Zobrazeno 1 - 10
of 780
pro vyhledávání: '"T, Logan"'
Publikováno v:
Atmospheric Chemistry and Physics, Vol 24, Pp 10323-10347 (2024)
The aerosol–cloud–precipitation interactions within the cloud-topped marine boundary layer (MBL) are examined using aircraft in situ measurements from Aerosol and Cloud Experiments in the Eastern North Atlantic (ACE-ENA) and Southern Ocean Clouds
Externí odkaz:
https://doaj.org/article/9abcded6c91349f7bcd8bd39053a285e
Autor:
Shea L. vanden Bergh, Lakeshia T. Logan, Jonathan R. Powell, Christopher B. Gage, Kathryn R. Crawford, Lisa Collard, Michael G. Miller, Ashish R. Panchal
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 5, Iss 5, Pp n/a-n/a (2024)
Abstract Objective The COVID‐19 pandemic required unprecedented changes to emergency medical services (EMS) educational frameworks in the United States. It is unclear if pandemic‐related changes impacted paramedic educational outcomes. We aimed t
Externí odkaz:
https://doaj.org/article/6f26fcc3d24440f29c8cec1f3a77d479
Autor:
Ornella Bimai, Ipsita Banerjee, Inna Rozman Grinberg, Ping Huang, Lucas Hultgren, Simon Ekström, Daniel Lundin, Britt-Marie Sjöberg, Derek T Logan
Publikováno v:
eLife, Vol 12 (2024)
A small, nucleotide-binding domain, the ATP-cone, is found at the N-terminus of most ribonucleotide reductase (RNR) catalytic subunits. By binding adenosine triphosphate (ATP) or deoxyadenosine triphosphate (dATP) it regulates the enzyme activity of
Externí odkaz:
https://doaj.org/article/58c8ed64ca754d1ea6c8072d269703e7
Autor:
Maria Luisa Verteramo, Majda Misini Ignjatović, Rohit Kumar, Sven Wernersson, Vilhelm Ekberg, Johan Wallerstein, Göran Carlström, Veronika Chadimová, Hakon Leffler, Fredrik Zetterberg, Derek T. Logan, Ulf Ryde, Mikael Akke, Ulf J. Nilsson
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109636- (2024)
Summary: Halogen bonding is increasingly utilized in efforts to achieve high affinity and selectivity of molecules designed to bind proteins, making it paramount to understand the relationship between structure, dynamics, and thermodynamic driving fo
Externí odkaz:
https://doaj.org/article/04a7dad9b6fc435daabaaf102e239b88
Autor:
L. F. L. Wilson, T. Dendooven, S. W. Hardwick, A. Echevarría-Poza, T. Tryfona, K. B. R. M. Krogh, D. Y. Chirgadze, B. F. Luisi, D. T. Logan, K. Mani, P. Dupree
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Heparan sulphate (HS)—a common cell surface decoration—is a carbohydrate of alternating sugars assembled by bi-domain enzymes such as EXTL3. Here, authors present the structure of EXTL3, explain EXTL3 lost activity, and propose that HS extension
Externí odkaz:
https://doaj.org/article/3777beaf50494e41a670bcb58e11d529
Autor:
Inna Rozman Grinberg, Markel Martínez-Carranza, Ornella Bimai, Ghada Nouaïria, Saher Shahid, Daniel Lundin, Derek T. Logan, Britt-Marie Sjöberg, Pål Stenmark
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Ribonucleotide reductase (RNR) is an essential enzyme that catalyzes the synthesis of DNA building blocks. Here, the authors present the cryo-EM structure and mechanism of action of NrdR, the RNR-specific repressor, that controls transcription of RNR
Externí odkaz:
https://doaj.org/article/c11cf65babe14228a3e8ad1e379ec405
Autor:
Mark F. Maurer, Katherine E. Lewis, Joseph L. Kuijper, Dan Ardourel, Chelsea J. Gudgeon, Siddarth Chandrasekaran, Sherri L. Mudri, Kayla N. Kleist, Chris Navas, Martin F. Wolfson, Mark W. Rixon, Ryan Swanson, Stacey R. Dillon, Steven D. Levin, Yengo Raymond Kimbung, Masato Akutsu, Derek T. Logan, Björn Walse, Kristine M. Swiderek, Stanford L. Peng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
CD28 costimulatory signalling can be suppressed by immune checkpoints, such as CTLA-4 and PD-1. Here the authors describe the design of the fusion therapeutic davoceticept (ALPN-202), based on a variant CD80 extracellular domain engineered to bind PD
Externí odkaz:
https://doaj.org/article/1c1e0e459c4147429eef80ef95841f04
Publikováno v:
Atmospheric Chemistry and Physics, Vol 22, Pp 335-354 (2022)
Over the eastern North Atlantic (ENA) ocean, a total of 20 non-precipitating single-layer marine boundary layer (MBL) stratus and stratocumulus cloud cases are selected to investigate the impacts of the environmental variables on the aerosol–cloud
Externí odkaz:
https://doaj.org/article/a72d57c678d64b82b088da6c5532e37b
Publikováno v:
Cancer Reports, Vol 5, Iss 11, Pp n/a-n/a (2022)
Abstract Background Pleomorphic dermal sarcoma (PDS) describes rare dermal‐based malignant tumours that are morphologically similar to atypical fibroxanthoma (AFX). PDS may be differentiated from AFX by the presence of one or more of the following
Externí odkaz:
https://doaj.org/article/3d41aaf4de384cf7a26f2ced078e4125
Autor:
Johan Wallerstein, Vilhelm Ekberg, Majda Misini Ignjatović, Rohit Kumar, Octav Caldararu, Kristoffer Peterson, Sven Wernersson, Ulrika Brath, Hakon Leffler, Esko Oksanen, Derek T. Logan, Ulf J. Nilsson, Ulf Ryde, Mikael Akke
Publikováno v:
JACS Au, Vol 1, Iss 4, Pp 484-500 (2021)
Externí odkaz:
https://doaj.org/article/2981db6db17549c9b3a2c12397786a4f