Zobrazeno 1 - 10
of 1 176
pro vyhledávání: '"T, Byrne"'
Autor:
Tom Venken, Ian S. Miller, Ingrid Arijs, Valentina Thomas, Ana Barat, Johannes Betge, Tianzuo Zhan, Timo Gaiser, Matthias P. Ebert, Alice C. O’Farrell, Jochen Prehn, Rut Klinger, Darran P. O’Connor, Brian Moulton, Verena Murphy, Garazi Serna, Paolo G. Nuciforo, Ray McDermott, Brian Bird, Gregory Leonard, Liam Grogan, Anne Horgan, Nadine Schulte, Markus Moehler, Diether Lambrechts, Annette T. Byrne
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract To predict outcome to combination bevacizumab (BVZ) therapy, we employed cell-free DNA (cfDNA) to determine chromosomal instability (CIN), nucleosome footprints (NF) and methylation profiles in metastatic colorectal cancer (mCRC) patients. L
Externí odkaz:
https://doaj.org/article/7492becf8fc3468584cbff1ca25b4e7f
Autor:
Kathryn H. Brown, Brianna N. Kerr, Mihaela Pettigrew, Kate Connor, Ian S. Miller, Liam Shiels, Colum Connolly, Conor McGarry, Annette T. Byrne, Karl T. Butterworth
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 31, Iss , Pp 100615- (2024)
Background and purpose: Radiomics analysis extracts quantitative data (features) from medical images. These features could potentially reflect biological characteristics and act as imaging biomarkers within precision medicine. However, there is a lac
Externí odkaz:
https://doaj.org/article/2be7e99c676a450782c0e39431b9e40d
Autor:
V. Thénard, J. Quénon, G. Arsenos, G. Bailo, T.R. Baptista, T. Byrne, I. De Barbieri, G. Bruni, F. Freire, A. Theodoridis, S. Vouraki
Publikováno v:
Animal, Vol 18, Iss 7, Pp 101208- (2024)
Small ruminant farming is of socio-economic and environmental importance to many rural communities around the world. The SMARTER H2020 project aims to redefine genetic selection criteria to increase the sustainability of the sector. The objective of
Externí odkaz:
https://doaj.org/article/b27235b8331f41f7a191dbae447d1db8
Autor:
Kate Connor, Emer Conroy, Kieron White, Liam P. Shiels, Simon Keek, Abdalla Ibrahim, William M. Gallagher, Kieron J. Sweeney, James Clerkin, David O’Brien, Jane B. Cryan, Philip J. O’Halloran, Josephine Heffernan, Francesca Brett, Philippe Lambin, Henry C. Woodruff, Annette T. Byrne
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Here, we establish a CT-radiomics based method for application in invasive, orthotopic rodent brain tumour models. Twenty four NOD/SCID mice were implanted with U87R-Luc2 GBM cells and longitudinally imaged via contrast enhanced (CE-CT) imag
Externí odkaz:
https://doaj.org/article/f5502ff7e06945ad8173541c1ee43f95
Autor:
S. A. C. Richardson, D. Anderson, A. J. C. Burrell, T. Byrne, J. Coull, A. Diehl, D. Gantner, K. Hoffman, A. Hooper, S. Hopkins, J. Ihle, P. Joyce, M. Le Guen, E. Mahony, S. McGloughlin, Z. Nehme, C. P. Nickson, P. Nixon, J. Orosz, B. Riley, J. Sheldrake, D. Stub, M. Thornton, A. Udy, V. Pellegrino, S. Bernard
Publikováno v:
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 31, Iss 1, Pp 1-8 (2023)
Abstract Introduction Survival from refractory out of hospital cardiac arrest (OHCA) without timely return of spontaneous circulation (ROSC) utilising conventional advanced cardiac life support (ACLS) therapies is dismal. CHEER3 was a safety and feas
Externí odkaz:
https://doaj.org/article/5fc9cb5004ae4382ac2743ea7fffb0b3
Autor:
Burcu Gurun, Wesley Horton, Dhaarini Murugan, Biqing Zhu, Patrick Leyshock, Sushil Kumar, Katelyn T. Byrne, Robert H. Vonderheide, Adam A. Margolin, Motomi Mori, Paul T. Spellman, Lisa M. Coussens, Terence P. Speed
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract T cell receptor repertoires can be profiled using next generation sequencing (NGS) to measure and monitor adaptive dynamical changes in response to disease and other perturbations. Genomic DNA-based bulk sequencing is cost-effective but nece
Externí odkaz:
https://doaj.org/article/f072a81ae5e44edd9681ef3c1accf20e
Autor:
David T. Byrne
In this ambitious work David T. Byrne analyzes the ideas that informed Ronald Reagan's political philosophy and policies. Rather than appraising Reagan's personal and emotional life, Byrne's intellectual biography goes one step further; it establishe
Autor:
Ian S. Miller, Sonja Khan, Liam P. Shiels, Sudipto Das, Alice C. O' Farrell, Kate Connor, Adam Lafferty, Bruce Moran, Claudio Isella, Paul Loadman, Emer Conroy, Susan Cohrs, Roger Schibli, Robert S. Kerbel, William M. Gallagher, Elisabetta Marangoni, Kathleen Bennett, Darran P. O' Connor, Róisín M. Dwyer, Annette T. Byrne
Publikováno v:
Cancer Medicine, Vol 11, Iss 20, Pp 3820-3836 (2022)
Abstract Backgorund Prior data suggest pre‐diagnostic aspirin use impacts breast tumour biology and patient outcome. Here, we employed faithful surgical resection models of HER2+ and triple‐negative breast cancer (TNBC), to study outcome and resp
Externí odkaz:
https://doaj.org/article/1f5177ae512441ffab056e955c214925
Autor:
Angel M. Chater, Phoebe Brook-Rowland, Foyeke Tolani, Emily Christopher, Jo Hart, Lucie M. T. Byrne-Davis, Abby Moffat, Gillian W. Shorter, Tracy Epton, Atiya Kamal, Daryl B. O’Connor, Eleanor Whittaker, Lesley J. M. Lewis, Emily McBride, Vivien Swanson, Madelynne A. Arden
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
BackgroundThe use of behavioural science and behaviour change within local authorities and public health has supported healthful change; as evidenced by its importance and contribution to reducing harm during the COVID-19 pandemic. It can provide val
Externí odkaz:
https://doaj.org/article/8836e91ee56048828259c4015b8d71ee
Autor:
Federica Fabro, Trisha V. Kers, Kate J. Feller, Cecile Beerens, Ioannis Ntafoulis, Ahmed Idbaih, Maite Verreault, Kate Connor, Archita Biswas, Manuela Salvucci, Jochen H. M. Prehn, Annette T. Byrne, Alice C. O’Farrell, Diether Lambrechts, Gonca Dilcan, Francesca Lodi, Ingrid Arijs, Andreas Kremer, Romain Tching Chi Yen, Miao-Ping Chien, Martine L. M. Lamfers, Sieger Leenstra
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15678 (2023)
Chemotherapy using temozolomide is the standard treatment for patients with glioblastoma. Despite treatment, prognosis is still poor largely due to the emergence of temozolomide resistance. This resistance is closely linked to the widely recognized i
Externí odkaz:
https://doaj.org/article/8271d679ac384d7fb2b4f54037633904