Zobrazeno 1 - 10
of 3 306
pro vyhledávání: '"T, Chao"'
Autor:
Bonnie T. Chao, Andrew T. Sage, Micheal C. McInnis, Jun Ma, Micah Grubert Van Iderstine, Xuanzi Zhou, Jerome Valero, Marcelo Cypel, Mingyao Liu, Bo Wang, Shaf Keshavjee
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-7 (2024)
Abstract Ex vivo lung perfusion (EVLP) enables advanced assessment of human lungs for transplant suitability. We developed a convolutional neural network (CNN)-based approach to analyze the largest cohort of isolated lung radiographs to date. CNNs we
Externí odkaz:
https://doaj.org/article/9b94c9591838494dbf74adbf9d2131d7
Autor:
Andrew T. Sage, Laura L. Donahoe, Alaa A. Shamandy, S. Hossein Mousavi, Bonnie T. Chao, Xuanzi Zhou, Jerome Valero, Sharaniyaa Balachandran, Aadil Ali, Tereza Martinu, George Tomlinson, Lorenzo Del Sorbo, Jonathan C. Yeung, Mingyao Liu, Marcelo Cypel, Bo Wang, Shaf Keshavjee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract Ex vivo lung perfusion (EVLP) is a data-intensive platform used for the assessment of isolated lungs outside the body for transplantation; however, the integration of artificial intelligence to rapidly interpret the large constellation of cl
Externí odkaz:
https://doaj.org/article/af760de30b88434f8af5439b2c782944
Autor:
Colton Ladbury, MD, Michael Pennock, MD, Tugba Yilmaz, MD, Nii-Kwanchie Ankrah, MBBS, Therese Andraos, MD, Emile Gogineni, DO, Grace Gwe-Ya Kim, PhD, Iris Gibbs, MD, Helen A. Shih, MD, MPH, Jona Hattangadi-Gluth, MD, Samuel T. Chao, MD, Susan C. Pannullo, MD, Ben Slotman, MD, PhD, Kristin J. Redmond, MD, MPH, Simon S. Lo, MB, ChB, Michael Schulder, MD
Publikováno v:
Advances in Radiation Oncology, Vol 9, Iss 3, Pp 101402- (2024)
Purpose: Brain metastases are common among adult patients with solid malignancies and are increasingly being treated with stereotactic radiosurgery (SRS). As more patients with brain metastases are becoming eligible for SRS, there is a need for pract
Externí odkaz:
https://doaj.org/article/8fc812aaecc3449e8048618645ebb100
Autor:
Cole Billena, Mina Lobbous, Christine A. Cordova, David Peereboom, Alejandro Torres-Trejo, Timothy Chan, Erin Murphy, Samuel T. Chao, John Suh, Jennifer S. Yu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Brain metastases are a significant source of morbidity and mortality in patients with non-small cell lung cancer. Historically, surgery and radiation therapy have been essential to maintaining disease control within the central nervous system due to
Externí odkaz:
https://doaj.org/article/58c29896976346619972a2b2dcdb3770
Autor:
Antti I. Nykänen, Andrea Mariscal, Allen Duong, Catalina Estrada, Aadil Ali, Olivia Hough, Andrew Sage, Bonnie T. Chao, Manyin Chen, Hemant Gokhale, Hongchao Shan, Xiaohui Bai, Guan Zehong, Jonathan Yeung, Tom Waddell, Tereza Martinu, Stephen Juvet, Marcelo Cypel, Mingyao Liu, John E. Davies, Shaf Keshavjee
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 184-197 (2021)
Ex vivo lung perfusion (EVLP) is an excellent platform to apply novel therapeutics, such as gene and cell therapies, before lung transplantation. We investigated the concept of human donor lung engineering during EVLP by combining gene and cell thera
Externí odkaz:
https://doaj.org/article/5f4ede1ff6fa4056972c31e49b704115
Autor:
Adam Lauko, Rupesh Kotecha, Addison Barnett, Hong Li, Vineeth Tatineni, Assad Ali, Pradnya Patil, Alireza M. Mohammadi, Samuel T. Chao, Erin S. Murphy, Lilyana Angelov, John H. Suh, Gene H. Barnett, Nathan A. Pennell, Manmeet S. Ahluwalia
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Immune checkpoint inhibitors (ICIs) have resulted in improved outcomes in non-small cell lung cancer (NSCLC) patients. However, data demonstrating the efficacy of ICIs in NSCLC brain metastases (NSCLCBM) is limited. We analyzed overall survi
Externí odkaz:
https://doaj.org/article/e1027f0afb7f466d803752a48a7d5614
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-19 (2021)
Abstract Background Genetic testing is widely used in evaluating a patient’s predisposition to hereditary diseases. In the case of cancer, when a functionally impactful mutation (i.e. genetic variant) is identified in a disease-relevant gene, the p
Externí odkaz:
https://doaj.org/article/1f0dd71d3bcf464b98546c41f890974d
Publikováno v:
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol XLIII-B2-2020, Pp 1521-1528 (2020)
Time series imagery containing high-dimensional temporal features are conducive to improving classification accuracy. With the plenty accumulation of historical images, the inclusion of time series data becomes available to utilize, but it is difficu
Externí odkaz:
https://doaj.org/article/30361f60fc404173953455c4ca8a801b
Autor:
Payel Ganguly, Landiso Madonsela, Jesse T Chao, Christopher J R Loewen, Timothy P O'Connor, Esther M Verheyen, Douglas W Allan
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009774 (2021)
Gene variant discovery is becoming routine, but it remains difficult to usefully interpret the functional consequence or disease relevance of most variants. To fill this interpretation gap, experimental assays of variant function are becoming common
Externí odkaz:
https://doaj.org/article/5cb487758be84e0eb6cf26744bfaff89
Autor:
Joseph A. Bovi, MD, Stephanie L. Pugh, PhD, David Sabsevitz, PhD, Clifford G. Robinson, MD, Eric Paulson, PhD, Minesh P. Mehta, MD, Vinai Gondi, MD, Vijayananda Kundapur, MD, Mark S. Shahin, MD, Samuel T. Chao, MD, Mitch Machtay, MD, Albert S. DeNittis, MD, Nadia N. Laack, MD, Jeffrey N. Greenspoon, MD, Kathleen N. Moore, MD, Jiayi Huang, MD, Michael M. Dominello, DO, Lisa A. Kachnic, MD
Publikováno v:
Advances in Radiation Oncology, Vol 4, Iss 4, Pp 579-586 (2019)
Purpose: NRG Oncology's RTOG 0933 demonstrated benefits to memory preservation after hippocampal avoidant whole-brain radiation therapy (HA-WBRT), the avoidance of radiation dose to the hippocampus (using intensity modulated radiation planning and de
Externí odkaz:
https://doaj.org/article/c9662f62dac04e8fb0122e9415a29190