Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy

Autor: Hector Foronda, Yangxue Fu, Adriana Covarrubias-Pinto, Hartmut T. Bocker, Alexis González, Eric Seemann, Patricia Franzka, Andrea Bock, Ramachandra M. Bhaskara, Lutz Liebmann, Marina E. Hoffmann, Istvan Katona, Nicole Koch, Joachim Weis, Ingo Kurth, Joseph G. Gleeson, Fulvio Reggiori, Gerhard Hummer, Michael M. Kessels, Britta Qualmann, Muriel Mari, Ivan Dikić, Christian A. Hübner

Publikováno v: Nature
Foronda, H, Fu, Y, Covarrubias-Pinto, A, Bocker, H T, González, A, Seemann, E, Franzka, P, Bock, A, Bhaskara, R M, Liebmann, L, Hoffmann, M E, Katona, I, Koch, N, Weis, J, Kurth, I, Gleeson, J G, Reggiori, F, Hummer, G, Kessels, M M, Qualmann, B, Mari, M, Dikić, I & Hübner, C A 2023, ' Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy ', Nature, vol. 618, no. 7964, pp. 402-410 . https://doi.org/10.1038/s41586-023-06090-9

Membrane-shaping proteins characterized by reticulon homology domains play an important part in the dynamic remodelling of the endoplasmic reticulum (ER). An example of such a protein is FAM134B, which can bind LC3 proteins and mediate the degradatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587ec4f4d78e10eb10e252a8fb732491
https://doi.org/10.1038/s41586-023-06090-9

The Na+/H+ exchanger Nhe1 modulates network excitability via GABA release

Autor: Hartmut T. Bocker, Julia Preobraschenski, Theresa Heinrich, Lutz Liebmann, Eric Seemann, Reinhard Jahn, Michael M. Kessels, J. Christopher Hennings, Melanie Gerth, Igor Jakovcevski, Christian A. Hübner, Britta Qualmann, Martin Westermann, Dirk Isbrandt

Publikováno v: Cerebral Cortex
Cerebral cortex 29(10), 4263-4276 (2018). doi:10.1093/cercor/bhy308

Brain functions are extremely sensitive to pH changes because of the pH-dependence of proteins involved in neuronal excitability and synaptic transmission. Here, we show that the Na+/H+ exchanger Nhe1, which uses the Na+ gradient to extrude H+, is ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea2b642d6617934cef548fda5e16493
https://hdl.handle.net/21.11116/0000-0004-AC16-221.11116/0000-0004-AC17-121.11116/0000-0002-AF9A-C

Disulfide cross-linking influences symbiotic activities of nodule peptide NCR247

Autor: Elizabeth M. Nolan, Graham C. Walker, Jon Penterman, Andrew J. Wommack, Mohammed Shabab, Hartmut T. Bocker, Joel S. Griffitts, Markus F. F. Arnold, Paul A. Price

Interactions of rhizobia with legumes establish the chronic intracellular infection that underlies symbiosis. Within nodules of inverted repeat-lacking clade (IRLC) legumes, rhizobia differentiate into nitrogen-fixing bacteroids. This terminal differ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c54d394750aa038ddff8934e0760fc1
https://europepmc.org/articles/PMC5018749/

Das Bannayan-Riley-Ruvalcaba-Syndrom

Autor: M. Hocke, A. Stallmach, U. Rosenstock, K. Lohse, H.J. Düwel, F. Hörning, T. Bocker, S. Sharma

Publikováno v: Verdauungskrankheiten. 27:173-177

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e5c33c56b635d7f8769cd50998e5e820
https://doi.org/10.5414/vdp27173

Endosonographischer Nachweis eines extrapankreatischen und extraintestinalen Gastrinoms

Autor: H. Zirngibl, B. Denner, J. Schölmerich, V. D. Mohr, Gerhard Rogler, T. Bocker, G. Lehner, Volker Gross, Axel Holstege, Stephan Hollerbach

Publikováno v: DMW - Deutsche Medizinische Wochenschrift. 121:1531-1536

Anamnese und klinischer Befund: Bei einem 57jahrigen Patienten mit chronischer Diarrhoe war seit Jahren keine Diagnose gefunden worden. Die bis zu 15 wasrigen Stuhle pro Tag waren unabhangig von der Nahrungsaufnahme und ohne Blutbeimengung. Begleiten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9584f3513114183e151fe99d8c723dc1
https://doi.org/10.1055/s-2008-1043179