt, E Watson, I Wahishi, J Hindle, L Perkin, M Wills, S Arif, S Leach, S Butler, D O'Kane, C Smith, J O'Callaghan, W Sunman, A Buck, B Jackson, C Richardson, G Wilkes, J Clarke, L Ryan, O Matias, D Mangion, A Hardwick, C Constantin, I Thomas, K Netherton, S Markova, A Hedstrom, B Rushton, C Hyde, J Scott, M Blair, M Maddula, R Donnelly, S Keane, S Johnson, H McKenzie, A Banerjee, D Hutchinson, H Goodhand, J Hill, K Mellows, M Cheeseman, V McTaggart, T Foster, L Prothero, P Saksena, A O'Kelly, H Wyllie, C Hacon, H Nutt, J North, K Goffin, J Potter, A Wiltshire, G Ravenhill, K Metcalf, L Ford, M Langley, W Davison, S Subramonian, F Magezi, I Obi, N Temple, N Butterworth-Cowin, P Oqwusu-Agyei, A F M Azim, A Nicolson, J Imam, J White, L Wood, R Fothergill, N Thompson, J Lazarus, H Werts, L Sztriha, C Ho, E McKenzie, E Owoyele, J Lim, J Aeron-Thomas, M Dockey, N Sylvester, P Rao, B M Bloom, E Erumere, G Norman, I Skene, L Cuenoud, L Howaniec, O Boulton, P Daboo, R Michael, S Al-Saadi, T Harrison, H Syed, L Argandona, S Amiani, R Perry, A Ashton, A Banaras, C Hogan, C Watchurst, E Elliott, N Francia, N Oji, R Erande, S Obarey, S Feerick, S Tshuma, E England, H Pocock, K Poole, S Manchanda, I Burn, S Dayal, K McNee, M Robinson, R Hancock, A South, C Holmes, A Steele, L B Guthrie, M Oborn, A Mohd Nor, B Hyams, C Eglinton, D Waugh, E Cann, N Wilmhurst, S Piesley, S Shave, D Dutta, M Obeid, D Ward, J Turfrey, J Glass, K Bowstead, L Hill, P Brown, S Beames, S O'Connell, V Hughes, R Whiting, J Gagg, M Hussain, M Harvey, D Karunatilake, B Pusuluri, A Witcher, C Pawley, J Allen, J Foot, J Rowe, C Lane, S Ragab, B Wadams, J Dube, B Jupp, A Ljubez, C Bagnall, G Hann, L Tucker, M Kelton, S Orr, F Harrington, A James, A Lydon, G Courtauld, K Bond, L Lucas, T Nisbett, J Kubie, A Bowring, G Jennings, K Thorpe, N Mason, S Keenan, L Gbadomishi, D Howcroft, H Newton, J Choulerton, J Avis, L Shaw, P Paterson, P Kaye, S Hierons, S Lucas, P Clatworthy, B Faulkner, L Rannigan, R Worner, B Bhaskaran, A Saulat, H Bearne, J Garfield-Smith, K Horan, P Fitzell, S Szabo, M Haley, D Simmons, D Cotterill, G Saunders, H Dymond, S Beech, K Rashed, A Tanate, C Buckley, D Wood, L Matthews, S Board, T Pitt-Kirby, N Rees, C Convery, P Jones, C Bryant, H Tench, M Dixon, R Loosley, S Coetzee, S Jones, T Sims, M Krishnan, C Davies, L Quinn, L Connor, M Wani, S Storton, S Treadwell, T Anjum, C Somashekar, A Chandler, C Triscott, L Bevan, M Sander, S Buckle, W Sayed, K Andrews, L Hughes, R Hughes, M Ward, A Pretty, A Rosser, B Davidson, G Price, I Gunson, J Lumley-Holmes, J Miller, M Larden, M Jhamat, P Horwood, R Boldy, C Jenkins, F Price, M Harrison, T Martin, N Ahmad, A Willberry, A Stevens, K Fotherby, A Barry, A Remegoso, F Alipio, H Maquire, J Hiden, K Finney, R Varquez, S Ispoglou, A Hayes, D Gull, R Evans, E Epstein, S Hurdowar, J Crossley, J Miles, K Hird, R Pilbery, C Patterson, H Ramadan, K Stewart, O Quinn, R Bellfield, S Macquire, W Gaba, A Nair, A Wilson, C Hawksworth, I Alam, J Greig, P Gomes, P Rana, Z Ahmed, P Anderston, A Neal, D Walstow, R Fong, S Brotheridge, A Bwalya, A Gillespie, C Midgley, C Hare, H Lyon, L Stephenson, M Broome, R Worton, S Jackson, R Rayessa, A Abdul-Hamid, C Naylor, E Clarkson, A Hassan, E Veraque, L Finch, L Makawa, M Carpenter, P Datta, A Needle, L Jackson, H J Brooke, J Ball, T Lowry, S Punnoose, R Walker, V Murray, A Ali, C Kamara, C Doyle, E Richards, J Howe, K Dakin, K Harkness, R Lindert, P Wanklyn, P Willcoxson, P Clark-Brown, R Mir

Publikováno v: 2019, ' Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2) : An ambulance-based, randomised, sham-controlled, blinded, phase 3 trial ', The Lancet, vol. 393, no. 10175, pp. 1009-1020 . https://doi.org/10.1016/S0140-6736(19)30194-1

Background: High blood pressure is common in acute stroke and is a predictor of poor outcome; however, large trials of lowering blood pressure have given variable results, and the management of high blood pressure in ultra-acute stroke remains unclea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe070ece802ae4e0a15375027284a78b

Cyclophosphamide-Induced Disruptions to Appetitive Qualities and Detection Thresholds of NaCl: Comparison of Single-Dose and Dose Fractionation Effects

Autor: Joy A. Benner, Eugene R. Delay, Benjamin C Jewkes, Michael G Gomella, Evan T Lowry

Publikováno v: Chemical Senses.

Chemotherapy is one of the most common treatments for cancer; however, a side effect is often altered taste. This study examined how cyclophosphamide, a chemotherapy drug, affects salt taste in mice. On the basis of previous findings, it was predicte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b722ef05d203c8e03532d22cb745cf0c
https://doi.org/10.1093/chemse/bjy026

Carbon nanotube uptake changes the biomechanical properties of human lung epithelial cells in a time-dependent manner

Autor: Linda M. Sargent, Cerasela Zoica Dinu, Michael L. Kashon, David T. Lowry, Reem Eldawud, Yon Rojanasakul, Chenbo Dong

Publikováno v: Journal of Materials Chemistry B. 3:3983-3992

The toxicity of engineered nanomaterials in biological systems depends on both the nanomaterial's properties and the exposure duration. Herein we used a multi-tier strategy to investigate the relationship between user-characterized multi-walled carbo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3b7233a21c39d7bf73fe52bd126a26
https://doi.org/10.1039/c5tb00179j