Prophylactic tocilizumab reduces the incidence of cytokine release syndrome in relapsed/refractory myeloma patients treated with teclistamab: Implications for outpatient step‐up dosing

Autor: Charlotte L. B. M. Korst, Kaz Groen, Patricia W. C. Bosman, Fleur van derValk, Christie P. M. Verkleij, Sandy Kruyswijk, Maaike E. M. deRuijter, Dianne M. Heijink, Maria T. Kuipers, Sonja Zweegman, Niels W. C. J. van deDonk

Publikováno v: HemaSphere, Vol 8, Iss 7, Pp n/a-n/a (2024)

Externí odkaz: https://doaj.org/article/3a95234d406b4ae6bd0201b04fb42ff2

Optimizing Antiviral Dosing for HSV and CMV Treatment in Immunocompromised Patients

Autor: Daan W. Huntjens, Jacob A. Dijkstra, Lisanne N. Verwiel, Mirjam Slijkhuis, Paul Elbers, Matthijs R. A. Welkers, Agnes I. Veldkamp, Marianne A. Kuijvenhoven, David C. de Leeuw, Heshu Abdullah-Koolmees, Maria T. Kuipers, Imke H. Bartelink

Publikováno v: Pharmaceutics, Vol 15, Iss 1, p 163 (2023)

Herpes simplex virus (HSV) and cytomegalovirus (CMV) are DNA viruses that are common among humans. Severely immunocompromised patients are at increased risk of developing HSV or CMV disease due to a weakened immune system. Antiviral therapy can be ch

Externí odkaz: https://doaj.org/article/d1ac61ace17745d398d81e6bbaf036e9

Development of a Core Set of Patient- and Caregiver-Reported Signs and Symptoms to Facilitate Early Recognition of Acute Chimeric Antigen Receptor T-Cell Therapy Toxicities

Autor: Anne M. Spanjaart, Elise R.A. Pennings, Milan Kos, Pim G.N.J. Mutsaers, Pieternella J. Lugtenburg, Tom van Meerten, Jaap A. van Doesum, Monique C. Minnema, Margot Jak, Suzanne van Dorp, Joost S.P. Vermaat, Marjolein W.M. van der Poel, Martijn G.H. van Oijen, Maria T. Kuipers, Inger S. Nijhof, Marie José Kersten

Publikováno v: JCO Oncology Practice, 19(3), e407-e416. LIPPINCOTT WILLIAMS & WILKINS
JCO Oncology Practice, 19(3), E407-E416. American Society of Clinical Oncology
JCO oncology practice, 19(3), E407-E416. Lippincott Williams and Wilkins Ltd.
JCO oncology practice, 19(3), E407-E416. American Society of Clinical Oncology
JCO Oncology Practice, 19, 3, pp. e407-e416
JCO oncology practice, 19(3), E407-E416
American Society of Clinical Oncology
JCO Oncology Practice, 19, e407-e416
Spanjaart, A M, Pennings, E R A, Kos, M, Mutsaers, P G N J, Lugtenburg, P J, van Meerten, T, van Doesum, J A, Minnema, M C, Jak, M, van Dorp, S, Vermaat, J S P, van der Poel, M W M, van Oijen, M G H, Kuipers, M T, Nijhof, I S & Kersten, M J 2023, ' Development of a Core Set of Patient-and Caregiver-Reported Signs and Symptoms to Facilitate Early Recognition of Acute Chimeric Antigen Receptor T-Cell Therapy Toxicities ', JCO oncology practice, vol. 19, no. 3, pp. E407-E416 . https://doi.org/10.1200/OP.22.00501

PURPOSE: Prompt recognition of acute chimeric antigen receptor T (CAR T)-cell–mediated toxicities is crucial because adequate and timely management can prevent or reverse potential life-threatening complications. In the outpatient setting, patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd9ceb11818bc95c7a4f6c531735b63
https://doi.org/10.1200/OP.22.00501

The Extent of Ventilator-Induced Lung Injury in Mice Partly Depends on Duration of Mechanical Ventilation

Autor: Maria A. Hegeman, Sabrine N. T. Hemmes, Maria T. Kuipers, Lieuwe D. J. Bos, Geartsje Jongsma, Joris J. T. H. Roelofs, Koenraad F. van der Sluijs, Nicole P. Juffermans, Margreeth B. Vroom, Marcus J. Schultz

Publikováno v: Critical Care Research and Practice, Vol 2013 (2013)

Background. Mechanical ventilation (MV) has the potential to initiate ventilator-induced lung injury (VILI). The pathogenesis of VILI has been primarily studied in animal models using more or less injurious ventilator settings. However, we speculate

Externí odkaz: https://doaj.org/article/e404911d00074c35b5e2dc18ae0aeaa5

Hydrogen sulfide donor NaHS reduces organ injury in a rat model of pneumococcal pneumosepsis, associated with improved bio-energetic status.

Autor: Hamid Aslami, Wilco P Pulskens, Maria T Kuipers, Aafkeline P Bos, André B P van Kuilenburg, Ronald J A Wanders, Jeroen Roelofsen, Joris J T H Roelofs, Raphaela P Kerindongo, Charlotte J P Beurskens, Marcus J Schultz, Wim Kulik, Nina C Weber, Nicole P Juffermans

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e63497 (2013)

Sepsis is characterized by a generalized inflammatory response and organ failure, associated with mitochondrial dysfunction. Hydrogen sulfide donor NaHS has anti-inflammatory properties, is able to reduce metabolism and can preserve mitochondrial mor

Externí odkaz: https://doaj.org/article/66d0b4d10b034ee9a477c87e096ffef5